Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Arunima Sakunthala"'
Autor:
Pratiksha P. Deshmukh, Gauri S. Malankar, Arunima Sakunthala, Ambuja Navalkar, Samir K. Maji, Dhiraj P. Murale, Raju Saravanan, Sudesh T. Manjare
Publikováno v:
Dalton Transactions. 51:2269-2277
A coumarin based turn-on sensor for the selective detection of Hg(ii) through oxidation of diselenide. The sensing mechanism supported with single crystal XRD of monoselenide. Sensitivity of the probe for the detection of Hg(ii) confirmed with imagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0fe87e67b13ec0cda7d0201a96970cd
https://doi.org/10.1039/d1dt04038c
https://doi.org/10.1039/d1dt04038c
Publikováno v:
Essays in biochemistry. 66(7)
α-Synuclein (α-Syn) is a natively unstructured protein, which self-assembles into higher-order aggregates possessing serious pathophysiological implications. α-Syn aberrantly self-assembles into protein aggregates, which have been widely implicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9652cf96b99405304d7f10571df3d037
https://pubmed.ncbi.nlm.nih.gov/36373662
https://pubmed.ncbi.nlm.nih.gov/36373662
Autor:
Ambuja Navalkar, Ajoy Paul, Arunima Sakunthala, Satyaprakash Pandey, Amit Kumar Dey, Sandhini Saha, Sarthak Sahoo, Mohit Kumar Jolly, Tushar K. Maiti, Samir K. Maji
Publikováno v:
Journal of Cell Science. 135
Transcription factor p53 (also known as TP53) has been shown to aggregate into cytoplasmic and nuclear inclusions, compromising its native tumor suppressive functions. Recently, p53 has been shown to form amyloids, which play a role in conferring can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40826d10128dceb50bbc2b633b340966
https://doi.org/10.1242/jcs.259500
https://doi.org/10.1242/jcs.259500
Autor:
Arunima Sakunthala, Debalina Datta, Ambuja Navalkar, Laxmikant Gadhe, Pradeep Kadu, Komal Patel, Surabhi Mehra, Rakesh Kumar, Debdeep Chatterjee, Jyoti Devi, Kundan Sengupta, Ranjith Padinhateeri, Samir K. Maji
Publikováno v:
The journal of physical chemistry letters. 13(28)
The size of amyloid seeds is known to modulate their autocatalytic amplification and cellular toxicity. However, the seed size-dependent secondary nucleation mechanism, toxicity, and disease-associated biological processes mediated by α-synuclein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b84168db49a0487cddd30253f878e3
https://pubmed.ncbi.nlm.nih.gov/35816132
https://pubmed.ncbi.nlm.nih.gov/35816132
Autor:
Surabhi Mehra, Sahil Ahlawat, Harish Kumar, Debalina Datta, Ambuja Navalkar, Nitu Singh, Komal Patel, Laxmikant Gadhe, Pradeep Kadu, Rakesh Kumar, Narendra N. Jha, Arunima Sakunthala, Ajay S. Sawner, Ranjith Padinhateeri, Jayant B. Udgaonkar, Vipin Agarwal, Samir K. Maji
Publikováno v:
Journal of molecular biology. 434(19)
α-Synuclein (α-Syn) amyloids in synucleinopathies are suggested to be structurally and functionally diverse, reminiscent of prion-like strains. The mechanism of how the aggregation of the same precursor protein results in the formation of fibril po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cc7b9e11fe89557607e75dffa3a59a
https://pubmed.ncbi.nlm.nih.gov/35907572
https://pubmed.ncbi.nlm.nih.gov/35907572
Autor:
Semanti Mukherjee, Arunima Sakunthala, Laxmikant Gadhe, Manisha Poudyal, Ajay Singh Sawner, Pradeep Kadu, Samir K. Maji
Publikováno v:
Journal of Molecular Biology. 435:167713
Aberrant aggregation of the misfolded presynaptic protein, α-Synuclein (α-Syn) into Lewy body (LB) and Lewy neuritis (LN) is a major pathological hallmark of Parkinson's disease (PD) and other synucleinopathies. Numerous studies have suggested that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65140276ec93dd54bf1660faa4e4e104
https://doi.org/10.1016/j.jmb.2022.167713
https://doi.org/10.1016/j.jmb.2022.167713
Akademický článek
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Autor:
Arunima Sakunthala, Debalina Datta, Ambuja Navalkar, Laxmikant Gadhe, Pradeep Kadu, Komal Patel, Surabhi Mehra, Rakesh Kumar, Debdeep Chatterjee, Kundan Sengupta, Ranjith Padinhateeri, Samir K. Maji
The size of the amyloid seeds is known to modulate their autocatalytic amplification and cellular toxicity. However, the seed size-dependent secondary nucleation mechanism, toxicity, and disease-associated biological processes mediated by α-synuclei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2efadef4fb338fdb528a48804e238187
https://doi.org/10.1101/2021.12.28.474324
https://doi.org/10.1101/2021.12.28.474324
Autor:
Laxmikant Gadhe, Arunima Sakunthala, Semanti Mukherjee, Nitisha Gahlot, Riya Bera, Ajay Singh Sawner, Pradeep Kadu, Samir K. Maji
Publikováno v:
Biophysical chemistry. 281
Cytoplasmic deposition of aberrantly misfolded α-synuclein (α-Syn) is a common feature of synucleinopathies, including Parkinson's disease (PD). However, the precise pathogenic mechanism of α-Syn in synucleinopathies remains elusive. Emerging evid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c42a8da28ff9ba50fc9101705e8845
https://pubmed.ncbi.nlm.nih.gov/34923391
https://pubmed.ncbi.nlm.nih.gov/34923391
Autor:
Gauri S. Malankar, Samir K. Maji, Ambuja Navalkar, Saravanan Raju, Arunima Sakunthala, Sudesh T. Manjare
Publikováno v:
Analytica chimica acta. 1150
Phenylselenide substituted BOPHY probes (BOPHY-SePh and PhSe-BOPHY-SePh) were synthesized and characterized by NMR spectroscopy and single-crystal XRD. Both the probes selectively detect HOCl in water with high sensitivity over other reactive oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6587c5d94c8812feaa777747a25fe44
https://pubmed.ncbi.nlm.nih.gov/33583549
https://pubmed.ncbi.nlm.nih.gov/33583549