Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Arvind, Dev"'
Autor:
Seema Singh, Arvind Dev, Rakesh Verma, Anamika Pradeep, Pradeep Sathyanarayana, Jennifer M Green, Aishwarya Narayanan, Don M Wojchowski
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e38530 (2012)
Certain concepts concerning EPO/EPOR action modes have been challenged by in vivo studies: Bcl-x levels are elevated in maturing erythroblasts, but not in their progenitors; truncated EPOR alleles that lack a major p85/PI3K recruitment site nonethele
Externí odkaz:
https://doaj.org/article/4ff5658091e34af7b611e5870cf14a4a
Autor:
Arvind Dev, Kim Rance, Estelle Houde, Haydn M. Prosser, Evelyn Grau, Vinit Karur, Olga Bogacheva, Madhu P. Menon, Elizabeth I. Valoret, Susan J. Pickering, George P. Livi, Oleg Bogachev, Connie L. Erickson-Miller, Don M. Wojchowski, Caretha L. Creasy
Publikováno v:
Journal of Biological Chemistry. 283:36665-36675
During anemia erythropoiesis is bolstered by several factors including KIT ligand, oncostatin-M, glucocorticoids, and erythropoietin. Less is understood concerning factors that limit this process. Experiments performed using dual-specificity tyrosine
Autor:
Paul J. Chapple, Arvind Dev, Karen Anthony, Teresa Rodriguez Martin, Jean-Marc Gallo, Thomas A. Cooper
Publikováno v:
Human Molecular Genetics. 16:2760-2769
Elucidating the mechanisms of alternative splicing in the brain is a prerequisite to the understanding of the pathogenesis of major neurological diseases linked to impairment of pre-mRNA alternative splicing. The gene trinucleotide repeat-containing
Autor:
Thomas Haaf, Andreas Meinhardt, Nadja Drusenheimer, H. W. Michelmann, Kristina Rathsack, Wolfgang Engel, Ingrid Ehrmann, Ulrich Zechner, Gerald Wulf, Jae Ho Lee, Karim Nayernia, Jessica Nolte, David J. Elliott, Arvind Dev, Vera Okpanyi
Publikováno v:
Developmental Cell. 11:125-132
SummaryMale gametes originate from a small population of spermatogonial stem cells (SSCs). These cells are believed to divide infinitely and to support spermatogenesis throughout life in the male. Here, we developed a strategy for the establishment o
Autor:
Wolfgang Engel, Gregor Schlüter, Christian Müller, Detlef Böhm, Arvind Dev, Stephan Wolf, Karim Nayernia, Ibrahim M. Adham, Andreas Meinhardt, Özlem Topaloglu, Khailun Tseden
Publikováno v:
Molecular Reproduction and Development. 74:273-279
During mammalian spermiogenesis somatic histones are replaced at first by transition proteins, which are in turn replaced by the protamines, forming the sperm nucleoprotamines. It is believed that transition protein 2 (Tnp2) is necessary for maintain
Autor:
Ashley Johnson, Ruth Asch, Arvind Dev, Nicole Rainville, Edward Jachimowicz, Don M. Wojchowski, Emily Greenfest-Allen
Publikováno v:
Experimental Hematology. 49:48-55.e5
In response to anemia, the heightened production of erythropoietin (EPO) can sharply promote erythroid progenitor cell (EPC) formation. Specific mediators of such EPO- accelerated erythropoiesis, however, are not well understood. Presently, we first
Autor:
Melanie Ufkin, Pradeep Sathyanarayana, Anamika Pradeep, Don M. Wojchowski, Jonathan D. Licht, Arvind Dev
Publikováno v:
Blood. 119(23)
Sprouty proteins are established modifiers of receptor tyrosine kinase (RTK) signaling and play important roles in vasculogenesis, bone morphogenesis, and renal uteric branching. Little is understood, however, concerning possible roles for these mole
Autor:
Anamika Pradeep, Pradeep Sathyanarayana, Arvind Dev, Christine Emerson, Don M. Wojchowski, Jing Fang
Investigations of bone marrow (BM) erythroblast development are important for clinical concerns but are hindered by progenitor cell and tissue availability. We therefore sought to more specifically define dynamics, and key regulators, of the formatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f88ea73c9152b4863d710a3804f0a2
https://europepmc.org/articles/PMC3012546/
https://europepmc.org/articles/PMC3012546/
Autor:
Irakli Panchulidze, Moneef Shoukier, Ute Teske, Arvind Dev, Karim Nayernia, Loukas Argyriou, Johannes Wirbelauer
Publikováno v:
Swiss medical weekly. 138(29-30)
Hereditary haemorrhagic telangiectasia (HHT), associated with arteriovenous malformations, is a genetic disease of the vascular system with a frequency of approx. 1:10,000. Genetic diagnosis serves to identify individuals at risk of developing the di
Autor:
Sarah Browne, Arvind Dev, Madhu P. Menon, Jing Fang, Christine Emerson, Estelle Houde, Olga Bogacheva, Pradeep Sathyanarayana, Oleg Bogachev, Don M. Wojchowski, Anamika Pradeep
EPO functions primarily as an erythroblast survival factor, and its antiapoptotic actions have been proposed to involve predominantly PI3-kinase and BCL-X pathways. Presently, the nature of EPO-regulated survival genes has been investigated through t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c557199d9fd83bdeb5f3852fe3bb35b
https://europepmc.org/articles/PMC2396729/
https://europepmc.org/articles/PMC2396729/