Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Asako Tosaki"'
Autor:
Yumiko Uchida, Yukihiro Takahashi, Chikara Kurata, Yukihiro Morimoto, Eishin Ohtani, Asako Tosaki, Akiko Kumagai, Peter Greimel, Toshiya Nishikubo, Atsushi Miyawaki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Phototherapy converts lipophilic unconjugated bilirubin to hydrophilic bilirubin photoisomers, such as lumirubin. We comparatively used a blue light-emitting diode (LED) and a green fluorescent lamp (FL) as light sources for phototherapy of
Externí odkaz:
https://doaj.org/article/bdffe23263f54b3292751ec0464aa1f5
Autor:
Yumiko Uchida, Yukihiro Takahashi, Yukihiro Morimoto, Peter Greimel, Asako Tosaki, Akiko Kumagai, Toshiya Nishikubo, Atsushi Miyawaki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Lumirubin is the most prevalently excreted hydrophilic bilirubin photoisomer in phototherapy for neonatal jaundice caused by excess hydrophobic unconjugated bilirubin (ZZ-bilirubin). We developed a simple method to estimate the amount of lum
Externí odkaz:
https://doaj.org/article/7138e2d6069a45848503ae995c4fefbb
Autor:
Tomoyuki Yamanaka, Haruko Miyazaki, Asako Tosaki, Sankar N. Maity, Tomomi Shimogori, Nobutaka Hattori, Nobuyuki Nukina
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract A heterotrimeric transcription factor NF-Y is crucial for cell-cycle progression in various types of cells. In contrast, studies using NF-YA knockout mice have unveiled its essential role in endoplasmic reticulum (ER) homeostasis in neuronal
Externí odkaz:
https://doaj.org/article/ccbc7ee531b049c7937f687cdc397d5f
Autor:
Tomoyuki Yamanaka, Hon Kit Wong, Asako Tosaki, Peter O Bauer, Koji Wada, Masaru Kurosawa, Tomomi Shimogori, Nobutaka Hattori, Nobuyuki Nukina
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93891 (2014)
In polyglutamine (polyQ) diseases including Huntington's disease (HD), mutant proteins containing expanded polyQ stretch form aggregates in neurons. Genetic or RNAi screenings in yeast, C. elegans or Drosophila have identified multiple genes modifyin
Externí odkaz:
https://doaj.org/article/208b97340db849a39bf28664846b4fb4
Autor:
Tomoyuki Yamanaka, Asako Tosaki, Masaru Kurosawa, Kazunori Akimoto, Tomonori Hirose, Shigeo Ohno, Nobutaka Hattori, Nobuyuki Nukina
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84036 (2013)
Cell polarity plays a critical role in neuronal differentiation during development of the central nervous system (CNS). Recent studies have established the significance of atypical protein kinase C (aPKC) and its interacting partners, which include P
Externí odkaz:
https://doaj.org/article/0b1eb06fb55f45fabcd8d32a2974d11e
Autor:
Satoshi Shimozono, Mayu Sugiyama, Hiroshi Kurokawa, Hiroshi Hama, Masae Sato, Satoru Morikawa, Kumiko Kuwana, Kei Haga, Reiko Takai-Todaka, Shunsuke Inaura, Yuta Matsumura, Hidekazu Masaki, Naoto Nemoto, Ryoko Ando, Takako Kogure, Asako Tosaki, Hidehiro Fukuyama, Hideyuki Saya, Taneaki Nakagawa, Takuya Morimoto, Hiroshi Nishihara, Kazuhiko Katayama, Atsushi Miyawaki
SummaryWhile numerous diagnostic tests for COVID-19 have been developed for clinical and public health use, most of them provide binary or one-dimensional information on SARS-CoV-2 infection in pursuit of speed and ease of use. As their readouts are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f04a259218b8f3b6155a1c329739a11
https://doi.org/10.1101/2022.05.27.22274752
https://doi.org/10.1101/2022.05.27.22274752
Autor:
Takaho Terada, Fumitaka Oyama, Haruko Miyazaki, Shun-ichi Sekine, Shisako Shoji, Nobuyuki Nukina, Mikako Shirouzu, Hideaki Shimizu, Yoshiko Ishizuka-Katsura, Shigeyuki Yokoyama, Asako Tosaki, Noboru Ohsawa
Publikováno v:
The Journal of Biological Chemistry
Voltage-gated sodium channels (VGSCs) are transmembrane proteins required for the generation of action potentials in excitable cells and essential for propagating electrical impulses along nerve cells. VGSCs are complexes of a pore-forming α subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42125e3af4ed36b9158f4800f7304fef
https://doi.org/10.1074/jbc.m117.786509
https://doi.org/10.1074/jbc.m117.786509
Autor:
Asako Tosaki, Sankar N. Maity, Ryosuke Takahashi, Tomomi Shimogori, Yasuo Uchiyama, Tomoyuki Yamanaka, Nobuyuki Nukina, Masaru Kurosawa, Nobutaka Hattori, Hidemi Misawa, Masato Koike, Haruko Miyazaki
Publikováno v:
Scientific Reports
The mammalian central nervous system (CNS) contains various types of neurons with different neuronal functions. In contrast to established roles of cell type-specific transcription factors on neuronal specification and maintenance, whether ubiquitous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfe35745dace85c31665b75c8c0b6a1
Autor:
Yoshiaki Furukawa, Nobuyuki Nukina, Masaru Kurosawa, Haruko Miyazaki, Mizuki Yamada, Asako Tosaki, Tomoyuki Yamanaka
Publikováno v:
Human Molecular Genetics
In polyglutamine diseases including Huntington's disease (HD), mutant proteins containing expanded polyglutamine stretches form nuclear aggregates in neurons. Although analysis of their disease models suggested a significance of transcriptional dysre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa37cc55fcc58acbf53de2d33706429b
https://doi.org/10.1093/hmg/ddq087
https://doi.org/10.1093/hmg/ddq087
Autor:
Anand Goswami, Mizuki Yamada, Masaru Kurosawa, Chika Washizu, Nobuyuki Nukina, Peter O. Bauer, Yoko Machida, Thomas Knöpfel, Hon Kit Wong, Asako Tosaki, Takemichi Nakamura
Publikováno v:
Human Molecular Genetics. 17:3223-3235
Huntington's disease (HD) is a fatal neurodegenerative disorder. Despite a tremendous effort to develop therapeutic tools in several HD models, there is no effective cure at present. Acidosis has been observed previously in cellular and in in vivo mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2151332b45b0bf52127bb3d9f7844f4d
https://doi.org/10.1093/hmg/ddn218
https://doi.org/10.1093/hmg/ddn218