Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Arvind G. Kinhikar"'
Publikováno v:
Bioconjugate Chemistry. 24:53-62
The characterization of conjugation sites in bioconjugates is critical in the early discovery phase because site-specific conjugation improves in vivo stability and drug efficacy. We previously developed an engineered monoclonal antibody (mAb) scaffo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a350751921177e3bb6fad5e9f3787d8a
https://doi.org/10.1021/bc300413c
https://doi.org/10.1021/bc300413c
Autor:
Arvind G. Kinhikar, Diana Vargas, Laura R. Hinds, Spencer Mahaffey, Hualin Li, Suman Laal, John T. Belisle
Publikováno v:
Molecular Microbiology. 60:999-1013
Mycobacterium tuberculosis (M. tb) uses the glyoxalate bypass for intracellular survival in vivo. These studies provide evidence that the M. tb malate synthase (MS) has adapted to function as an adhesin which binds to laminin and fibronectin. This bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75f3460017e852c456ed65cf6fe12f7
https://doi.org/10.1111/j.1365-2958.2006.05151.x
https://doi.org/10.1111/j.1365-2958.2006.05151.x
Publikováno v:
Acta Tropica. 91:27-41
We have earlier shown that recombinant mouse granulocyte-macrophage colony-stimulating factor (rmGM-CSF) and methionine-enkephalin co-treatment can protect mice from malaria. We now report the bioimmunotherapeutic effect of rmGM-CSF and a synthetic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55012719b96cd62d26827eff06cc101a
https://doi.org/10.1016/j.actatropica.2004.02.009
https://doi.org/10.1016/j.actatropica.2004.02.009
Publikováno v:
Neuroimmunomodulation. 10:261-269
Objective: The effect of morphine on host defense during Leishmania donovani infection in golden hamsters was studied. Methods: Hamsters were intracardially infected with L. donovani amastigotes and then monitored by spleen touch print microscopic ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1705eb4f3b27ff90b4913c2d93e053a7
https://doi.org/10.1159/000069970
https://doi.org/10.1159/000069970
Autor:
Kristen E Bower, Ryan Preston, Emily Corner, Robert E. Murphy, Arvind G. Kinhikar, Xia Cao, Zemeda W Ainekulu, Aakash B Datt, Steven Pirie-Shepherd, Lioudmila Campbell, Gang Chen, Venkata Doppalapudi, Joselyn Del Rosario, Hanhua Huang, Bryan Oates, Rodney W. Lappe, Son Lam, Trina Osothprarop, Nancy Levin, Curt Bradshaw, Gary Woodnutt, Julie A Hoye, Judith Jimenez
Publikováno v:
Journal of medicinal chemistry. 54(5)
Novel phage-derived peptides are the first reported molecules specifically targeting human placental growth factor 1 (PlGF-1). Phage data enabled peptide modifications that decreased IC(50) values in PlGF-1/VEGFR-1 competition ELISA from 100 to 1 μM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d778774e40714032c80844e89f7bc95
https://pubmed.ncbi.nlm.nih.gov/21280651
https://pubmed.ncbi.nlm.nih.gov/21280651
Autor:
Gary H. Ward, Robert E. Murphy, Arvind G. Kinhikar, Joselyn Del Rosario, Ryan Preston, Nancy Levin, Michael J. Shields
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 53(3)
Peptides and monoclonal antibodies have both emerged as important therapeutic modalities, but each has challenges which limit their use. Non-recombinant chemical conjugation of peptides onto antibodies has the potential to minimize or eliminate altog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6cf05215036c115f0d62b6d581efb2
https://pubmed.ncbi.nlm.nih.gov/20547023
https://pubmed.ncbi.nlm.nih.gov/20547023
Autor:
Peter Andersen, Dinesh Chandra, Krishna Singh, Suman Laal, Arvind G. Kinhikar, William R. Jacobs, Tsungda Hsu, Indu Verma, Karin Weldingh
Publikováno v:
Molecular microbiology. 75(1)
ESAT6 has recently been demonstrated to cause haemolysis and macrophage lysis. Our studies demonstrate that ESAT6 causes cytolysis of type 1 and type 2 pneumocytes. Both types of pneumocytes express membrane laminin, and ESAT6 exhibits dose-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d67aee0abc74149a8e998af5fa60432
https://pubmed.ncbi.nlm.nih.gov/19906174
https://pubmed.ncbi.nlm.nih.gov/19906174
Autor:
Arvind G. Kinhikar, Prati Pal Singh
Publikováno v:
Hybridoma and hybridomics. 21(6)
Swiss mice vaccinated with Plasmodium yoelii nigeriensis-soluble antigen and saponin, following a homologous 100% lethal challenge, showed 60% protection (6 out of 10 mice survived). Monoclonal antibodies (MAbs), generated by hybridizing the Sp2/0 my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077d09c2a00db22ef4964ac8f392c3bc
https://pubmed.ncbi.nlm.nih.gov/12573112
https://pubmed.ncbi.nlm.nih.gov/12573112
Publikováno v:
Neuroimmunomodulation. 10(5)
The effect of morphine on host defense during Leishmania donovani infection in golden hamsters was studied.Hamsters were intracardially infected with L. donovani amastigotes and then monitored by spleen touch print microscopic examination. Morphine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1a96334ddb9314c794bb86440debb08
https://pubmed.ncbi.nlm.nih.gov/12759563
https://pubmed.ncbi.nlm.nih.gov/12759563