Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Arvind K. Singla"'
Autor:
Kayla L. Marritt, Karys M. Hildebrand, Kurt N. Hildebrand, Arvind K. Singla, Franz J. Zemp, Douglas J. Mahoney, Frank R. Jirik, Michael J. Monument
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionSoft tissue sarcomas (STS) are highly metastatic, connective-tissue lineage solid cancers. Immunologically, sarcomas are frequently characterized by a paucity of tumor infiltrating lymphocytes and an immune suppressive microenvironment. A
Externí odkaz:
https://doaj.org/article/e8e244d2e9ed4365ae8f75807960f42a
Autor:
Karys M Hildebrand, Arvind K Singla, Reid McNeil, Kayla L Marritt, Kurt N Hildebrand, Franz Zemp, Jahanara Rajwani, Doha Itani, Pinaki Bose, Douglas J Mahoney, Frank R Jirik, Michael J Monument
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253864 (2021)
Sarcomas are rare, difficult to treat, mesenchymal lineage tumours that affect children and adults. Immunologically-based therapies have improved outcomes for numerous adult cancers, however, these therapeutic strategies have been minimally effective
Externí odkaz:
https://doaj.org/article/2eb9820a225e40e79ee67a99c614faac
Autor:
Michael J. Monument, Doha Itani, Douglas J. Mahoney, Asmaa Affan, Joseph K. Kendal, Arvind K. Singla, Frank R. Jirik, Mark Ungrin, Abdullah Al-Ani, Kurt N. Hildebrand
Publikováno v:
Clin Orthop Relat Res
BACKGROUND The putative benefit of rhBMP-2 is in the setting of limb reconstruction using structural allografts, whether it be allograft-prosthetic composites, osteoarticular allografts, or intercalary segmental grafts. There are also potential advan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e665823c96a8aac09f50ddd19efd787e
https://doi.org/10.1097/corr.0000000000001422
https://doi.org/10.1097/corr.0000000000001422
Autor:
Michael J. Monument, Vincent M. Rotello, Doha Itani, Uwe H. F. Bunz, Kai Seehafer, Ngoc D. B. Le, Charlene M. Downey, Jinsong Han, Daniel F. Moyano, Gyan Prakash, Arvind K. Singla, Frank R. Jirik, Yingying Geng
Publikováno v:
Chem Commun (Camb)
We report a polymer-based sensor that rapidly detects cancer based on changes in serum protein levels. Using three ratiometric fluorescence outputs, this simple system identifies early stage and metastatic lung cancer with a high level of accuracy ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669fcb2e7c9c587af94100be242c3ba1
https://doi.org/10.1039/c9cc04854e
https://doi.org/10.1039/c9cc04854e
Autor:
Arvind K Singla, Rama Krishna Gurram, Arun Chauhan, Neeraj Khatri, Rakesh M Vohra, Ravinder S Jolly, Javed N Agrewala
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107051 (2014)
BACKGROUND: Caerulomycin A (CaeA) is a known antifungal and antibiotic agent. Further, CaeA is reported to induce the expansion of regulatory T cell and prolongs the survival of skin allografts in mouse model of transplantation. In the current study,
Externí odkaz:
https://doaj.org/article/72e4bf04c6c7412889758f079c076ede
Autor:
Michael J. Monument, Doha Itani, Jahanara Rajwani, Douglas J. Mahoney, Pinaki Bose, Arvind K. Singla, Frank R. Jirik, Kurt N. Hildebrand, Franz J. Zemp, Kayla L. Marritt, Reid McNeil, Karys M. Hildebrand
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253864 (2021)
PLoS ONE
PLoS ONE
Sarcomas are rare, difficult to treat, mesenchymal lineage tumours that affect children and adults. Immunologically-based therapies have improved outcomes for numerous adult cancers, however, these therapeutic strategies have been minimally effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31058be633730f8182883bfc33aadf0
https://doaj.org/article/2eb9820a225e40e79ee67a99c614faac
https://doaj.org/article/2eb9820a225e40e79ee67a99c614faac
Autor:
Charlene M Downey, Arvind K Singla, Michelle L Villemaire, Helen R Buie, Steven K Boyd, Frank R Jirik
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41685 (2012)
Techniques for visualizing and quantifying the microvasculature of tumors are essential not only for studying angiogenic processes but also for monitoring the effects of anti-angiogenic treatments. Given the relatively limited information that can be
Externí odkaz:
https://doaj.org/article/3118dd24489d4287b41782de0547d9cd
Publikováno v:
Clinical & Experimental Metastasis. 31:705-714
Metastatic disease accounts for most deaths due to breast cancer and thus identification of novel ways to prevent this complication remains a key goal. A frequently employed preclinical model of breast cancer metastasis relies on xenografted human MD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78285c65ed69abfc07a498b154ac6840
https://doi.org/10.1007/s10585-014-9661-6
https://doi.org/10.1007/s10585-014-9661-6
Ratiometric array of conjugated polymers–fluorescent protein provides a robust mammalian cell sensor
Autor:
Vincent M. Rotello, Uwe H. F. Bunz, Krishnendu Saha, Subinoy Rana, Mahdieh Yazdani, Avinash Bajaj, S. Gokhan Elci, Markus Bender, Arvind K. Singla, Frank R. Jirik, Rubul Mout
© 2016 American Chemical Society.Supramolecular complexes of a family of positively charged conjugated polymers (CPs) and green fluorescent protein (GFP) create a fluorescence resonance energy transfer (FRET)-based ratiometric biosensor array. Selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877ffeeb4e485f2ab5c38808f9d608fa
http://hdl.handle.net/10044/1/31445
http://hdl.handle.net/10044/1/31445
Autor:
Avinash Bajaj, Bo Yan, Arvind K. Singla, Oscar R. Miranda, Frank R. Jirik, Rubul Mout, S. Gokhan Elci, Subinoy Rana, Vincent M. Rotello
Publikováno v:
ACS Nano. 6:8233-8240
Rapid and sensitive methods of discriminating between healthy tissue and metastases are critical for predicting disease course and designing therapeutic strategies. We report here the use of an array of gold nanoparticle–green fluorescent protein e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8a3e18f608f10f6d0c7584dbf32db1
https://doi.org/10.1021/nn302917e
https://doi.org/10.1021/nn302917e