Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Arzoo Orfany"'
Autor:
Aybuke Celik, Arzoo Orfany, Jason Dearling, Pedro J. del Nido, James D. McCully, Filiz Bakar-Ates
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114524- (2023)
Prostate and ovarian cancers affect the male and female reproductive organs and are among the most common cancers in developing countries. Previous studies have demonstrated that cancer cells have a high rate of aerobic glycolysis that is present in
Externí odkaz:
https://doaj.org/article/cce0aa03ba1944a8a3a23f1a1a7ab412
Autor:
Borami Shin, MD, Mossab Y. Saeed, MD, Jesse J. Esch, MD, Alvise Guariento, MD, David Blitzer, MD, Kamila Moskowitzova, MD, Giovanna Ramirez-Barbieri, MD, Arzoo Orfany, MD, Jerusha K. Thedsanamoorthy, BA, Douglas B. Cowan, PhD, James A. Inkster, PhD, Erin R. Snay, BRS, Steven J. Staffa, MS, Alan B. Packard, PhD, David Zurakowski, PhD, Pedro J. del Nido, MD, James D. McCully, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 871-888 (2019)
Summary: Mitochondrial dysfunction is the determinant insult of ischemia-reperfusion injury. Autologous mitochondrial transplantation involves supplying one’s healthy mitochondria to the ischemic region harboring damaged mitochondria. The authors u
Externí odkaz:
https://doaj.org/article/babe002306fd4682ab8fe8ad9fed1494
Autor:
David Zurakowski, James D. McCully, Thomas V. Rousselle, Viktoria Weixler, Isaac E. Stillman, Takashi Kido, David Blitzer, James A. H. Inkster, Alvise Guariento, Amandeep Bajwa, Mossab Y Saeed, Arzoo Orfany, Thomas Duignan, Erin Snay, Ilias P. Doulamis, Samir M. Parikh, Alan B. Packard, Pedro J. del Nido, Borami Shin
Publikováno v:
Am J Physiol Renal Physiol
Acute kidney injury is a common clinical disorder and one of the major causes of morbidity and mortality in the postoperative period. In this study, the safety and efficacy of autologous mitochondrial transplantation by intra-arterial injection for r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edc7168ee1f5ed5c6e0af9cf262c693
https://doi.org/10.1152/ajprenal.00255.2020
https://doi.org/10.1152/ajprenal.00255.2020
Autor:
Steven J. Staffa, James D. McCully, David Zurakowski, Pedro J. del Nido, Ilias P. Doulamis, Giovanna Ramirez-Barbieri, Arzoo Orfany, David Blitzer, Borami Shin, Kamila Moskowitzova, Alvise Guariento
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 160:e15-e29
Objective To investigate preischemic intracoronary autologous mitochondrial transplantation (MT) as a therapeutic strategy for prophylactic myocardial protection in a porcine model of regional ischemia-reperfusion injury (IRI). Methods The left coron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d092e6e8f8b8037ae4f730f2d2f69cc0
https://doi.org/10.1016/j.jtcvs.2019.06.111
https://doi.org/10.1016/j.jtcvs.2019.06.111
Autor:
James A. H. Inkster, Arzoo Orfany, Mossab Y Saeed, Viktoria Weixler, Takashi Kido, Amandeep Bajwa, Alvise Guariento, Erin Snay, Samir M. Parikh, Pedro J. del Nido, Isaac E. Stillman, Thomas Duignan, Borami Shin, Alan B. Packard, Thomas V. Rousselle, David Zurakowski, Ilias P. Doulamis, James D. McCully, David Blitzer
Publikováno v:
Circulation. 142
Introduction: Acute kidney injury (AKI) is a common clinical disorder and one of the major causes of morbidity and mortality during the postoperative period. In this study, we investigated the safety and efficacy of autologous mitochondrial transplan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4355e41e884bf98be056c0602cfd5bf2
https://doi.org/10.1161/circ.142.suppl_3.14991
https://doi.org/10.1161/circ.142.suppl_3.14991
Autor:
David Zurakowski, Ilias P. Doulamis, Alvise Guariento, Takashi Kido, Thomas Duignan, Pedro J. del Nido, James D. McCully, Arzoo Orfany
OBJECTIVES Type 2 diabetes causes mitochondrial dysfunction, which increases myocardial susceptibility to ischaemia–reperfusion injury. We investigated the efficacy of transplantation of mitochondria isolated from diabetic or non-diabetic donors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1efef4795cc8b951887fcf66320fda
https://hdl.handle.net/11577/3464986
https://hdl.handle.net/11577/3464986
Autor:
David Blitzer, Ilias P. Doulamis, Giovanna Ramirez Barbieri, Kamila Moskowitzova, Alvise Guariento, Arzoo Orfany, Borami Shin, James D. McCully, Pedro J. del Nido
Background We have previously demonstrated the efficacy of mitochondrial transplantation (MT) for the treatment of ischemia-reperfusion injury (IRI). We now investigate the efficacy of delayed MT by intracoronary administration in a model of regional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7554d8b41be94a58a70c7d5e315fedd5
https://hdl.handle.net/11577/3465111
https://hdl.handle.net/11577/3465111
Autor:
David Blitzer, Jerusha K. Thedsanamoorthy, James A. H. Inkster, Rouan Yao, Kaifeng Liu, Kamila Moskowitzova, Alan B. Packard, Alvise Guariento, Douglas B. Cowan, Borami Shin, Giovanna Ramirez-Barbieri, Ilias P. Doulamis, Arzoo Orfany, James D. McCully, Pedro J. del Nido, Khadija Iken, Gary A. Visner, Erin Snay
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 318(1)
The most common cause of acute lung injury is ischemia-reperfusion injury (IRI), during which mitochondrial damage occurs. We have previously demonstrated that mitochondrial transplantation is an efficacious therapy to replace or augment mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ad8dbdca5e2addba09e8ef24015cca
https://pubmed.ncbi.nlm.nih.gov/31774303
https://pubmed.ncbi.nlm.nih.gov/31774303
Autor:
David Zurakowski, Borami Shin, Pedro J. del Nido, Khadija Iken, Ingeborg Friehs, Giovanna Ramirez-Barbieri, David Blitzer, Arzoo Orfany, James D. McCully, Kamila Moskowitzova, Alvise Guariento
Publikováno v:
Mitochondrion. 46
Previously, we have demonstrated that the transplantation of autologous mitochondria is cardioprotective. No immune or autoimmune response was detectable following the single injection of autologous mitochondria. To expand the therapeutic potential a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f100c2be617ffaf2745168250210a5f8
https://pubmed.ncbi.nlm.nih.gov/30476365
https://pubmed.ncbi.nlm.nih.gov/30476365
Autor:
Jerusha K. Thedsanamoorthy, David Blitzer, Kaifeng Liu, Arzoo Orfany, Rouan Yao, Gary A. Visner, P J del Nido, Giovanna Ramirez-Barbieri, James D. McCully, Borami Shin, Douglas B. Cowan, Kamila Moskowitzova, Alvise Guariento
Publikováno v:
The Journal of Heart and Lung Transplantation. 37:S22-S23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13fdaaeff34c487c8af325872571993f
https://doi.org/10.1016/j.healun.2018.01.033
https://doi.org/10.1016/j.healun.2018.01.033