Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Arvia E. Morris"'
Autor:
Brittney Livingston, Arvia E. Morris, Peter G. Slade, Lowell J. Brady, Robert Bailey, Craig Zupke, Lisa Taylor, Kyle Bigham, Philip Clark, R. Guy Caspary
Publikováno v:
Biotechnology Progress. 31:1433-1441
Pressures for cost-effective new therapies and an increased emphasis on emerging markets require technological advancements and a flexible future manufacturing network for the production of biologic medicines. The safety and efficacy of a product is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3cb3292918319646e789c2251510b5
https://doi.org/10.1002/btpr.2136
https://doi.org/10.1002/btpr.2136
Autor:
Chris B. Russell, Rebecca E. Mccoy, Arvia E. Morris, Dina Fomina-Yadlin, John J. Gosink, Brian D. Follstad, Jeffrey T. McGrew
Publikováno v:
Biotechnology and Bioengineering. 111:965-979
Depletion of two nonessential amino acids, asparagine (Asn) and glutamine (Gln), occurred during a fed-batch production process with a CHO cell line expressing a recombinant antibody. This depletion coincided with growth suppression and the onset of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3658e4daec4581332dbf5e3957526556
https://doi.org/10.1002/bit.25155
https://doi.org/10.1002/bit.25155
Autor:
Teri L. Aldrich, Frederick W. Jacobsen, Rupa Padaki, Taruna Arora, Martin J. Allen, Jennifer C. Lavallee, Richard J. Armitage, Arvia E. Morris
Publikováno v:
The Journal of Immunology. 186:341-349
Studies for vaccine and human therapeutic Ab development in cynomolgus monkeys (cynos) are influenced by immune responses, with Ab responses playing a significant role in efficacy and immunogenicity. Understanding the nature of cyno humoral immune re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3324005af018809c82555929b17153ec
https://doi.org/10.4049/jimmunol.1001685
https://doi.org/10.4049/jimmunol.1001685
Publikováno v:
Biotechnology Progress. 19:1433-1438
Over the past 10 years, monoclonal antibodies and antibody fragments have become an increasingly important source of therapeutic molecules in the biotechnology industry. Drug development strategies rely on screening large numbers of candidate molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac621e4e1ad31a5ce4974fef46bd08c8
https://doi.org/10.1021/bp034056j
https://doi.org/10.1021/bp034056j
Autor:
David Treiber, Brian D. Follstad, Zhimei Du, Yuling Zhang, Pranhitha Reddy, Brad Dell, Carole Heath, Dina Fomina-Yadlin, Ramsey A. Saleem, Arvia E. Morris, Craig Zupke, Matthew Leith, Brent Grisim, John D. McCarter, Rebecca E. Mccoy, Tharmala Tharmalingam
Publikováno v:
Biotechnology and Bioengineering
The continued need to improve therapeutic recombinant protein productivity has led to ongoing assessment of appropriate strategies in the biopharmaceutical industry to establish robust processes with optimized critical variables, that is, viable cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782a5dfaef3b9c854fc644324cd3702b
https://pubmed.ncbi.nlm.nih.gov/25042542
https://pubmed.ncbi.nlm.nih.gov/25042542
Autor:
Ralph Klinke, Richard L. Remmele, William C. Fanslow, Richard J. Armitage, Arvia E. Morris, Brian M. Macduff
Publikováno v:
Journal of Biological Chemistry. 274:418-423
Recent progress in the understanding of immune function indicates that the interaction of CD40L with its receptor, CD40, plays a pivotal role in both humoral immunity and cell-mediated defense against pathogens. Functional studies of this interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d865ae5442b2d0a658f3521ba987d909
https://doi.org/10.1074/jbc.274.1.418
https://doi.org/10.1074/jbc.274.1.418
Publikováno v:
Cytotechnology. 28:9-17
We have recently reported on the isolation of a 5.7 kb segment of Chinese hamster ovary cell genomic DNA, Expression Augmenting Sequence Element (EASE), which when used in bicistronic expression vectors allows the development of stable Chinese hamste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1de700c136384582c317679c1024316b
https://doi.org/10.1023/a:1008048807588
https://doi.org/10.1023/a:1008048807588
Autor:
Douglas E. Williams, Hilary J. McKenna, Chi Chang Lee, Kenneth Brasel, Stewart D. Lyman, Philip J. Morrissey, Arvia E. Morris, Keith Charrier
Publikováno v:
Blood. 88:2004-2012
We have investigated the effects of in vivo treatment with flt3 ligand (FL) on murine hematopoiesis, including mobilization of progenitors into the peripheral blood (PB). Mice were injected once daily with 10 micrograms recombinant human FL for 15 da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eae459c7f373dedca80493c6de00ca8
https://doi.org/10.1182/blood.v88.6.2004.bloodjournal8862004
https://doi.org/10.1182/blood.v88.6.2004.bloodjournal8862004
Autor:
Ralph Klinke, Arvia E. Morris, James E. Matsuura, Emory H. Braswell, Richard L. Remmele, Wayne R. Gombotz, Randal R. Ketchem
Publikováno v:
Archives of biochemistry and biophysics. 392(2)
The CD40 ligand molecule is unique, consisting of a receptor-binding domain anchored by an isoleucine zipper moiety. Exact determination of the multimeric state and its tendency to form molten globules has not been elucidated. Corroborating evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9ea08f9ee75d3a406dd218bf14de4f
https://pubmed.ncbi.nlm.nih.gov/11488594
https://pubmed.ncbi.nlm.nih.gov/11488594
Publikováno v:
Animal Cell Technology: From Target to Market ISBN: 9789401038973
As more genes are being identified through genomic techniques,the need to rapidly express recombinant proteins for functionalstudies has become increasingly acute. Transient expression ofrecombinant protein using COS-1, CV-1 and 293 cells is widelyus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c813144094e51a14a6e1a80b38d1a1f7
https://doi.org/10.1007/978-94-010-0369-8_9
https://doi.org/10.1007/978-94-010-0369-8_9
