Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Arwen E. Frick-Cheng"'
Autor:
Arwen E. Frick-Cheng, Anna Sintsova, Sara N. Smith, Ali Pirani, Evan S. Snitkin, Harry L. T. Mobley
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT More than half of women will experience a urinary tract infection (UTI), with uropathogenic Escherichia coli (UPEC) causing ~80% of uncomplicated cases. Iron acquisition systems are essential for uropathogenesis, and UPEC strains encode high
Externí odkaz:
https://doaj.org/article/44c625d9a85448c6b49a3823b1ef5635
Autor:
Arwen E. Frick-Cheng, Anna Sintsova, Sara N. Smith, Michael Krauthammer, Kathryn A. Eaton, Harry L. T. Mobley
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Uropathogenic Escherichia coli (UPEC) is the primary causative agent of uncomplicated urinary tract infections (UTIs). UPEC fitness and virulence determinants have been evaluated in a variety of laboratory settings, including a well-establis
Externí odkaz:
https://doaj.org/article/c8f1e4ce7fd44182891fad739b3ee032
Autor:
Bo Hu, Pratick Khara, Liqiang Song, Aung Soe Lin, Arwen E. Frick-Cheng, M. Lorena Harvey, Timothy L. Cover, Peter J. Christie
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Helicobacter pylori colonizes about half of humans worldwide, and its presence in the gastric mucosa is associated with an increased risk of gastric adenocarcinoma, gastric lymphoma, and peptic ulcer disease. H. pylori strains carrying the c
Externí odkaz:
https://doaj.org/article/ded14b6461864e43b67be2bc02197a75
Autor:
Arwen E. Frick-Cheng, Tasia M. Pyburn, Bradley J. Voss, W. Hayes McDonald, Melanie D. Ohi, Timothy L. Cover
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
ABSTRACT Bacterial type IV secretion systems (T4SSs) can function to export or import DNA, and can deliver effector proteins into a wide range of target cells. Relatively little is known about the structural organization of T4SSs that secrete effecto
Externí odkaz:
https://doaj.org/article/ff3f9e2b638b4b1aa62e543179963f0a
Autor:
Anna Sintsova, Arwen E Frick-Cheng, Sara Smith, Ali Pirani, Sargurunathan Subashchandrabose, Evan S Snitkin, Harry Mobley
Publikováno v:
eLife, Vol 8 (2019)
Uropathogenic Escherichia coli (UPEC) is the major causative agent of uncomplicated urinary tract infections (UTIs). A common virulence genotype of UPEC strains responsible for UTIs is yet to be defined, due to the large variation of virulence factor
Externí odkaz:
https://doaj.org/article/43dc7bcd0bed4eff969fec9a9b401e29
Autor:
Jeong Min Chung, Michael J Sheedlo, Anne M Campbell, Neha Sawhney, Arwen E Frick-Cheng, Dana Borden Lacy, Timothy L Cover, Melanie D Ohi
Publikováno v:
eLife, Vol 8 (2019)
Bacterial type IV secretion systems (T4SSs) are molecular machines that can mediate interbacterial DNA transfer through conjugation and delivery of effector molecules into host cells. The Helicobacter pylori Cag T4SS translocates CagA, a bacterial on
Externí odkaz:
https://doaj.org/article/a09e84dbd1fd47248cd182384fd9c270
Autor:
Anna Sintsova, Harry L. T. Mobley, Arwen E Frick-Cheng, Evan S. Snitkin, Ali Pirani, Sara N. Smith
Publikováno v:
mBio, 13 (3)
More than half of women will experience a urinary tract infection (UTI), with uropathogenic Escherichia coli (UPEC) causing ~80% of uncomplicated cases. Iron acquisition systems are essential for uropathogenesis, and UPEC strains encode highly divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538a115173c2b180d5cd6498a7ae9680
https://doi.org/10.1101/2021.11.12.468464
https://doi.org/10.1101/2021.11.12.468464
Autor:
Anna Sintsova, Arwen E Frick-Cheng, Harry L. T. Mobley, Michael Krauthammer, Kathryn A. Eaton, Sara N. Smith
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
mBio
mBio
Different experimental models have been used to study UPEC pathogenesis, including in vitro cultures in different media, tissue culture, and mouse models of infection. The last is especially important since it allows evaluation of mechanisms of patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab258782f8f26091295c11b9e161170
https://doi.org/10.1101/2020.02.18.954842
https://doi.org/10.1101/2020.02.18.954842
Autor:
Timothy L. Cover, Arwen E. Frick-Cheng, Mark S. McClain, Richard M. Peek, Giovanni Suarez, John T. Loh, Aung Soe Lin, M. Lorena Harvey, W. Hayes McDonald, Samuel D R Dooyema
Publikováno v:
Infect Immun
Helicobacter pylori colonizes the stomach in about half of the world's population. H. pylori strains containing the cag pathogenicity island (cag PAI) are associated with a higher risk of gastric adenocarcinoma or peptic ulcer disease than cag PAI-ne