Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Asami Yamamura"'
Autor:
Sean J. Lund, Kathryn A. Patras, Jacqueline M. Kimmey, Asami Yamamura, Lindsay D. Butcher, Pamela G.B. Del Rosario, Gilberto E. Hernandez, Alyssa M. McCoy, Omar Lakhdari, Victor Nizet, Lawrence S. Prince
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101207- (2020)
Summary: Streptococcus agalactiae (Group B Streptococcus, GBS) is the most common neonatal pathogen. However, the cellular and molecular mechanisms for neonatal susceptibility to GBS pneumonia and sepsis are incompletely understood. Here we optimized
Externí odkaz:
https://doaj.org/article/08a3b66fdb2f440388d8fc7d11f6b5fb
Publikováno v:
eLife, Vol 6 (2017)
How tissue-resident macrophages (TRM) impact adaptive immune responses remains poorly understood. We report novel mechanisms by which TRMs regulate T cell activities at tissue sites. These mechanisms are mediated by the complement receptor of immunog
Externí odkaz:
https://doaj.org/article/07a64cb60253446e8f5dea8ce1c5841d
Autor:
Omar Lakhdari, Lawrence S. Prince, Hal M. Hoffman, Asami Yamamura, Gertrude O. Oppong-Nonterah
Publikováno v:
Journal of Innate Immunity. 11:99-108
Early exposure to inflammatory signals may have a lasting impact on immune function. Present throughout embryogenesis, macrophages are key cells providing innate immune protection to the developing fetus and newborn. Here, we have used an established
Autor:
Kathryn A. Patras, Sean Lund, Gilberto E. Hernandez, Lindsay D. Butcher, Asami Yamamura, Pamela G.B. Del Rosario, Lawrence S. Prince, Victor Nizet, Jacqueline M. Kimmey, Alyssa M. McCoy, Omar Lakhdari
Publikováno v:
iScience, vol 23, iss 6
iScience
iScience, Vol 23, Iss 6, Pp 101207-(2020)
iScience
iScience, Vol 23, Iss 6, Pp 101207-(2020)
Summary Streptococcus agalactiae (Group B Streptococcus, GBS) is the most common neonatal pathogen. However, the cellular and molecular mechanisms for neonatal susceptibility to GBS pneumonia and sepsis are incompletely understood. Here we optimized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1519a91efcae405a5d0f45cbf57759
https://escholarship.org/uc/item/72z2z2tv
https://escholarship.org/uc/item/72z2z2tv
Autor:
Hal M. Hoffman, Gertrude O. Oppong-Nonterah, Omar Lakhdari, Sean Lund, Gilberto E. Hernandez, Kathryn K. Anderson, Lawrence S. Prince, Asami Yamamura
Publikováno v:
Scientific reports, vol 9, iss 1
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Distinct macrophage subsets populate the developing embryo and fetus in distinct waves. However little is known about the functional differences between in utero macrophage populations or how they might contribute to fetal and neonatal immunity. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34c01afc5265ba85449692b890db57c
https://escholarship.org/uc/item/72c6362p
https://escholarship.org/uc/item/72c6362p
Autor:
Asami Yamamura, Marten A. Hoeksema, Mashito Sakai, Sean J. Lund, Lindsay D. Butcher, Omar Lakhdari, Gertrude O. Oppong-Nonterah, Eniko Sajti, Christopher K. Glass, Lawrence S. Prince
Publikováno v:
The Journal of Immunology. 204:152.4-152.4
Alveolar macrophages (AMs) perform specialized functions in the lung including protection against inhaled microbes and repair following injury. Neonates are particularly susceptible to lung infection and injury, suggesting immaturity of AM function.
Autor:
Sean J Lund, Kathryn A Patras, Jacqueline M Kimmey, Asami Yamamura, Lindsay D Butcher, Pamela G B Del Rosario, Gilberto E Hernandez, Alyssa M McCoy, Omar Lakhdari, Victor Nizet, Lawrence S Prince
Publikováno v:
The Journal of Immunology. 204:231.31-231.31
Group B Streptococcus (GBS) is a major neonatal pathogen but rarely causes disease in adults. We previously showed in mice that GBS escapes killing in the neonatal lung via its heavily sialylated capsule. Immune cells detect sialic acid moieties via
Autor:
Asami Yamamura, Sean J Lund, Omar Lakhdari, Mashito Sakai, Christopher K Glass, Lawrence S Prince
Publikováno v:
The Journal of Immunology. 202:187.19-187.19
Neonates are uniquely susceptible to lung infection and injury. Alveolar (AM) and interstitial (IM) lung macrophages are the major cell populations protecting the lung against inhaled microbes and facilitating wound repair. AM and IM express unique c
Autor:
Sean J Lund, Kathryn A Patras, Asami Yamamura, Gilberto Hernandez, Omar Lakhdari, Victor Nizet, Lawrence S Prince
Publikováno v:
The Journal of Immunology. 202:190.43-190.43
Group B Streptococcus (GBS) is the most common pathogen in neonates but rarely causes disease in adults. GBS causes pneumonia in newborns, suggesting a defect in lung innate immunity at birth. Using a novel neonatal mouse model of GBS pneumonia, we s
Autor:
Sean J. Lund, Kathryn A. Patras, Jacqueline M. Kimmey, Asami Yamamura, Gilberto Hernandez, Omar Lakhdari, Alyssa M. McCoy, Victor Nizet, Lawrence S. Prince
Publikováno v:
The Journal of Immunology. 200:117.30-117.30
Group B Streptococcus (Streptococcus agalactiae, GBS) causes severe infections in neonates. While not a common adult pathogen, GBS is the leading cause of congenital pneumonia. To determine the molecular mechanisms of neonatal susceptibility, we deve