Výsledky vyhledávání - "Arunnjah Vivekanandarajah"

Akademický článek

Nicotinic Receptors in the Brainstem Ascending Arousal System in SIDS With Analysis of Pre-natal Exposures to Maternal Smoking and Alcohol in High-Risk Populations of the Safe Passage Study

Publikováno v: Frontiers in Neurology, Vol 12 (2021)

Pre-natal exposures to nicotine and alcohol are known risk factors for sudden infant death syndrome (SIDS), the leading cause of post-neonatal infant mortality. Here, we present data on nicotinic receptor binding, as determined by 125I-epibatidine re

Externí odkaz: https://doaj.org/article/5ba97428e4464cd2b394a82641af6085

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Cell death in the lateral geniculate nucleus, and its possible relationship with nicotinic receptors and sudden infant death syndrome (SIDS)

Autor: Cynthia Chang, Arunnjah Vivekanandarajah, Karen A Waters, Rita Machaalani

Publikováno v: Molecular Neurobiology. 60:4120-4131

The role of the lateral geniculate nucleus (LGN) in vision has been extensively studied, yet its extraretinal capacities are still being investigated, including its role in arousal from sleep. The β2 nicotinic acetylcholine receptor (nAChR) subunit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1087c5b3c0135154211cb73f03f0dba
https://doi.org/10.1007/s12035-023-03332-9

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Expression of reelin with age in the human hippocampal formation

Autor: Karen A. Waters, Vanessa Despotovski, Arunnjah Vivekanandarajah, Rita Machaalani

Publikováno v: Hippocampus. 31:493-502

Reelin plays a key role in neuronal migration and lamination in the cortex and hippocampus. Animal studies have shown that reelin expression decreases with age. The aim of this study was to evaluate the expression of reelin in all layers of the human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddff4f64628d8e91687d0e2ef103112
https://doi.org/10.1002/hipo.23310

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Morphology of the Dentate Gyrus in a Large Cohort of Sudden Infant Deaths-Interrelation Between Features but Not Diagnosis

Autor: Rita Machaalani, Arunnjah Vivekanandarajah, Vanessa Despotovski, Michael Rodriguez, Karen A Waters

Publikováno v: Journal of neuropathology and experimental neurology. 81(1)

Morphological differences in the dentate gyrus (DG) have been reported in sudden unexpected deaths in infancy (SUDI), with the feature of focal granule cell (GC) bilamination (FGCB) reported as increased in unexplained SUDI, including sudden infant d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa841e7d36b4e2544e00d8f4db116ec
https://pubmed.ncbi.nlm.nih.gov/34865047

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Cigarette smoke exposure effects on the brainstem expression of nicotinic acetylcholine receptors (nAChRs), and on cardiac, respiratory and sleep physiologies

Autor: Arunnjah Vivekanandarajah, Rita Machaalani, Karen A. Waters

Publikováno v: Respiratory Physiology & Neurobiology. 259:1-15

Cigarette smoking during pregnancy is the largest modifiable risk factor for adverse outcomes in the infant. Investigations have focused on the psychoactive component of cigarettes, nicotine. One proposed mechanism leading to adverse effects is the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edbeb150b63f186cbdbc79472f6f3d1
https://doi.org/10.1016/j.resp.2018.07.007

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The α7 and β2 nicotinic acetylcholine receptor subunits regulate apoptosis in the infant hippocampus, and in sudden infant death syndrome (SIDS)

Autor: Karen A. Waters, Rita Machaalani, Arunnjah Vivekanandarajah, L. L. M. Luijerink

Publikováno v: Apoptosis : an international journal on programmed cell death. 25(7-8)

Apoptosis is increased in the hippocampus of infants who died of sudden infant death syndrome (SIDS), yet it is not known via which mechanism this has occurred. Following existing support for a role of the α7 and β2 nicotinic acetylcholine receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534cabad57490f55458ac5f8e1efe178
https://pubmed.ncbi.nlm.nih.gov/32577853

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Intermittent hypercapnic hypoxia effects on the nicotinic acetylcholine receptors in the developing piglet hippocampus and brainstem

Autor: Atqiya Aishah, Arunnjah Vivekanandarajah, Karen A. Waters, Rita Machaalani

Publikováno v: NeuroToxicology. 60:23-33

This study investigated the effects of acute (1 day) vs repeated (4 days) exposure to intermittent hypercapnic hypoxia (IHH) on the immunohistochemical expression of α2, α3, α5, α7, α9 and β2 nicotinic acetylcholine receptor (nAChR) subunits in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09574d853344e33a12e1b097e0cec43e
https://doi.org/10.1016/j.neuro.2017.02.011

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Postnatal nicotine effects on the expression of nicotinic acetylcholine receptors in the developing piglet hippocampus and brainstem

Autor: Karen A. Waters, Arunnjah Vivekanandarajah, Rita Machaalani

Publikováno v: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 47

Postnatal exposure to cigarette smoke during infancy is associated with increased number of respiratory illnesses, impaired pulmonary function, and the occurrence of Sudden Infant Death Syndrome (SIDS). It is also associated with reduced cognitive fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53bc45bf006651580b2e706b66b8198
https://pubmed.ncbi.nlm.nih.gov/26440997

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