Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Arunasalam Navaraj"'
Autor:
Wafik S. El-Deiry, Anil K. Rustgi, Andres J.P. Klein-Szanto, Yoshio Naomoto, Arunasalam Navaraj, Hiroshi Nakagawa, Seok-Hyun Kim
Supplementary Figure and Movie Legends from Tumorigenic Conversion of Primary Human Esophageal Epithelial Cells Using Oncogene Combinations in the Absence of Exogenous Ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2297eab73db69e4c7d65837cf25700c1
https://doi.org/10.1158/0008-5472.22366236.v1
https://doi.org/10.1158/0008-5472.22366236.v1
Autor:
Wafik S. El-Deiry, Noboru Motoyama, Kazuyoshi Takeda, Hideo Yagita, George Cerniglia, Krystle A. Lang Kuhs, Arunasalam Navaraj, Prashanth Gokare, Niklas K. Finnberg
Supplemental Material & Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079147bf6b18a334240d55f035b5c7e7
https://doi.org/10.1158/0008-5472.22409744
https://doi.org/10.1158/0008-5472.22409744
Autor:
Wafik S. El-Deiry, Anil K. Rustgi, Andres J.P. Klein-Szanto, Yoshio Naomoto, Arunasalam Navaraj, Hiroshi Nakagawa, Seok-Hyun Kim
To investigate pathways of human esophageal squamous cell transformation, we generated esophageal tumor cells using human telomerase– and SV40-immortalized primary esophageal epithelial cells (EPC2) by overexpression of selected combinations of onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d6ab501ff91b23e33f7e9e1e4513e4
https://doi.org/10.1158/0008-5472.c.6495048
https://doi.org/10.1158/0008-5472.c.6495048
Autor:
Wafik S. El-Deiry, Noboru Motoyama, Kazuyoshi Takeda, Hideo Yagita, George Cerniglia, Krystle A. Lang Kuhs, Arunasalam Navaraj, Prashanth Gokare, Niklas K. Finnberg
The combination of TRAIL death receptor agonists and radiochemotherapy to treat advanced cancers continues to be investigated in clinical trials. We previously showed that normal cells with a functional DNA damage response (DDR) upregulate the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee93db091df99a63ee979793fd780c6
https://doi.org/10.1158/0008-5472.c.6507845.v1
https://doi.org/10.1158/0008-5472.c.6507845.v1
Autor:
Wafik S. El-Deiry, Anil K. Rustgi, Andres J.P. Klein-Szanto, Yoshio Naomoto, Arunasalam Navaraj, Hiroshi Nakagawa, Seok-Hyun Kim
Supplementary Movie from Tumorigenic Conversion of Primary Human Esophageal Epithelial Cells Using Oncogene Combinations in the Absence of Exogenous Ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb8ca55fc1b53c5833579684b557ab6
https://doi.org/10.1158/0008-5472.22366230.v1
https://doi.org/10.1158/0008-5472.22366230.v1
Autor:
Wafik S. El-Deiry, Anil K. Rustgi, Andres J.P. Klein-Szanto, Yoshio Naomoto, Arunasalam Navaraj, Hiroshi Nakagawa, Seok-Hyun Kim
Supplementary Figures 1-2, Tables 1-2 from Tumorigenic Conversion of Primary Human Esophageal Epithelial Cells Using Oncogene Combinations in the Absence of Exogenous Ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7123c2876576f1b5b2ed08c7d54ea2f6
https://doi.org/10.1158/0008-5472.22366233
https://doi.org/10.1158/0008-5472.22366233
Autor:
Wafik S. El-Deiry, Noboru Motoyama, Kazuyoshi Takeda, Hideo Yagita, George Cerniglia, Krystle A. Lang Kuhs, Arunasalam Navaraj, Prashanth Gokare, Niklas K. Finnberg
Supplementary Figure Legends for Supplementary Figures 1-9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d190293107209fd5216bb45fc16cf460
https://doi.org/10.1158/0008-5472.22409741
https://doi.org/10.1158/0008-5472.22409741
Autor:
Wafik S. El-Deiry, Noboru Motoyama, Kazuyoshi Takeda, Hideo Yagita, George Cerniglia, Krystle A. Lang Kuhs, Arunasalam Navaraj, Prashanth Gokare, Niklas K. Finnberg
Supplementary Figures 1-9. Sup. Fig. 1: IV injections of the monoclonal DR5-targeting MD5-1 antibody in combination with fluorouracil (5-FU) and CPT-11 sensitizes mice to chemotherapy-induced toxicity. Area-under-the curve (AUC) analysis of weight lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661292a084020f234bf4f5263b2aaebc
https://doi.org/10.1158/0008-5472.22409738
https://doi.org/10.1158/0008-5472.22409738
Autor:
Arunasalam Navaraj, Eric A. Ross, Seul Ki Lee, Young Lee, Aakash Jhaveri, Lanlan Zhou, Marie D. Ralff, Benedito A. Carneiro, Howard Safran, Varun V. Prabhu, Wafik S. El-Deiry
Publikováno v:
Cancer Biology & Therapy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The five-year survival rate for pancreatic ductal adenocarcinoma (PDAC) has remained a dismal 9% for approximately 40 years with an urgent need for novel therapeutic interventions. ONC201 is the founding member of the imipridone class, comprised of o
Autor:
Wafik S. El-Deiry, Andrew George, Francesca Di Cristofano, Praveen Srinivasan, Lindsey Carlsen, Kelsey E. Huntington, Arielle De La Cruz, Leiqing Zhang, Marina Hahn, Shuai Zhao, Attila Seyhan, Bradley D. DeNardo, Aaron W. Maxwell, Dae Hee Kim, Alex Raufi, Hina Khan, Stephanie L. Graff, Don S. Dizon, Christopher Azzoli, Abbas E. Abbas, Roxanne Wood, Rishi R. Lulla, Howard P. Safran, Benedito A. Carneiro, Arunasalam Navaraj, Xiaobing Tian, Shengliang Zhang, Lanlan Zhou
Publikováno v:
Cancer Research. 83:4185-4185
Our Laboratory was established in 1994 at Univ. of Pennsylvania. Lab members demonstrated initial competencies by performing cell culture, western blots, immunofluorescence, and flow cytometry showing induction of p53/p21(WAF1) in cells treated with