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Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses

Autor: Racioppi, Luigi, Noeldner, Pamela K., Lin, Fumin, Arvai, Stephanie, Means, Anthony R.

Publikováno v: The Journal of biological chemistry. 287(14)

Calcium/calmodulin-dependent kinase kinase 2 (CaMKK2) plays a key role in regulating food intake and energy expenditure at least in part by its actions in hypothalamic neurons. Previously, we showed that loss of CaMKK2 protected mice from high-fat di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2cfac4325415d8ff842f4ca5d027dd
https://pubmed.ncbi.nlm.nih.gov/22334678

Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration

Autor: Luigi Racioppi, Jeffrey R. Harris, Nelson J. Chao, Yaping Liu, William Lento, Helder I. Nakaya, Stephanie Arvai, Wei Huang, Fernando Marcon, Phuong L. Doan

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell Death & Disease

Hematopoietic stem and progenitor cells (HSPCs) are predominantly quiescent in adults, but proliferate in response to bone marrow (BM) injury. Here, we show that deletion of Ca2+/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) promotes HS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b539e30da17bc9b6e675b213646e840
https://doi.org/10.1038/cddis.2017.474