Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Arvind Manoharan"'
Publikováno v:
Clinical & Experimental Allergy. 46:696-704
Background We examined the paradoxical hypothesis that the alpha receptor inverse agonist doxazosin might produce beneficial effects in allergic rhinitis. Objectives To evaluate single and chronic dosing effects of doxazosin on nasal airflow and symp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47cb697760c7d28d31f17b14b1f5e4e
https://doi.org/10.1111/cea.12700
https://doi.org/10.1111/cea.12700
Publikováno v:
Lung
Introduction Long-acting muscarinic antagonists confer improvements in spirometry when used in addition to inhaled corticosteroids and long-acting beta-agonists (ICS/LABA) in COPD. The dual objectives of this proof of concept study were to evaluate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cfecee1393b10b4bfc7e5d7e0291f3
https://doi.org/10.1007/s00408-015-9839-y
https://doi.org/10.1007/s00408-015-9839-y
Publikováno v:
Annals of Allergy, Asthma & Immunology. 115:17-20
Background Impulse oscillometry (IOS) is a novel method of assessing airway resistance. IOS is rarely used in assessing airway resistance after bronchoprovocation in adult asthma. Objective To ascertain the degree of change in IOS measurements seen i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6594fe1d2238c4485aa89d3c2aa168ce
https://doi.org/10.1016/j.anai.2015.04.022
https://doi.org/10.1016/j.anai.2015.04.022
Publikováno v:
Lung. 193:47-51
Guidelines advocate the use of spirometry to assess pulmonary function in asthmatic patients. Commonly used measures include forced expiratory volume in 1 s (FEV1), forced expiratory ratio (FEV1/FVC), and forced mid-expiratory flow between 25 and 75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbfeaff1b89c5f15a6788b98df0a551
https://doi.org/10.1007/s00408-014-9674-6
https://doi.org/10.1007/s00408-014-9674-6
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:601-603
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b19aca792de1249e0c81e74156f780c0
https://doi.org/10.1016/j.jaci.2015.12.1336
https://doi.org/10.1016/j.jaci.2015.12.1336
Autor:
Sunny Jabbal, Philip M. Short, Brian Lipworth, William Anderson, Ashley Morrison, Arvind Manoharan
Publikováno v:
Airway Pharmacology and Treatment.
BACKGROUND Beta-blockers remain underused in patients with chronic obstructive pulmonary disease (COPD) and cardiovascular disease. AIM We compared how different inhaled therapies affect tolerability of bisoprolol and carvedilol in moderate to severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9609494b8fd429654309352ac272cce
https://doi.org/10.1183/1393003.congress-2017.pa3247
https://doi.org/10.1183/1393003.congress-2017.pa3247
Publikováno v:
Airway Pharmacology and Treatment.
Background Tiotropium is a long acting antimuscarinic (LAMA), licenced as triple therapy with inhaled corticosteroid and long acting beta-agonist (ICS/LABA). There may be a synergistic benefit between LAMA and LABA as a consequence of receptor cross-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c65122e1f85cc777b4840487f93e64f
https://doi.org/10.1183/1393003.congress-2017.pa1799
https://doi.org/10.1183/1393003.congress-2017.pa1799
Publikováno v:
Clinical & Experimental Allergy. 44:1240-1245
BACKGROUND Although airway hyperresponsiveness (AHR) is a defining feature of asthma pathophysiology, bronchial challenge testing is not routinely used in primary care asthma management. OBJECTIVE The aim of this study was to evaluate the potential r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5e013ed0b37eada5ed5b0a96ee5014
https://doi.org/10.1111/cea.12352
https://doi.org/10.1111/cea.12352
Publikováno v:
Clinical Science. 127:635-643
The murine asthma model shows that switching off airway β2 receptors with an inverse agonist may confer anti-inflammatory effects as well as corticosteroid-sparing activity. We have assessed for any corticosteroid-sparing effects of propranolol, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2d512b0a6e57f2b6519b36df7b64ab
https://doi.org/10.1042/cs20140249
https://doi.org/10.1042/cs20140249
Publikováno v:
The Lancet Respiratory Medicine. 2:497-506
The small airways in the distal lung have been called the quiet zone because they are difficult to assess and treat in patients with asthma who have disproportionate impairment of small airway function. Evidence is accumulating to support a distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c125a5fb9ebfd673d6b83371a3783d4
https://doi.org/10.1016/s2213-2600(14)70103-1
https://doi.org/10.1016/s2213-2600(14)70103-1