Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Arvind Govindarajan"'
Publikováno v:
Neuron. 69(1):132-146
SummaryThe late-phase of long-term potentiation (L-LTP), the cellular correlate of long-term memory, induced at some synapses facilitates L-LTP expression at other synapses receiving stimulation too weak to induce L-LTP by itself. Using glutamate unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7013b7f173637dfb8856b761b492a692
Autor:
Ming Gao Zhao, Guosong Liu, Arvind Govindarajan, Inna Slutsky, Xiang Zhao, Susumu Tonegawa, Bo I. Li, Ling Zhang, Min Zhuo, Chao Huang, Long Jun Wu, Nashat Abumaria
Publikováno v:
Neuron. 65(2):165-177
SUMMARY Learning and memory are fundamental brain functions affected by dietary and environmental factors. Here, we show that increasing brain magnesium using a newly developed magnesium compound (magnesium-L-threonate, MgT) leads to the enhancement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d3bc184842d8e986006ad53b4c280b
Publikováno v:
Nature Reviews Neuroscience. 7:575-583
Long-term memory and its putative synaptic correlates the late phases of both long-term potentiation and long-term depression require enhanced protein synthesis. On the basis of recent data on translation-dependent synaptic plasticity and on the supr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ced29449d12c97039331c8e87be378
https://doi.org/10.1038/nrn1937
https://doi.org/10.1038/nrn1937
Publikováno v:
Neuron. 44:59-73
Memory and synaptic plasticity exhibit distinct temporal phases, with long-lasting forms distinguished by their dependence on macromolecular synthesis. Prevailing models for the molecular mechanisms underlying long-lasting synaptic plasticity have la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363a2bd4f05186126d7eaa8c47310093
https://doi.org/10.1016/j.neuron.2004.09.013
https://doi.org/10.1016/j.neuron.2004.09.013
Publikováno v:
Cell. 116(3):467-479
Enduring forms of synaptic plasticity and memory require new protein synthesis, but little is known about the underlying regulatory mechanisms. Here, we investigate the role of MAPK signaling in these processes. Conditional expression of a dominant-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbd65d005e167e6cd9edf5a27977889
Autor:
Gregor Hutter, Joanne Bruno, Susan Lindquist, Danica Chen, Adriano Aguzzi, Andrew D. Steele, Erin J. Easlon, Su Ju Lin, Leonard Guarente, Arvind Govindarajan
A central focus of aging research is to determine how calorie restriction (CR) extends lifespan and delays diseases of aging. SIRT1, the mammalian ortholog of Sir2 in yeast, is a longevity factor which mediates dietary restriction in diverse species.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e2ee9ea333f890f11d899ded8b7936
