Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Arunima Choudhary"'
Autor:
Thanh Quang Nguyen, Bo Eun Heo, Yujin Park, Seunghyeon Jeon, Arunima Choudhary, Cheol Moon, Jichan Jang
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT There is an unmet medical need for effective treatments against Mycobacterium abscessus infections. Although advanced molecular genetic tools to validate drug targets and resistance of M. abscessus exist, the practical design and constructio
Externí odkaz:
https://doaj.org/article/f71c57ac71f948f7993a270537292da2
Autor:
Thanh Quang Nguyen, Bo Eun Heo, Bui Thi Bich Hanh, Seunghyeon Jeon, Yujin Park, Arunima Choudhary, Sujin Lee, Tae Ho Kim, Cheol Moon, Sun-Joon Min, Jichan Jang
Publikováno v:
Antimicrobial Agents and Chemotherapy.
Benzoxaboroles are a new class of leucyl-tRNA synthetase inhibitors. Epetraborole, a benzoxaborole, is a clinical candidate developed for Gram-negative infections and has been confirmed to exhibit favorable activity against a well known pulmonary pat
Autor:
Thanh Quang Nguyen, Bui Thi Bich Hanh, Seunghyeon Jeon, Bo Eun Heo, Yujin Park, Arunima Choudhary, Cheol Moon, Jichan Jang
Publikováno v:
Antimicrob Agents Chemother
Q203 is a first-in-class drug candidate against Mycobacterium tuberculosis. In its recently completed phase 2 clinical trial, Q203 reduced the number of live M. tuberculosis cells in a dose-dependent manner. This orally active small molecule blocks M