Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Asaf Sela"'
Autor:
Yael Goldfarb, Noam Kadouri, Ben Levi, Asaf Sela, Yonatan Herzig, Ronald N. Cohen, Anthony N. Hollenberg, Jakub Abramson
Publikováno v:
Cell Reports, Vol 15, Iss 3, Pp 651-665 (2016)
The thymus provides a unique microenvironment enabling development and selection of T lymphocytes. Medullary thymic epithelial cells (mTECs) play a pivotal role in this process by facilitating negative selection of self-reactive thymocytes and the ge
Externí odkaz:
https://doaj.org/article/5f3e4fc792f841e8ae1bef5a54ac861a
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003882 (2013)
Short insertions and deletions (InDels) comprise an important part of the natural mutational repertoire. InDels are, however, highly deleterious, primarily because two-thirds result in frame-shifts. Bypass through slippage over homonucleotide repeats
Externí odkaz:
https://doaj.org/article/f8e0e148b8f147efbac2308c53e456d3
Autor:
Asaf Sela, Jakub Abramson, Ben Levi, Noam Kadouri, Yonatan Herzig, Ronald N. Cohen, Yael Goldfarb, Anthony N. Hollenberg
Publikováno v:
Cell Reports, Vol 15, Iss 3, Pp 651-665 (2016)
SummaryThe thymus provides a unique microenvironment enabling development and selection of T lymphocytes. Medullary thymic epithelial cells (mTECs) play a pivotal role in this process by facilitating negative selection of self-reactive thymocytes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae984776c4e1b085372f193432ca588c
Autor:
Haim Y. Cohen, Clotilde Guyon, Michael W. McBurney, Anna Chuprin, Yonatan Herzig, Shir Katz, Irit Sagi, Adi Jacob, Moran Rathaus, Jakub Abramson, Ayelet Avin, Ben Levi, Asaf Sela, Matthieu Giraud, Moran Grossman, Eystein S. Husebye, Yael Goldfarb
Publikováno v:
Nature immunology. 16(7)
Aire is a transcriptional regulator that induces the promiscuous expression of thousands of tissue-restricted antigens (TRAs) in medullary thymic epithelial cells (mTECs), a step critical for the induction of immunological self-tolerance. Studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b379ee37166f2c5d26250d3fece89cf
https://pubmed.ncbi.nlm.nih.gov/26086133
https://pubmed.ncbi.nlm.nih.gov/26086133
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003882 (2013)
PLoS Genetics
PLoS Genetics
Short insertions and deletions (InDels) comprise an important part of the natural mutational repertoire. InDels are, however, highly deleterious, primarily because two-thirds result in frame-shifts. Bypass through slippage over homonucleotide repeats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8ad63cf24e99dfb8826ba7bc38719a
https://doi.org/10.1371/journal.pgen.1003882
https://doi.org/10.1371/journal.pgen.1003882