Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Arvind Konkimalla"'
Autor:
Arvind Konkimalla, Satoshi Konishi, Yoshihiko Kobayashi, Preetish Kadur Lakshminarasimha Murthy, Lauren Macadlo, Ananya Mukherjee, Zachary Elmore, So-Jin Kim, Ann Marie Pendergast, Patty J. Lee, Aravind Asokan, Lars Knudsen, Jose Javier Bravo-Cordero, Aleksandra Tata, Purushothama Rao Tata
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105114- (2022)
Summary: Epithelial cells of diverse tissues are characterized by the presence of a single apical domain. In the lung, electron microscopy studies have suggested that alveolar type-2 epithelial cells (AT2s) en face multiple alveolar sacs. However, ap
Externí odkaz:
https://doaj.org/article/73d87ff05eac443eba891db8672a1af3
Autor:
Arvind Konkimalla, Nicholas E. Banovich, Hiroaki Katsura, Yoshihiko Kobayashi, Rebecca F. Lee, Aleksandra Tata, Jianhong Ou, Purushothama Rao Tata, Jonathan A. Kropski
Publikováno v:
Nat Cell Biol
Stem cells undergo dynamic changes in response to injury to regenerate lost cells. However, the identity of transitional states and the mechanisms that drive their trajectories remain understudied. Using lung organoids, multiple in vivo repair models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9effdf6a1f01c3b71628d25d66e9b2d4
https://doi.org/10.1038/s41556-020-0542-8
https://doi.org/10.1038/s41556-020-0542-8
Autor:
Aleksandra Tata, Jianhong Ou, Hiroaki Katsura, Nicholas E. Banovich, Purushothama Rao Tata, Rebecca F. Lee, Jonathan A. Kropski, Arvind Konkimalla, Yoshihiko Kobayashi
Stem cell senescence is often seen as an age associated pathological state in which cells acquire an abnormal and irreversible state. Here, we show that alveolar stem cell differentiation during lung regeneration involves a unique previously uncharac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2255fc80304a5a6fb22acb0b9d2cff
Autor:
Caitlin E. Edwards, Arvind Konkimalla, Ralph S. Baric, Scott H. Randell, Aleksandra Tata, Brook E. Heaton, Purushothama Rao Tata, Richard C. Boucher, Takanori Asakura, Yu Mikami, Patty J. Lee, Yoshihiko Kobayashi, Vishwaraj Sontake, Hiroaki Katsura, Nicholas S. Heaton, Ethan J. Fritch
Publikováno v:
Cell Stem Cell
Coronavirus infection causes diffuse alveolar damage leading to acute respiratory distress syndrome. The absence of ex vivo models of human alveolar epithelium is hindering an understanding of coronavirus disease 2019 (COVID-19) pathogenesis. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633624ec61260918eeee5fbace94d5d6
https://doi.org/10.1016/j.stem.2020.10.005
https://doi.org/10.1016/j.stem.2020.10.005
Publikováno v:
Cell stem cell. 21(6)
Tissue homeostasis and regeneration are mediated by programs of adult stem cell renewal and differentiation. However, the mechanisms that regulate stem cell fates under such widely varying conditions are not fully understood. Using single cell techni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e196c42ac53b017cec43c8d4b3a9ab
https://pubmed.ncbi.nlm.nih.gov/29174333
https://pubmed.ncbi.nlm.nih.gov/29174333
Autor:
Purushothama Rao Tata, Daniel T. Montoro, Hongmei Mou, Ryan D. Chow, Jayaraj Rajagopal, Mari Mino-Kenudson, Lida P. Hariri, Leif W. Ellisen, Srinivas Vinod Saladi, Shioko Kimura, Arvind Konkimalla, Angela R. Shih, Anne Bara, Aleksandra Tata
Publikováno v:
Developmental Cell. 44:679-693.e5
We show that the loss or gain of transcription factor programs that govern embryonic cell-fate specification is associated with a form of tumor plasticity characterized by the acquisition of alternative cell fates normally characteristic of adjacent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efde5b51ce512c3f1143f510661cf09
https://doi.org/10.1016/j.devcel.2018.02.024
https://doi.org/10.1016/j.devcel.2018.02.024
Autor:
Robert N. Husson, Nancy A. Woychik, Jared D. Sharp, Irina O. Vvedenskaya, Arvind Konkimalla, Jonathan W. Cruz, Eric D. Hoffer, Bryce E. Nickels, Christine M. Dunham, Tatsuya Maehigashi
Publikováno v:
Nature Communications. 6
Toxin-antitoxin (TA) systems are implicated in the downregulation of bacterial cell growth associated with stress survival and latent tuberculosis infection, yet the activities and intracellular targets of these TA toxins are largely uncharacterized.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9aa4d7ea6d8f3bd5c7191d3546f3cb
https://doi.org/10.1038/ncomms8480
https://doi.org/10.1038/ncomms8480