Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Asaf Poran"'
Autor:
Alexander Muik, Bonny Gaby Lui, Jasmin Quandt, Huitian Diao, Yunguan Fu, Maren Bacher, Jessica Gordon, Aras Toker, Jessica Grosser, Orkun Ozhelvaci, Katharina Grikscheit, Sebastian Hoehl, Niko Kohmer, Yaniv Lustig, Gili Regev-Yochay, Sandra Ciesek, Karim Beguir, Asaf Poran, Isabel Vogler, Özlem Türeci, Ugur Sahin
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112888- (2023)
Summary: Evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has led to the emergence of sublineages with different patterns of neutralizing antibody evasion. We report that Omicron BA.4/BA.5 breakthrough inf
Externí odkaz:
https://doaj.org/article/9beefa8d290946d3b470f10ccdbe5236
Autor:
Asaf Poran, Dewi Harjanto, Matthew Malloy, Christina M. Arieta, Daniel A. Rothenberg, Divya Lenkala, Marit M. van Buuren, Terri A. Addona, Michael S. Rooney, Lakshmi Srinivasan, Richard B. Gaynor
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract Background The ongoing COVID-19 pandemic has created an urgency to identify novel vaccine targets for protective immunity against SARS-CoV-2. Early reports identify protective roles for both humoral and cell-mediated immunity for SARS-CoV-2.
Externí odkaz:
https://doaj.org/article/9f61d50420b745d5900a6a515483100a
Autor:
Saiama Waqar, Mark Awad, Ramaswamy Govindan, David Spigel, Richard Gaynor, Edward Garon, Aaron Lisberg, Melissa Moles, Jennifer Tepper, April Lamb, Amy Wanamaker, Zakaria Khondker, John Srouji, Jesse Dong, Asaf Poran, Kristen Balogh, Meghan Bushway, Mark DeMario, Lakshmi Srinivasan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/87f0b6347d22484b87bc7e8bf04d1d1e
Autor:
Asaf Madi, Asaf Poran, Eric Shifrut, Shlomit Reich-Zeliger, Erez Greenstein, Irena Zaretsky, Tomer Arnon, Francois Van Laethem, Alfred Singer, Jinghua Lu, Peter D Sun, Irun R Cohen, Nir Friedman
Publikováno v:
eLife, Vol 6 (2017)
Diversity of T cell receptor (TCR) repertoires, generated by somatic DNA rearrangements, is central to immune system function. However, the level of sequence similarity of TCR repertoires within and between species has not been characterized. Using n
Externí odkaz:
https://doaj.org/article/3937974f5c114e8194e5e132044691d1
Autor:
Alexander Muik, Bonny Gaby Lui, Huitian Diao, Yunguan Fu, Maren Bacher, Aras Toker, Jessica Grosser, Orkun Ozhelvaci, Katharina Grikscheit, Sebastian Hoehl, Niko Kohmer, Yaniv Lustig, Gili Regev-Yochay, Sandra Ciesek, Karim Beguir, Asaf Poran, Özlem Türeci, Ugur Sahin
The continued evolution of the SARS-CoV-2 Omicron variant has led to the emergence of numerous sublineages with different patterns of evasion from neutralizing antibodies. We investigated neutralizing activity in immune sera from individuals vaccinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d13ac22b4550728ab61dea679e8b173
https://doi.org/10.1101/2022.12.15.520569
https://doi.org/10.1101/2022.12.15.520569
Autor:
John L. Perez, Isabel Vogler, Evelyna Derhovanessian, Gábor Boros, David A. Cooper, Camila R. Fontes-Garfias, Kristen E. Pascal, Armin Schultz, Alexander Muik, Martin Bexon, Pei Yong Shi, Peter Koch, Ann Kathrin Eller, Verena Lörks, Mark Cutler, Daniel Maurus, Ludwig Heesen, Philip R. Dormitzer, Ugur Sahin, Kathrin U. Jansen, Manuel Tonigold, Jan Grützner, Azita J. Mahiny, Corinna Rosenbaum, Stefanie Bolte, Mathias Vormehr, Marie Cristine Kühnle, Sybille Baumann, Asaf Poran, Alexander Ulges, Alexandra Kemmer-Brück, Christos A. Kyratsous, Dirk Becker, Özlem Türeci, Alina Baum, Sebastian Brachtendorf, Lena M. Kranz, Carsten Boesler, Rolf Hilker, Tania Palanche, Julian Sikorski, Nicole Bidmon, Ulrich Luxemburger, David J. Langer, Jesse Z. Dong, Gábor Szabó, Jasmin Quandt, Katalin Karikó, Jonas Reinholz
