Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Arwen Conod"'
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110490- (2022)
Summary: How metastatic cells arise is unclear. Here, we search for the induction of recently characterized pro-metastatic states as a surrogate for the origin of metastasis. Since cell-death-inducing therapies can paradoxically promote metastasis, w
Externí odkaz:
https://doaj.org/article/90c3409d083544adbe4f0dd4d75ddd5e
Autor:
Arnaud Duquet, Alice Melotti, Sonakshi Mishra, Monica Malerba, Chandan Seth, Arwen Conod, Ariel Ruiz i Altaba
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 7, Pp 882-901 (2014)
Abstract The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in vitro assays do not fully predict metastatic behavior, and the majority of studies have used c
Externí odkaz:
https://doaj.org/article/9335cc5f8719458cbd007765a16efc97
Autor:
Chandan Seth, Christophe Mas, Arwen Conod, Jens Mueller, Karsten Siems, Monika Kuciak, Isabel Borges, Ariel Ruiz I Altaba
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168170 (2016)
The WNT-TCF signaling pathway participates in adult tissue homeostasis and repair, and is hyperactive in a number of human diseases including cancers of the colon. Whereas to date there are no antagonists approved for patient use, a potential problem
Externí odkaz:
https://doaj.org/article/6c75967e282544b9b63179d43644bc9c
Autor:
Ariel Ruiz i Altaba, Grigori Singovski, Irene Siegl-Cachedenier, Arwen Conod, Carolina Bernal, Monika Kuciak
Publikováno v:
Journal of Molecular Cell Biology, Vol. 8, No 2 (2016) pp. 157-173
Journal of Molecular Cell Biology
Journal of Molecular Cell Biology
How metastases develop is not well understood and no genetic mutations have been reported as specific metastatic drivers. Here we have addressed the idea that epigenetic reprogramming by GLI-regulated pluripotent stemness factors promotes metastases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f209083ffb40a9cef9fb6c13ec88d4
http://doc.rero.ch/record/331528/files/JMCB_8_2_157.pdf
http://doc.rero.ch/record/331528/files/JMCB_8_2_157.pdf
Autor:
Ariel Ruiz i Altaba, Sonakshi Mishra, Alice Melotti, Monica Malerba, Chandan Seth, Arnaud Duquet, Arwen Conod
Publikováno v:
EMBO Molecular Medicine. 6:882-901
The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in vitro assays do not fully predict metastatic behavior, and the majority of studies have used cloned cel
Autor:
Ariel Ruiz i Altaba, Christophe Mas, Jens Mueller, Monika Kuciak, Isabel Borges, Chandan Seth, Arwen Conod, Karsten Siems
Publikováno v:
PLoS ONE
PLOS ONE, Vol. 11, No 12 (2016) P. e0168170
PLoS ONE, Vol 11, Iss 12, p e0168170 (2016)
PLOS ONE, Vol. 11, No 12 (2016) P. e0168170
PLoS ONE, Vol 11, Iss 12, p e0168170 (2016)
The WNT-TCF signaling pathway participates in adult tissue homeostasis and repair, and is hyperactive in a number of human diseases including cancers of the colon. Whereas to date there are no antagonists approved for patient use, a potential problem