Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Arvin M, Gouw"'
Autor:
Delaney K. Sullivan, Anja Deutzmann, Josiah Yarbrough, Maya S. Krishnan, Arvin M. Gouw, David I. Bellovin, Stacey J. Adam, Daniel F. Liefwalker, Renumathy Dhanasekaran, Dean W. Felsher
Publikováno v:
Oncogene. 41:4960-4970
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3eb64b45b6309a74b1576bf01221b33
https://doi.org/10.1038/s41388-022-02458-9
https://doi.org/10.1038/s41388-022-02458-9
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-5 (2017)
Externí odkaz:
https://doaj.org/article/074d71d5036b4a18bd4da6fc68944acc
Autor:
Dean W. Felsher, Amal C. Kataki, Jason R. Gotlib, Debabrat Baishya, Arvin M. Gouw, Gayatri Gogoi, Seema Bhuyan, Sorra Sandhya, Joyeeta Talukdar, Sukanya Gayan, Anupam Sarma, Hong Li, Rashmi Bhuyan, Bidisha Pal, Bikul Das
Supplemental Methods elaborate the details of each methodology/approaches being used in the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ae228e7d2dd0bc47efb6b138a26f6d
https://doi.org/10.1158/0008-5472.22422240
https://doi.org/10.1158/0008-5472.22422240
Autor:
Dean W. Felsher, Amal C. Kataki, Jason R. Gotlib, Debabrat Baishya, Arvin M. Gouw, Gayatri Gogoi, Seema Bhuyan, Sorra Sandhya, Joyeeta Talukdar, Sukanya Gayan, Anupam Sarma, Hong Li, Rashmi Bhuyan, Bidisha Pal, Bikul Das
Cancer stem cells (CSC) maintain both undifferentiated self-renewing CSCs and differentiated, non-self-renewing non-CSCs through cellular division. However, molecular mechanisms that maintain self-renewal in CSCs versus non-CSCs are not yet clear. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce3d73506ff769e9701c903d8f84d15f
https://doi.org/10.1158/0008-5472.c.6511164.v1
https://doi.org/10.1158/0008-5472.c.6511164.v1
Autor:
Arvin M. Gouw, Vineet Kumar, Angel Resendez, Fidelia B. Alvina, Natalie S. Liu, Katherine Margulis, Ling Tong, Richard N. Zare, Sanjay V. Malhotra, Dean W. Felsher
Publikováno v:
ACS Med Chem Lett
[Image: see text] A natural compound screen identified several anticancer compounds, among which azapodophyllotoxin (AZP) was found to be the most potent. AZP caused decreased viability of both mouse and human lymphoma and renal cell cancer (RCC) tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096a05acf95d728d93883951623e30a2
https://doi.org/10.1021/acsmedchemlett.1c00673
https://doi.org/10.1021/acsmedchemlett.1c00673
Autor:
Arvin M. Gouw, Aida S. Hansen, Wadie D. Mahauad-Fernandez, Renumathy Dhanasekaran, Anja Deutzmann, Dean W. Felsher
Publikováno v:
Nat Rev Clin Oncol
The MYC proto-oncogenes encode a family of transcription factors that are among the most commonly activated oncoproteins in human neoplasias. Indeed, MYC aberrations or upregulation of MYC-related pathways by alternate mechanisms occur in the vast ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c504f9d46b9ee4b387d91f449159f6a
https://doi.org/10.1038/s41571-021-00549-2
https://doi.org/10.1038/s41571-021-00549-2
Autor:
Yun Sheng Chen, Jianghong Rao, Weiping Zhu, Arvin M. Gouw, Jinghang Xie, Qihua Zhu, Zhi Yuan Wang, Leeann Hu, Liyang Cui, Elena A. Goun, Yao Tang, Ji Qi, Amato J. Giaccia, Zhou Gao, Dean W. Felsher, Shenghao Guo, Anne Le, Min Chen, Mingxi Fang, Kerriann M. Casey, Arkadiy A. Bazhin, Sanjiv S. Gambhir, Cissy Zhang, Nabeel Attarwala, Edward L. LaGory, Mark D. Pegram
Publikováno v:
Nature Biotechnology. 39:357-367
Depletion of mitochondrial copper, which shifts metabolism from respiration to glycolysis and reduces energy production, is known to be effective against cancer types that depend on oxidative phosphorylation. However, existing copper chelators are to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6da777b94c608142b78d36b356886a1
https://doi.org/10.1038/s41587-020-0707-9
https://doi.org/10.1038/s41587-020-0707-9
Autor:
Arvin M. Gouw
Publikováno v:
Zygon®. 55:421-429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a21ec60f5698b5e0f680387de8a0c1
https://doi.org/10.1111/zygo.12594
https://doi.org/10.1111/zygo.12594
Autor:
Arvin M. Gouw
Publikováno v:
Zygon®. 55:409-420
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1494f09162d3c3c28a258887a3a18537
https://doi.org/10.1111/zygo.12591
https://doi.org/10.1111/zygo.12591
Autor:
Delaney K, Sullivan, Anja, Deutzmann, Josiah, Yarbrough, Maya S, Krishnan, Arvin M, Gouw, David I, Bellovin, Stacey J, Adam, Daniel F, Liefwalker, Renumathy, Dhanasekaran, Dean W, Felsher
Publikováno v:
Oncogene. 41(45)
MYC is a transcription factor frequently overexpressed in cancer. To determine how MYC drives the neoplastic phenotype, we performed transcriptomic analysis using a panel of MYC-driven autochthonous transgenic mouse models. We found that MYC elicited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03c37dfedb08a373b20abd5bb39a508b
https://pubmed.ncbi.nlm.nih.gov/36207533
https://pubmed.ncbi.nlm.nih.gov/36207533