Publikováno v:
Nature. 595:572-577
BNT162b2, a lipid nanoparticle (LNP) formulated nucleoside-modified messenger RNA (mRNA) that encodes the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S) stabilized in the prefusion conformation, has demonstrated 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0154147b441b18af735efb00657c62f
https://doi.org/10.1038/s41586-021-03653-6
https://doi.org/10.1038/s41586-021-03653-6
Autor:
Christina M. Arieta, Yushu Joy Xie, Daniel A. Rothenberg, Huitian Diao, Dewi Harjanto, Shirisha Meda, Krisann Marquart, Byron Koenitzer, Tracey E. Sciuto, Alexander Lobo, Adam Zuiani, Stefanie A. Krumm, Carla Iris Cadima Couto, Stephanie Hein, André P. Heinen, Thomas Ziegenhals, Yunpeng Liu-Lupo, Annette B. Vogel, John R. Srouji, Stephanie Fesser, Kaushik Thanki, Kerstin Walzer, Theresa A. Addona, Özlem Türeci, Uğur Şahin, Richard B. Gaynor, Asaf Poran
Publikováno v:
Cell. 186:2392-2409.e21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9953902c43ac69914921cbcd7e3eb591
https://doi.org/10.1016/j.cell.2023.04.007
https://doi.org/10.1016/j.cell.2023.04.007
Autor:
Karim Beguir, Marcin J. Skwark, Yunguan Fu, Thomas Pierrot, Nicolas Lopez Carranza, Alexandre Laterre, Ibtissem Kadri, Abir Korched, Anna U. Lowegard, Bonny Gaby Lui, Bianca Sänger, Yunpeng Liu, Asaf Poran, Alexander Muik, Uğur Şahin
Publikováno v:
Computers in Biology and Medicine. 155:106618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62fc2f0404519f6b1b8b8c1a0a264ae4
https://doi.org/10.1016/j.compbiomed.2023.106618
https://doi.org/10.1016/j.compbiomed.2023.106618
Autor:
Mark M. Awad, Ramaswamy Govindan, Kristen N. Balogh, David R. Spigel, Edward B. Garon, Meghan E. Bushway, Asaf Poran, Joong Hyuk Sheen, Victoria Kohler, Ekaterina Esaulova, John Srouji, Suchitra Ramesh, Rohit Vyasamneni, Binisha Karki, Tracey E. Sciuto, Himanshu Sethi, Jesse Z. Dong, Melissa A. Moles, Kelledy Manson, Michael S. Rooney, Zakaria S. Khondker, Mark DeMario, Richard B. Gaynor, Lakshmi Srinivasan
Publikováno v:
Cancer cell. 40(9)
Neoantigens arising from mutations in tumor DNA provide targets for immune-based therapy. Here, we report the clinical and immune data from a Phase Ib clinical trial of a personalized neoantigen-vaccine NEO-PV-01 in combination with pemetrexed, carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935d29553f74594992b9744ac0684da4
https://pubmed.ncbi.nlm.nih.gov/36027917
https://pubmed.ncbi.nlm.nih.gov/36027917
Autor:
Alexander Muik, Bonny Gaby Lui, Ann-Kathrin Wallisch, Maren Bacher, Julia Mühl, Jonas Reinholz, Orkun Ozhelvaci, Nina Beckmann, Ramón de la Caridad Güimil Garcia, Asaf Poran, Svetlana Shpyro, Andrew Finlayson, Hui Cai, Qi Yang, Kena A. Swanson, Özlem Türeci, Uğur Şahin
Publikováno v:
Science (New York, N.Y.). 375(6581)
The globally circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern Omicron (B.1.1.529) has a large number of mutations, especially in the spike protein, indicating that recognition by neutralizing antibodies may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ac0f26ba4022eb4b25952ab87d688d
https://pubmed.ncbi.nlm.nih.gov/35040667
https://pubmed.ncbi.nlm.nih.gov/35040667