Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Arwin J. Brouwer"'
Autor:
Carl C. L. Schuurmans, Arwin J. Brouwer, Jacobus A. W. Jong, Geert-Jan P. H. Boons, Wim E. Hennink, Tina Vermonden
Publikováno v:
ACS Omega, Vol 6, Iss 40, Pp 26302-26310 (2021)
Externí odkaz:
https://doaj.org/article/59cd254a8c9d49329ac6ea7f0ed3197d
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:5055-5063
Peptido sulfonyl fluoride derivatives were designed and synthesized containing a substituent on the alpha position (αPSFs) with respect to the sulfonyl fluoride electrophilic trap. The chemical reactivity of these α-substituted amino sulfonyl fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d9f7e30b23e0d4e4cf4c434b33b933
https://doi.org/10.1016/j.bmc.2017.07.019
https://doi.org/10.1016/j.bmc.2017.07.019
Autor:
Roland J. Pieters, Arwin J. Brouwer, Rob Ruijtenbeek, Jie Shi, Suhela Sharif, Marko Anderluh, Tihomir Tomašič
Publikováno v:
FEBS Letters, str. 1872-1883 : Ilustr., Vol. 591, iss. 13, 2017
COBISS-ID: 23399429
COBISS-ID: 23399429
O-GlcNAcylation of proteins regulates important cellular processes. A few reports noted that O-GlcNAcylation exhibits cross-talk with tyrosine phosphorylation. With an activity-based microarray analysis of 256 tyrosine kinase peptide substrates, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890f1b172bab7ead8651d759520edd03
https://doi.org/10.1002/1873-3468.12708
https://doi.org/10.1002/1873-3468.12708
Autor:
Rob M. J. Liskamp, Achim Krüger, Christian Dubiella, Stephan A. Sieber, Arwin J. Brouwer, Michael Groll, Malte Gersch, Haissi Cui
Publikováno v:
Angewandte Chemie. 126:12163-12167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b07b53b42f8c57119d2269920cbebfea
https://doi.org/10.1002/ange.201406964
https://doi.org/10.1002/ange.201406964
Publikováno v:
Tetrahedron. 70:4002-4007
An efficient multigram scale synthesis of a new asymmetric triazacyclophane scaffold, the ATAC (Asymmetric-TAC) scaffold, bearing three selectively removable groups is described. This scaffold is slightly more rigid than our frequently used TAC (TriA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f43c308a8eb258512d3eda589a06e11
https://doi.org/10.1016/j.tet.2014.04.084
https://doi.org/10.1016/j.tet.2014.04.084
Autor:
Serena Tschan, Anika M. Jonker, Rob M. J. Liskamp, Makoah N. Aminake, Fanny Joanny, Paul R. Werkhoven, Benjamin Mordmüller, Lena Wagner, Gabriele Pradel, Arwin J. Brouwer, Sarah Knittel
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:3576-3584
Despite declining numbers of cases and deaths, malaria remains a major public health problem in many parts of the world. Today, case management relies heavily on a single class of antimalarial compounds: artemisinins. Hence, development of resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6b790efacb29c74e1265dae2c62723
https://doi.org/10.1128/aac.00742-12
https://doi.org/10.1128/aac.00742-12
Autor:
Arwin J. Brouwer, Helmus van de Langemheen, Rob M. J. Liskamp, Johan Kemmink, John A. W. Kruijtzer
Publikováno v:
The Journal of Organic Chemistry. 77:10058-10064
The synthesis of cyclic peptides containing a thioester handle using a sulfo-click linker is reported. These cyclic peptides can be coupled to N-terminal cysteine-containing constructs via native chemical ligation. A successful application of a cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8583cb2ffb09afb4fa79fa8d8f46b3
https://doi.org/10.1021/jo3015566
https://doi.org/10.1021/jo3015566
Autor:
Tania Meijneke, Rob M. J. Liskamp, Remco de Jong, Ronald C. Elgersma, Dirk T. S. Rijkers, George Posthuma, Arwin J. Brouwer
Publikováno v:
Organic & Biomolecular Chemistry, 4(19), 3587-3597. ROYAL SOC CHEMISTRY
The incorporation of a single beta-aminoethane sulfonyl amide moiety in a highly amyloidogenic peptide sequence resulted in a complete loss of amyloid fibril formation. Instead, supramolecular folding morphologies were observed. Subsequent chemoselec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f963393d3047b1e08d3cc3199430dd
https://doi.org/10.1039/b606875h
https://doi.org/10.1039/b606875h
Autor:
John A. F. Joosten, Roland J. Pieters, Rob M. J. Liskamp, Arwin J. Brouwer, Fatna Ait el Maate, Niels T. H. Tholen, Dirk T. S. Rijkers, G. Wilma van Esse
Publikováno v:
European Journal of Organic Chemistry. 2005:3182-3185
A facile and high-yielding synthesis of multivalent 1,4-disubstituted 1,2,3-triazole-linked glycodendrimers is described. Azido carbohydrates are linked by a CuI-catalyzed [3+2] cycloaddition reaction to dendritic acetylenes using microwave irradiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be76bcfc54dad762339d4a4f9999fd6a
https://doi.org/10.1002/ejoc.200500216
https://doi.org/10.1002/ejoc.200500216
Autor:
Rob M. J. Liskamp, Arwin J. Brouwer
Publikováno v:
European Journal of Organic Chemistry. 2005:487-495
The convergent synthesis of novel dendrimeric systems containing NLO-ligands is described. The poor solubility properties of dendrimers of type A containing NLO-ligands enticed us into developing novel dendrimers of type B leading to the convergent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef8418c79f68608550173ddab6d31a4f
https://doi.org/10.1002/ejoc.200400609
https://doi.org/10.1002/ejoc.200400609