Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Arvinder Kapur"'
Autor:
Sejal Sharma, Liping Feng, Nicha Boonpattrawong, Arvinder Kapur, Lisa Barroilhet, Manish S. Patankar, Spencer S. Ericksen
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Focused screening on target-prioritized compound sets can be an efficient alternative to high throughput screening (HTS). For most biomolecular targets, compound prioritization models depend on prior screening data or a target structure. For
Externí odkaz:
https://doaj.org/article/917f8e3cc1944718acb1f5328cb44ee3
Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells
Autor:
Yousef Alharbi, Arvinder Kapur, Mildred Felder, Lisa Barroilhet, Timothy Stein, Bikash R. Pattnaik, Manish S. Patankar
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The Na+/K+-ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate the effect of drug-induced oxidative stress on NKA activity. The natural product, plumbagin increases
Externí odkaz:
https://doaj.org/article/711cb0ad0da842b3aed61841711db73e
Autor:
Yang Liu, Rebecca J Whelan, Bikash R Pattnaik, Kai Ludwig, Enkateswar Subudhi, Helen Rowland, Nick Claussen, Noah Zucker, Shitanshu Uppal, David M Kushner, Mildred Felder, Manish S Patankar, Arvinder Kapur
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53178 (2012)
Novel strategies are necessary to improve chemotherapy response in advanced and recurrent endometrial cancer. Here, we demonstrate that terpenoids present in the Steam Distilled Extract of Ginger (SDGE) are potent inhibitors of proliferation of endom
Externí odkaz:
https://doaj.org/article/af28e86b6aa54ab8b87e3ae4a9a1f045
Autor:
Arvinder Kapur, Jose M Ayuso, Shujah Rehman, Santosh Kumari, Mildred Felder, Zach Stenerson, Melisa C Skala, Dave Beebe, Lisa Barroilhet, Manish S Patankar
Publikováno v:
Reproduction. 165:617-628
In brief Developing novel therapies to cure and manage endometriosis is a major unmet need that will benefit over 180 million women worldwide. Results from the current study suggest that inhibitors of oxidative phosphorylation may serve as novel agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84009d5f58ee52db01f145063299dd01
https://doi.org/10.1530/rep-22-0265
https://doi.org/10.1530/rep-22-0265
Publikováno v:
J Proteome Res
Glycans, which are widely distributed on most proteins and cell surfaces, are a class of important biomolecules playing important roles in various biological processes such as immune response and cellular communication. Modern mass spectrometry (MS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24f924867404324b280ec349999d437
https://doi.org/10.1021/acs.jproteome.2c00773
https://doi.org/10.1021/acs.jproteome.2c00773
Autor:
Germán González, Conor L. Evans, W. Peter Hansen, Jawad Hoballah, Sinyoung Jeong, Fatima Mubarak, Petra B. Krauledat, Lauren A. Austin, Daniel W. Cramer, Arvinder Kapur, Manish S. Patankar, Nicholas H. Nowell, Alexander Ho
Publikováno v:
ACS Sens
Although levels of the circulating ovarian cancer marker (CA125) can distinguish ovarian masses that are likely to be malignant and correlate with severity of disease, serum CA125 has not proved useful in general population screening. Recently, cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f6e3bf21c168ac035cfdb892785782
https://doi.org/10.1021/acssensors.0c00567
https://doi.org/10.1021/acssensors.0c00567
Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells
Autor:
Manish S. Patankar, Bikash R. Pattnaik, Timothy J. Stein, Arvinder Kapur, Yousef Alharbi, Mildred Felder, Lisa Barroilhet
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
The Na+/K+-ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate the effect of drug-induced oxidative stress on NKA activity. The natural product, plumbagin increases oxygen ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80565a1db9f4bed3c8cc5416dc2b190
https://doaj.org/article/711cb0ad0da842b3aed61841711db73e
https://doaj.org/article/711cb0ad0da842b3aed61841711db73e
Autor:
Arvinder Kapur, Pooja Mehta, Aaron D Simmons, Spencer S. Ericksen, Geeta Mehta, Sean P. Palecek, Mildred Felder, Zach Stenerson, Amruta Nayak, Jose Maria Ayuso Dominguez, Manish Patankar, Lisa M. Barroilhet
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2297
Oxidative phosphorylation is an active metabolic pathway in cancer. Atovaquone is an oral medication that inhibits oxidative phosphorylation and is FDA-approved for the treatment of malaria. We investigated its potential anti-cancer properties by mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e2564ca0940eec3e5900df08a74b08
https://doi.org/10.3390/cancers14092297
https://doi.org/10.3390/cancers14092297
Autor:
Antonio Romo Chavez, Lisa Barroilhet, Aleksandar K. Stanic, Jessica Vazquez, Manish S. Patankar, Gladys E. Lopez, Mildred A. Felder, Melina Chavarria, Nathan Karst, Arvinder Kapur
Publikováno v:
Am J Reprod Immunol
PROBLEM: We hypothesize that activated peritoneal immune cells can be redirected to target ovarian tumors. Here, we obtain fundamental knowledge of the peritoneal immune environment through deep immunophenotyping of T cells, dendritic cells (DC) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3cd780dba942663a8fb88d463251f9
https://doi.org/10.1111/aji.13284
https://doi.org/10.1111/aji.13284
Autor:
Germán González, Manish S. Patankar, W. Peter Hansen, Conor L. Evans, Arvinder Kapur, Lauren A. Austin, Petra B. Krauledat, Nicholas H. Nowell, Daniel W. Cramer, Jawad Hoballah, Fatima Mubarak, Sinyoung Jeong
Publikováno v:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII.
We recently developed a digital cytometric assay using plasmonic nanoparticles to quantify the bound ovarian cancer marker (CA125) on single cells. We demonstrate the quantification capability of our novel digital cytometry method by discriminating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5f6aaa595cdb2e219550b04bbfe417f
https://doi.org/10.1117/12.2545088
https://doi.org/10.1117/12.2545088