Výsledky vyhledávání - "Arunansu Dasgupta"

Cellular Immune Response against Tropomyosin Isoform 5 in Ulcerative Colitis

Autor: Kenneth D. Glazier, Xin Geng, Masato Taniguchi, Arunansu Dasgupta, Kiron M. Das, Jim J.-C. Lin

Publikováno v: Clinical Immunology. 101:289-295

We have reported an autoantibody response in ulcerative colitis (UC) against human tropomyosin isoform 5 (hTM5), the predominant colonic epithelial cell hTM isoform. In this report, we determined the number of IFN-gamma-secreting cells (spot-forming

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c731bf786b9ec9527a4e85a65d2ca5e0
https://doi.org/10.1006/clim.2001.5133

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Oral administration of unmodified colonic but not small intestinal antigens protects rats from hapten-induced colitis

Autor: K. V. Kesari, Arunansu Dasgupta, Kiron M. Das, K. Ramaswamy, Peter S. Amenta

Publikováno v: Clinical and Experimental Immunology. 125:41-47

SummaryColonic administration of a hapten, 2,4,6-trinitrobenzene sulphonic acid (TNBS) has been shown to induce colitis in rats. We are using this model to investigate the role of colonic antigens in the immunopathology. In this study, we show that c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190b26dd12560dde4b4fe645fd8bf1c6
https://doi.org/10.1046/j.1365-2249.2001.01539.x

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Development of Ulcerative Colitis-Associated Anti-Idiotype Antibody Using a Novel Monoclonal Antibody against a Colonic Autoantigen

Autor: Urvish Shah, Kiron M. Das, Arunansu Dasgupta

Publikováno v: Cellular Immunology. 166:154-157

Earlier studies have established reactivity of ulcerative colitis colon-bound IgG antibody with an autoantigen recognized by a novel monoclonal antibody, 7E12H12(IgM isotype). Purified 7E12H12-IgM was used to raise anti-idiotype antibody in the rabbi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274c4c30b3f45c6542e8a5311b5c1208
https://doi.org/10.1006/cimm.1995.0017

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Colon epithelial cellular protein induces oral tolerance in the experimental model of colitis by trinitrobenzene sulfonic acid

Autor: Arunansu Dasgupta, Peter S. Amenta, Jorge Giraldo, Masato Taniguchi, K. Ramaswamy, Kiron M. Das

Publikováno v: The Journal of laboratory and clinical medicine. 138(4)

Rectal administration of trinitrobenzene sulfonic acid (TNBS) produces chronic co-litis in experimental animals. However, the role of epithelial cellular protein(s) in this model is unknown. We examined whether oral tolerance can be induced in this m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d972f0cc8e0b6751ad0022800ab637
https://pubmed.ncbi.nlm.nih.gov/11574820

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Tropomyosin isoforms in intestinal mucosa: production of autoantibodies to tropomyosin isoforms in ulcerative colitis

Autor: Kiron M. Das, Arunansu Dasgupta, Xin Geng, Francesco Pallone, Hui Hui Dai, J.J-C. Lin§, Livia Biancone, Naohito Yoshizaki

Publikováno v: Gastroenterology. 114(5)

Autoantibodies against tropomyosins (TMs) have been reported in ulcerative colitis (UC). In this study the hTM isoforms (hTM1-5) present in intestinal epithelial cells and in smooth muscle were investigated, and the immunoreactivity against hTMs by i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6cee49862cfa77f7ac760cbabf68d9
https://pubmed.ncbi.nlm.nih.gov/9558279

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Autoantibodies in sclerosing cholangitis against a shared peptide in biliary and colon epithelium

Autor: Linda Squillante, Rajender Reddy, Eugene R. Schiff, Jeffers Lj, Aditya Mandal, Arunansu Dasgupta, Kiron M. Das, Shakir A. Hyder

Publikováno v: Gastroenterology. 106(1)

Background/Aims: A strong association exists between ulcerative colitis and primary sclerosing cholangitis (PSC). Previously, the presence of a unique epitope shared by colon and biliary epithelial cells was shown by using the novel monoclonal antibo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40fba232c79c4f708f6c358a11f19ba
https://pubmed.ncbi.nlm.nih.gov/7506217

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