Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Arup K, Indra"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Melanoma is the malignant transformation of melanocytes and represents the most lethal form of skin cancer. While early-stage melanoma localized to the skin can be cured with surgical excision, metastatic melanoma often requires a multi-pronged appro
Externí odkaz:
https://doaj.org/article/f248b1fc757d495fbb2a2f25b1fdcb2c
Autor:
Kelsey Pinkham, David Jaehyun Park, Arsalan Hashemiaghdam, Aleksandar B. Kirov, Isam Adam, Kamila Rosiak, Cintia C. da Hora, Jian Teng, Pike See Cheah, Litia Carvalho, Gitali Ganguli-Indra, Avalon Kelly, Arup K. Indra, Christian E. Badr
Publikováno v:
Stem Cell Reports, Vol 12, Iss 4, Pp 712-727 (2019)
Summary: Inherent plasticity and various survival cues allow glioblastoma stem-like cells (GSCs) to survive and proliferate under intrinsic and extrinsic stress conditions. Here, we report that GSCs depend on the adaptive activation of ER stress and
Externí odkaz:
https://doaj.org/article/9886afc7efdb4b3aba3936f75349e152
Publikováno v:
Cells, Vol 11, Iss 13, p 2106 (2022)
Transcriptional regulator BCL11A plays a crucial role in coordinating a suite of developmental processes including skin morphogenesis, barrier functions and lipid metabolism. There is little or no reports so far documenting the role of BCL11A in post
Externí odkaz:
https://doaj.org/article/7a4e4c96733143afa898f9caaa74a5a4
Autor:
Sharmeen Chagani, Rong Wang, Evan L. Carpenter, Christiane V. Löhr, Gitali Ganguli-Indra, Arup K. Indra
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Understanding the underlying molecular mechanisms involved in the formation of cutaneous malignant melanoma is critical for improved diagnosis and treatment. Keratinocytic nuclear receptor Retinoid X Receptor α (RXRα) has a prot
Externí odkaz:
https://doaj.org/article/7e25df122d754e87b799ae02f27491f5
Autor:
Arup K. Indra, Gitali Ganguli-Indra, Xiaobo Liang, Christiane V. Löhr, Anna M. Sherman, Stephen Hyter, Sharmeen Chagani, Daniel J. Coleman
Antibodies used for experiments. Supplementary Table S2: PCR primers used for genotyping of mouse lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e12fd1dc54d0add7dd476606c56097
https://doi.org/10.1158/1541-7786.22511842
https://doi.org/10.1158/1541-7786.22511842
Autor:
Arup K. Indra, Gitali Ganguli-Indra, Xiaobo Liang, Christiane V. Löhr, Anna M. Sherman, Stephen Hyter, Sharmeen Chagani, Daniel J. Coleman
Supplementary Figure S5: No change in infiltrating mast cells as determined by CEM staining is observed in melanocytic lesions from either Cdk4R24c or Tyr-NRASQ61K mice with epidermis-specific knockout of Rxra. Assay was performed on bleached 5 J.lm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b17be80a208afd6561b90819a2f7004
https://doi.org/10.1158/1541-7786.22511860
https://doi.org/10.1158/1541-7786.22511860
Autor:
Arup K. Indra, Gitali Ganguli-Indra, Xiaobo Liang, Christiane V. Löhr, Anna M. Sherman, Stephen Hyter, Sharmeen Chagani, Daniel J. Coleman
Supplementary Figure S8: Chronically UVB-irradiated tumor-adjacent normal skin from Tyr-NRASQBtK or Cdk4R24c mice with epidermis-specific knockout of Rxra show modest increase in CDK4 expression; downregulation of phosphorylated ERK, as well as incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106776c5f06c502b5bd4260d274f1370
https://doi.org/10.1158/1541-7786.22511851
https://doi.org/10.1158/1541-7786.22511851
Autor:
Arup K. Indra, Gitali Ganguli-Indra, Xiaobo Liang, Christiane V. Löhr, Anna M. Sherman, Stephen Hyter, Sharmeen Chagani, Daniel J. Coleman
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc3bebffdcadb0db11d199714cae31e
https://doi.org/10.1158/1541-7786.22511848.v1
https://doi.org/10.1158/1541-7786.22511848.v1
Autor:
Arup K. Indra, Gitali Ganguli-Indra, Xiaobo Liang, Christiane V. Löhr, Anna M. Sherman, Stephen Hyter, Sharmeen Chagani, Daniel J. Coleman
Supplementary Figure S2: Chronic-UVB treated and parallel non-treated controls used in this study. (A,B) H&E staining of non-UVB treated skin from parallel age-matched mice (A) and TAN skin from chronic-UVB treated mice (B). In all groups, TAN skin h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25eea61082a303a4b34a0dbd09068fe7
https://doi.org/10.1158/1541-7786.22511869.v1
https://doi.org/10.1158/1541-7786.22511869.v1
Autor:
Arup K. Indra, Gitali Ganguli-Indra, Xiaobo Liang, Christiane V. Löhr, Anna M. Sherman, Stephen Hyter, Sharmeen Chagani, Daniel J. Coleman
Supplementary Figure S1: Breeding/Genotyping of mouse lines used in this study. (A, B) Breeding crossings used. K14-Cre'g/O I RxraL2/L2 is also known as RXRaep-/-. (C) Semi-quantitative PCR was performed on biopsies containing both epidermal and non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17da816135d8fb2fdf5376584e52003
https://doi.org/10.1158/1541-7786.22511872
https://doi.org/10.1158/1541-7786.22511872