Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Asako Itakura"'
Autor:
Asako Itakura, Joseph E Aslan, Branden T Kusanto, Kevin G Phillips, Juliana E Porter, Paul K Newton, Xiaolin Nan, Robert H Insall, Jonathan Chernoff, Owen J T McCarty
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73063 (2013)
Neutrophils serve as a first line of defense in innate immunity owing in part to their ability to rapidly migrate towards chemotactic factors derived from invading pathogens. As a migratory function, neutrophil chemotaxis is regulated by the Rho fami
Externí odkaz:
https://doaj.org/article/f5469803a69e4e63a91570a553c19c5f
Publikováno v:
The Journal of Dermatology. 50:596-607
Publikováno v:
The Journal of Dermatology
Little attention has been given to the burden of chronic urticaria (CU) in Japan compared with other skin diseases, such as atopic dermatitis (AD) and psoriasis. The primary objective of the RELEASE study was to evaluate the real‐life quality‐of
Autor:
Sandra M. Baker-Groberg, Asako Itakura, Christoph Gerdes, Jeevan Maddala, Owen J. T. McCarty, Andras Gruber, Ralf Vetter, Erik I. Tucker, Jevgenia Zilberman-Rudenko
Publikováno v:
Cellular and Molecular Bioengineering. 9:496-508
Thrombus growth at the site of vascular injury is mediated by the sequential events of platelet recruitment, activation and aggregation concomitant with the initiation of the coagulation cascade, resulting in local thrombin generation and fibrin form
Autor:
Asako Itakura, Owen J. T. McCarty
Publikováno v:
American Journal of Physiology-Cell Physiology. 305:C348-C354
Autophagy is an essential cellular mechanism for cell homeostasis and survival by which damaged cellular proteins are sequestered in autophagosomal vesicles and cleared through lysosomal machinery. The autophagy pathway also plays an important role i
Autor:
Jiaqing Pang, Jonathan Chernoff, Asako Itakura, Joseph E. Aslan, Cassandra P. Loren, Garth W. Tormoen, Sandra M. Baker, Kristina M. Haley, Owen J. T. McCarty
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1544-1551
Objective— Rho GTPase proteins play a central role in regulating the dynamics of the platelet actin cytoskeleton. Yet, little is known regarding how Rho GTPase activation coordinates platelet activation and function. In this study, we aimed to char
Autor:
Claire E. Burkum, Owen J. T. McCarty, Kathleen G. Lanzer, Miles P. Davenport, David L. Woodland, Frank M. Szaba, Mykola Pinkevych, Lawrence W. Kummer, Michael L. Freeman, Stephen T. Smiley, Alan D. Roberts, Marcia A. Blackman, Asako Itakura
Publikováno v:
Journal of Autoimmunity. 42:71-79
Human herpesviruses establish lifelong latency. Viral recrudescence can lead to the development of cancers, immunoproliferative disorders, transplantation complications, and thrombocytopenia. Although platelet-specific autoantibodies have been report
Autor:
Owen J. T. McCarty, Asako Itakura, Akira Asari, Scott Foster, Larry S. Sherman, S. G. Matsumoto, Clayton W. Winkler
Publikováno v:
Matrix Biology. 32:160-168
Inflammatory demyelinating diseases like multiple sclerosis are characterized by mononuclear cell infiltration into the central nervous system. The glycosaminoglycan hyaluronan and its receptor, CD44, are implicated in the initiation and progression
Autor:
David K. Robinson, Cristina Puy, Tiffany T. Chu, Laura D. Healy, Owen J. T. McCarty, Alan Bylund, Elizabeth E. Gardiner, Kevin G. Phillips, Asako Itakura
Background Neutrophils, the most populous innate immune cell type, are the first responders to sites of infection and inflammation. Neutrophils can release their DNA to form extracellular traps (NETs), webs of DNA and granular proteases that contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ad5180ddeec833283e8b64805f2d9c
https://europepmc.org/articles/PMC4935600/
https://europepmc.org/articles/PMC4935600/
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Objective: Coagulation factor XI (FXI) has been shown to contribute to thrombus formation on collagen or tissue factor (TF)-coated surfaces in vitro and in vivo by enhancing thrombin generation. Whether the role of the intrinsic pathway of coagulatio