Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Arvind P Pathak"'
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164288 (2016)
Plasminogen activator inhibitor-1 (PAI-1) is elevated in various cancers, where it has been shown to effect cell migration and invasion and angiogenesis. While, PAI-1 is a secreted protein, its intercellular levels are increased in cancer cells. Cons
Externí odkaz:
https://doaj.org/article/c230776f174e4cf09b811171c2f14fd7
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63146 (2013)
To gain new insights into the relationship between angiogenic factors in breast cancer and their effect on extracellular matrix (ECM) remodeling and metastasis, we characterized and validated the "metastatic signature" of human breast cancer cell lin
Externí odkaz:
https://doaj.org/article/bb127bbb510f4c698edddc76d0bded02
Autor:
Samata M Kakkad, Marie-France Penet, Alireza Akhbardeh, Arvind P Pathak, Meiyappan Solaiyappan, Venu Raman, Dieter Leibfritz, Kristine Glunde, Zaver M Bhujwalla
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81869 (2013)
Hypoxic tumor microenvironments result in an aggressive phenotype and resistance to therapy that lead to tumor progression, recurrence, and metastasis. While poor vascularization and the resultant inadequate drug delivery are known to contribute to d
Externí odkaz:
https://doaj.org/article/ce3e5fa08c9647ab87fab7d3e1ceaac7
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22643 (2011)
Knowledge of the three-dimensional (3D) architecture of blood vessels in the brain is crucial because the progression of various neuropathologies ranging from Alzheimer's disease to brain tumors involves anomalous blood vessels. The challenges in obt
Externí odkaz:
https://doaj.org/article/27202f482d7b4a448c7cff92fc9f4255
Autor:
Janaka Senarathna, Hang Yu, Callie Deng, Alice L. Zou, John B. Issa, Darian H. Hadjiabadi, Stacy Gil, Qihong Wang, Betty M. Tyler, Nitish V. Thakor, Arvind P. Pathak
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Measuring multiple neurophysiologic variables usually requires bulky benchtop optical systems and working with anesthetized animals. Here the authors present a miniature portable microscope for neurovascular imaging in awake rodents, combining fluore
Externí odkaz:
https://doaj.org/article/3faa9c8a2870428caac1dc902f7821bd
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C1524-C1538
Vascularization is a crucial step during musculoskeletal tissue regeneration via bioengineered constructs or grafts. Functional vasculature provides oxygen and nutrients to the graft microenvironment, facilitates wound healing, enhances graft integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7223b5fe5546d11674f6aab03af4ca
https://doi.org/10.1152/ajpcell.00195.2022
https://doi.org/10.1152/ajpcell.00195.2022
Autor:
Yucheng Shen, Qihong Wang, Hiren R. Modi, Arvind P. Pathak, Romergryko G. Geocadin, Nitish V. Thakor, Janaka Senarathna
Publikováno v:
Annals of Biomedical Engineering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37fcc56b1161e9b24dc4438a4a5b3c35
https://doi.org/10.1007/s10439-023-03210-4
https://doi.org/10.1007/s10439-023-03210-4
Autor:
Yuhang Fu, Yucheng Shen, Ze Ou, Johnnie A. Johnson, Arvind P. Pathak, Romergryko G. Geocadin, Nitish V. Thakor, Janaka Senarathna
Publikováno v:
2023 11th International IEEE/EMBS Conference on Neural Engineering (NER).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60bc35b5e2f6f4caf4b57e6fc528976b
https://doi.org/10.1109/ner52421.2023.10123864
https://doi.org/10.1109/ner52421.2023.10123864
Autor:
Akanksha Bhargava, Benjamin Monteagudo, Priyanka Kushwaha, Janaka Senarathna, Yunke Ren, Ryan C. Riddle, Manisha Aggarwal, Arvind P. Pathak
Publikováno v:
Nature Methods. 19:242-254
Despite advances in imaging, image-based vascular systems biology has remained challenging because blood vessel data are often available only from a single modality or at a given spatial scale, and cross-modality data are difficult to integrate. Ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736a1d272ed708f29cf94d5fc531df70
https://doi.org/10.1038/s41592-021-01363-5
https://doi.org/10.1038/s41592-021-01363-5
Autor:
Venu Raman, Carlotta Glackin, Horst Burger, Paul Van Diest, Zaver Bhujwalla, Dmitri Artemov, Scott Kominsky, Arvind P. Pathak, Flonne Wildes, Yoshinori Kato, Farhad Vesuna, Paul T. Winnard, Yelena Mironchik
Aggressive cancer phenotypes are a manifestation of many different genetic alterations that promote rapid proliferation and metastasis. In this study, we show that stable overexpression of Twist in a breast cancer cell line, MCF-7, altered its morpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226764eb56bf3ab6eb3158891a2d6503
https://doi.org/10.1158/0008-5472.c.6494051
https://doi.org/10.1158/0008-5472.c.6494051
