Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aryan M. A. Namboodiri"'
Autor:
Abhilash P. Appu, John R. Moffett, Peethambaran Arun, Sean Moran, Vikram Nambiar, Jishnu K. S. Krishnan, Narayanan Puthillathu, Aryan M. A. Namboodiri
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Canavan disease is caused by mutations in the gene encoding aspartoacylase (ASPA), a deacetylase that catabolizes N-acetylaspartate (NAA). The precise involvement of elevated NAA in the pathogenesis of Canavan disease is an ongoing debate. In the pre
Externí odkaz:
https://doaj.org/article/e1631f1ff95845ab838fe1462d225129
Publikováno v:
Journal of cellular biochemistry. 117(3)
Metabolic networks are significantly altered in neoplastic cells. This altered metabolic program leads to increased glycolysis and lipogenesis and decreased dependence on oxidative phosphorylation and oxygen consumption. Despite their limited mitocho
Autor:
Prasanth S, Ariyannur, Peethambaran, Arun, Erin S, Barry, Brian, Andrews-Shigaki, Asamoah, Bosomtwi, Haiying, Tang, Reed, Selwyn, Neil E, Grunberg, John R, Moffett, Aryan M A, Namboodiri
Publikováno v:
Journal of neuroscience research. 91(7)
N-acetylaspartate (NAA) is recognized as a noninvasive diagnostic neuronal marker for a host of neuropsychiatric disorders using magnetic resonance spectroscopy (MRS). Numerous correlative clinical studies have found significant decreases in NAA leve
Publikováno v:
Advances in experimental medicine and biology. 576
Autor:
Aryan M A, Namboodiri, John R, Moffett, Peethambaran, Arun, Raji, Mathew, Sreela, Namboodiri, Asha, Potti, Jeremy, Hershfield, Batool, Kirmani, David M, Jacobowitz, Chikkathur N, Madhavarao
Publikováno v:
Advances in experimental medicine and biology. 576
Autor:
John R, Moffett, Aryan M A, Namboodiri
Publikováno v:
Advances in experimental medicine and biology. 576
Autor:
John R, Moffett, Aryan M A, Namboodiri
Publikováno v:
Advances in experimental medicine and biology. 576
Autor:
D. Carleton Gajdusek, Clarence J. Gibbs, John R. Moffett, Chettemgere N S Venkateshan, Maneth Gravell, Rekha Narayanan, Aryan M A Namboodiri, Karen Blinder
Publikováno v:
Journal of neurovirology. 2(6)
Quinolinate (QUIN), a metabolite in the kynurenine pathway of tryptophan degradation and a neurotoxin that is thought to act through the NMD A receptor system, was localized in cultured peripheral blood monocytes/macrophages from SIV-infected monkeys
Autor:
John Moffett, Suzannah B. Tieman, Daniel R. Weinberger, Joseph T. Coyle, Aryan M. A. Namboodiri
N-acetylaspartate, or NAA, is the acetylated form of the amino acid aspartate, and it is present exclusively in the nervous system. Indeed, NAA is one of the most highly concentrated chemicals found in the brain of humans and animals, and yet the fun
Autor:
Patrick M Long, Scott W Tighe, Heather E Driscoll, John R Moffett, Aryan M A Namboodiri, Mariano S Viapiano, Sean E Lawler, Diane M Jaworski
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80714 (2013)
Cancer is associated with globally hypoacetylated chromatin and considerable attention has recently been focused on epigenetic therapies. N-acetyl-L-aspartate (NAA), the primary storage form of acetate in the brain, and aspartoacylase (ASPA), the enz
Externí odkaz:
https://doaj.org/article/dcec63c806e14239a56208440cd2e011