Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Asako Kumagai"'
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 5, Pp 697-709 (2021)
Abstract Aims/Introduction Tubulointerstitial fibrosis is a hallmark of diabetic nephropathy and is associated with an epithelial‐to‐mesenchymal transition (EMT) program and aberrant glycolysis. Dimeric pyruvate kinase (PK) M2 (PKM2) acts as a ke
Externí odkaz:
https://doaj.org/article/939aaa1251814c218872d610d5bde843
Autor:
Shaolan Li, Yang Fan, Asako Kumagai, Emi Kawakita, Munehiro Kitada, Keizo Kanasaki, Daisuke Koya
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 805 (2020)
Dipeptidyl peptidase (DPP)-4, a molecular target of DPP-4 inhibitors, which are type 2 diabetes drugs, is expressed in a variety of cell types, tissues and organs. DPP-4 has been shown to be involved in cancer biology, and we have recently shown that
Externí odkaz:
https://doaj.org/article/f2ef03dd2d924632820d5840d4059f46
Autor:
Kyoichiro Yazaki, Masahiro Watarai, Mitsuru Kahata, Asako Kumagai, Koji Inoue, Hiroshi Koganei, Kenji Enta, Masato Otsuka, Yasuhiro Ishii
Publikováno v:
Indian Pacing and Electrophysiology Journal, Vol 18, Iss 4, Pp 150-151 (2018)
A 67-year old male with a dual-chamber pacemaker visited for a regular check-up. An unfamiliar message emerged on the display just after placing the programmer wand. We could recognize that the pacemaker had already been in the safe back-up mode of D
Externí odkaz:
https://doaj.org/article/abd1b3fcd29043d6aa99920f6ce69f0c
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3076 (2018)
Although the global maternal mortality ratio has been consistently reduced over time, in 2015, there were still 303,000 maternal deaths throughout the world, of which 99% occurred in developing countries. Understanding pathophysiology of pregnancy co
Externí odkaz:
https://doaj.org/article/2edb318e7749497aadb9fd00b7f4b66e
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15938 (2010)
The role of p53 in the prevention of development of embryos damaged by genotoxic factors is well recognized. However, whether p53 plays an analogous role in preventing birth defects from genetic mutations remains an unanswered question. Genetic scree
Externí odkaz:
https://doaj.org/article/63a5d706308f44769fa0d88ce72848c6
Autor:
Keizo Kanasaki, Asako Kumagai
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 47:1965-1972
Due to the spread of the western style diet, which is characterized by high intake of processed food, micronutrients (vitamins and minerals) deficiency is increasing in the Japanese population of all ages and genders. During pregnancy, the elevated d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809e34e8c72ee19ae3ec92cf2304269f
https://doi.org/10.1111/jog.14770
https://doi.org/10.1111/jog.14770
Autor:
Natsuko Satomi, Shogo Kitagawa, Mitsuru Kahata, Hiroshi Koganei, Koji Inoue, Asako Kumagai, Yasuhiro Ishii, Yumi Munetsugu, Masato Otsuka
Publikováno v:
Journal of Coronary Artery Disease. 27:44-52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::177b1c9d5746807312f83311c53ebfc0
https://doi.org/10.7793/jcad.27.004
https://doi.org/10.7793/jcad.27.004
Autor:
Daisuke Koya, Asako Kumagai, Keizo Kanasaki, Shinichi Uchida, Astuo Itakura, Satoru Takeda, Eisei Sohara, Hiroshi Iijima
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 78(1)
COMT (Catechol-O-methyl transferase), an enzyme that metabolizes catechol, requires magnesium (Mg 2+ ) to maintain its activity. Low COMT activity causes insufficient 2-methoxyestradiol (2-ME), a biologically active metabolite from hydroxyestradiol,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2140de213df59a42138e5cc683873b3e
https://pubmed.ncbi.nlm.nih.gov/33840199
https://pubmed.ncbi.nlm.nih.gov/33840199
Publikováno v:
Journal of Diabetes Investigation
Journal of Diabetes Investigation, Vol 12, Iss 5, Pp 697-709 (2021)
Journal of Diabetes Investigation, Vol 12, Iss 5, Pp 697-709 (2021)
Aims/Introduction Tubulointerstitial fibrosis is a hallmark of diabetic nephropathy and is associated with an epithelial‐to‐mesenchymal transition (EMT) program and aberrant glycolysis. Dimeric pyruvate kinase (PK) M2 (PKM2) acts as a key protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d36f0a7a4b545d0485e6bea46adba4
https://pubmed.ncbi.nlm.nih.gov/33314682
https://pubmed.ncbi.nlm.nih.gov/33314682
Autor:
Emi Kawakita, Munehiro Kitada, Fan Yang, Keizo Kanasaki, Takayuki Ikeda, Asako Kumagai, Daisuke Koya, Yasuo Yoshitomi, Yuka Nakamura, Yuta Takagaki, Yasuhito Ishigaki
Publikováno v:
Molecular cancer research : MCR. 19(1)
The biological influence of antidiabetic drugs on cancer cells and diabetic cancer patients has not yet been completely elucidated. We reported that a dipeptidyl peptidase (DPP)-4 inhibitor accelerates mammary cancer metastasis by inducing epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3baa26a15346632baba58d02096be1a6
https://pubmed.ncbi.nlm.nih.gov/32994182
https://pubmed.ncbi.nlm.nih.gov/32994182