Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Asahi Haijima"'
Publikováno v:
Journal of Physiological Sciences, Vol 74, Iss 1, Pp 1-11 (2024)
Abstract Perfluorooctane sulfonate (PFOS) exerts adverse effects on neuronal development in young population. Limited evidences have shown that early-life PFOS exposure holds a potential risk for developing age-related neurodegenerative diseases such
Externí odkaz:
https://doaj.org/article/95cbef2c9c3842eba53e069cb7046cfd
Autor:
Shin‐ichiro Horigane, Yukihiro Ozawa, Jun Zhang, Hiroe Todoroki, Pan Miao, Asahi Haijima, Yuchio Yanagawa, Shuhei Ueda, Shigeo Nakamura, Masaki Kakeyama, Sayaka Takemoto‐Kimura
Publikováno v:
FEBS Open Bio, Vol 10, Iss 8, Pp 1436-1446 (2020)
Multiple genetic factors related to autism spectrum disorder (ASD) have been identified, but the biological mechanisms remain obscure. Timothy syndrome (TS), associated with syndromic ASD, is caused by a gain‐of‐function mutation, G406R, in the p
Externí odkaz:
https://doaj.org/article/8a4818c11bb34e5a8d4cfa3e5c7b552a
Autor:
Miski Aghnia Khairinisa, Yusuke Takatsuru, Izuki Amano, Michifumi Kokubo, Asahi Haijima, Wataru Miyazaki, Noriyuki Koibuchi
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Thyroid hormones (THs) play crucial roles in general and brain development. Even if the hypothyroidism is mild, it may alter brain function, resulting in irreversible behavioral alterations. Although various behavioral analyses have been conducted, t
Externí odkaz:
https://doaj.org/article/114bf9416d594471a153f952c986a291
Autor:
Toshihiro Endo, Masaki Kakeyama, Yukari Uemura, Asahi Haijima, Hiroyuki Okuno, Haruhiko Bito, Chiharu Tohyama
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50741 (2012)
An increasing prevalence of mental health problems has been partly ascribed to abnormal brain development that is induced upon exposure to environmental chemicals. However, it has been extremely difficult to detect and assess such causality particula
Externí odkaz:
https://doaj.org/article/85b8d82d2bf64199a641604ba76be0a3
Publikováno v:
Physiology. 38
It has been reported that the exposure to environmental chemicals including endocrine-disrupting chemicals in early life can cause developmental diseases in children. We previously reported that the lactational exposure to perfluorooctane sulfonate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e873b8e2be2e172db2ca3b4c7e001c5
https://doi.org/10.1152/physiol.2023.38.s1.5731989
https://doi.org/10.1152/physiol.2023.38.s1.5731989
Autor:
Shuhei Ueda, Pan Miao, Yukihiro Ozawa, Hiroe Todoroki, Shigeo Nakamura, Shin-ichiro Horigane, Masaki Kakeyama, Jun Zhang, Asahi Haijima, Sayaka Takemoto-Kimura, Yuchio Yanagawa
Publikováno v:
FEBS Open Bio, Vol 10, Iss 8, Pp 1436-1446 (2020)
FEBS Open Bio
FEBS Open Bio
Multiple genetic factors related to autism spectrum disorder (ASD) have been identified, but the biological mechanisms remain obscure. Timothy syndrome (TS), associated with syndromic ASD, is caused by a gain‐of‐function mutation, G406R, in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752202a377d2c3c54d188ccd9d7484ff
https://doi.org/10.1002/2211-5463.12924
https://doi.org/10.1002/2211-5463.12924
The neurotoxic effect of lactational PFOS exposure on cerebellar functional development in male mice
Autor:
Ayane Ninomiya, Abdallah Mshaty, Asahi Haijima, Hiroyuki Yajima, Michifumi Kokubo, Miski Aghnia Khairinisa, Winda Ariyani, Yuki Fujiwara, Sumiyasu Ishii, Nobutake Hosoi, Hirokazu Hirai, Izuki Amano, Noriyuki Koibuchi
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 159
Recent studies showed a possible association between perfluorooctane sulfonate (PFOS) and developmental disabilities. We previously found the specific effects of PFOS exposure on learning and memory, however, its effect on the other developmental dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bf3e018f3d9ff42865b5283fb14a2b
https://pubmed.ncbi.nlm.nih.gov/34871666
https://pubmed.ncbi.nlm.nih.gov/34871666
SAT-454 A Novel Role of Thyroid Hormone Receptor in Synaptic Plasticity in Cerebellar Purkinje Cells
Autor:
Michifumi Kokubo, Hirokazu Hirai, Noriyuki Koibuchi, Ayane Ninomiya, Wataru Miyazaki, Asahi Haijima, Nobutake Hosoi, Izuki Amano
Publikováno v:
Journal of the Endocrine Society
Thyroid hormone (TH) is essential for the development and the maintenance of the brain function. TH action is mediated by TH receptor (TR). TR binds to a specific DNA sequence on TH-target genes and thus functions as a ligand-dependent transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7dd48711adbabfdeeaa6e6e01352b93
https://doi.org/10.1210/jendso/bvaa046.1706
https://doi.org/10.1210/jendso/bvaa046.1706
Publikováno v:
Journal of the Endocrine Society
Iodine is one of the essential micronutrient which is required for the synthesis of thyroid hormones. Thus, iodine deficiency may result in the hypothyroidism. Iodine deficiency is one of the most common causes of preventable mental retardation and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62a05b92aef74d4ebe08a2bfc1fca24
https://doi.org/10.1210/jendso/bvaa046.1180
https://doi.org/10.1210/jendso/bvaa046.1180
Autor:
Yusuke Takatsuru, Michifumi Kokubo, Noriyuki Koibuchi, Asahi Haijima, Izuki Amano, Wataru Miyazaki, Miski Aghnia Khairinisa
Publikováno v:
Pharmacology and Clinical Pharmacy Research. 4
Thyroid hormone (TH) play crucial roles in the growth and development of brain. Efficiency of TH during the perinatal period results in severe mental and physical retardation, known as cretinism in humans. Animal models have largely focused on mild a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5967fc5c689e4ad925beac0b87471dff
https://doi.org/10.15416/pcpr.v4i3.25264
https://doi.org/10.15416/pcpr.v4i3.25264