Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Arvid Berg"'
Autor:
Laeeq Ahmed, Hiba Alogheli, Staffan Arvidsson McShane, Jonathan Alvarsson, Arvid Berg, Anders Larsson, Wesley Schaal, Erwin Laure, Ola Spjuth
Publikováno v:
Journal of Cheminformatics, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Identifying and assessing ligand-target binding is a core component in early drug discovery as one or more unwanted interactions may be associated with safety issues. Contributions We present an open-source, extendable web service
Externí odkaz:
https://doaj.org/article/3cc3e6c22dfd49d4824bba59b083b156
Autor:
Maris Lapins, Staffan Arvidsson, Samuel Lampa, Arvid Berg, Wesley Schaal, Jonathan Alvarsson, Ola Spjuth
Publikováno v:
Journal of Cheminformatics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Lipophilicity is a major determinant of ADMET properties and overall suitability of drug candidates. We have developed large-scale models to predict water–octanol distribution coefficient (logD) for chemical compounds, aiding drug discover
Externí odkaz:
https://doaj.org/article/1d8de455ff4248958e66beecd6f355bf
Autor:
Egon L. Willighagen, John W. Mayfield, Jonathan Alvarsson, Arvid Berg, Lars Carlsson, Nina Jeliazkova, Stefan Kuhn, Tomáš Pluskal, Miquel Rojas-Chertó, Ola Spjuth, Gilleain Torrance, Chris T. Evelo, Rajarshi Guha, Christoph Steinbeck
Publikováno v:
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-19 (2017)
Abstract Background The Chemistry Development Kit (CDK) is a widely used open source cheminformatics toolkit, providing data structures to represent chemical concepts along with methods to manipulate such structures and perform computations on them.
Externí odkaz:
https://doaj.org/article/04d9c1e269724925b7979d21a9dd3f92
Autor:
Samuel Lampa, Jonathan Alvarsson, Staffan Arvidsson Mc Shane, Arvid Berg, Ernst Ahlberg, Ola Spjuth
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Ligand-based models can be used in drug discovery to obtain an early indication of potential off-target interactions that could be linked to adverse effects. Another application is to combine such models into a panel, allowing to compare and search f
Externí odkaz:
https://doaj.org/article/69edc0560ee242de9d5cbae1e83447ac
Autor:
Egon L. Willighagen, John W. Mayfield, Jonathan Alvarsson, Arvid Berg, Lars Carlsson, Nina Jeliazkova, Stefan Kuhn, Tomáš Pluskal, Miquel Rojas-Chertó, Ola Spjuth, Gilleain Torrance, Chris T. Evelo, Rajarshi Guha, Christoph Steinbeck
Publikováno v:
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-1 (2017)
Externí odkaz:
https://doaj.org/article/d29f0d164e91454a8645a5397063550f
Autor:
Ola Spjuth, Jonathan Alvarsson, Ernst Ahlberg, Staffan Arvidsson Mc Shane, Samuel Lampa, Arvid Berg
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
Ligand-based models can be used in drug discovery to obtain an early indication of potential off-target interactions that could be linked to adverse effects. Another application is to combine such models into a panel, allowing to compare and search f
Autor:
Tomáš Pluskal, Egon Willighagen, Miquel Rojas-Chertó, Lars Carlsson, John Mayfield, Rajarshi Guha, Ola Spjuth, Stefan Kuhn, Arvid Berg, Christoph Steinbeck, Nina Jeliazkova, Chris T. Evelo, gilleain torrance, Jonathan Alvarsson
Publikováno v:
Journal of Cheminformatics
Journal of Cheminformatics, 9:33. BioMed Central Ltd
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-19 (2017)
Journal of Cheminformatics, 9:33. BioMed Central Ltd
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-19 (2017)
Background The Chemistry Development Kit (CDK) is a widely used open source cheminformatics toolkit, providing data structures to represent chemical concepts along with methods to manipulate such structures and perform computations on them. The libra
Bioclipse-R: integrating management and visualization of life science data with statistical analysis
Autor:
Valentin Georgiev, Martin Eklund, Egon Willighagen, Jarl Es Wikberg, Ola Spjuth, Jonathan Alvarsson, Lars Carlsson, Arvid Berg
Publikováno v:
Bioinformatics
Bioinformatics, 29(2), 286-289. Oxford University Press
Bioinformatics, 29(2), 286-289. Oxford University Press
Summary: Bioclipse, a graphical workbench for the life sciences, provides functionality for managing and visualizing life science data. We introduce Bioclipse-R, which integrates Bioclipse and the statistical programming language R. The synergy betwe
Autor:
Martin Eklund, Egon Willighagen, Johannes Wagener, Jarl E. S. Wikberg, Jonathan Alvarsson, gilleain torrance, Christoph Steinbeck, Stefan Kuhn, Arvid Berg, Ola Spjuth, Carl Mäsak
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 397 (2009)
BMC Bioinformatics, 10:397. BioMed Central Ltd
BMC Bioinformatics
BMC Bioinformatics, 10:397. BioMed Central Ltd
BMC Bioinformatics
Background Contemporary biological research integrates neighboring scientific domains to answer complex questions in fields such as systems biology and drug discovery. This calls for tools that are intuitive to use, yet flexible to adapt to new tasks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87729253df7648f87e18aa07b5b2ea0
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-109304
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-109304
Autor:
Joern Fischer, Arvid Bergsten, Ine Dorresteijn, Jan Hanspach, Kristoffer Hylander, Tolera S. Jiren, Aisa O. Manlosa, Patricia Rodrigues, Jannik Schultner, Feyera Senbeta, Girma Shumi
Publikováno v:
Ecosystems and People, Vol 17, Iss 1, Pp 400-410 (2021)
We studied food security and biodiversity conservation from a social-ecological perspective in southwestern Ethiopia. Specialist tree, bird, and mammal species required large, undisturbed forest, supporting the notion of ‘land sparing’ for conser
Externí odkaz:
https://doaj.org/article/b0207f8991ea47ac84049afdd7a03619