Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Arunachalam, Muthuraman"'
Autor:
Arunachalam Muthuraman, Abu Sadat Md. Sayem, Sakthiganapathi Meenakshisundaram, Nemat Ali, Sheikh F. Ahmad, Abdullah F. AlAsmari, Shamama Nishat, Khian Giap Lim, Yamunna Paramaswaran
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2654 (2023)
Indoxyl sulfate (IS) is a metabolic byproduct of indole metabolism. IS readily interacts with the mitochondrial redox metabolism, leading to altered renal function. The β-carotene oxygenase-2 (BCO2) enzyme converts carotenoids to intermediate produc
Externí odkaz:
https://doaj.org/article/6eafa1b1d832433bb5a4fb15f352492f
Autor:
Nallupillai Paramakrishnan, Khian Giap Lim, Yamunna Paramaswaran, Nemat Ali, Mohammad Waseem, Gamal A. Shazly, Yousef A. Bin Jardan, Arunachalam Muthuraman
Publikováno v:
Marine Drugs, Vol 21, Iss 8, p 433 (2023)
Alzheimer’s disease (AD) is a major type of dementia disorder. Common cognitive changes occur as a result of cerebrovascular damage (CVD) via the disruption of matrix metalloproteinase-13 (MMP-13). In diabetic cases, the progress of vascular dement
Externí odkaz:
https://doaj.org/article/594fbc30e9b8477b9c98720c28d07e44
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 828 (2023)
Neurovascular dysfunction leads to the second most common type of dementia, i.e., vascular dementia (VaD). Toxic metals, such as aluminium, increase the risk of neurovascular dysfunction-associated VaD. Hence, we hypothesized that a natural antioxida
Externí odkaz:
https://doaj.org/article/7565f1511baa43539624bfe215e957b0
Autor:
Arunachalam Muthuraman, Muthusamy Ramesh, Fazlina Mustaffa, Ahmed Nadeem, Shamama Nishat, Nallupillai Paramakrishnan, Khian Giap Lim
Publikováno v:
Molecules, Vol 28, Iss 11, p 4358 (2023)
Molecular docking is widely used in the assessment of the therapeutic potential of pharmaceutical agents. The binding properties of beta-carotene (BC) to acetylcholine esterase (AChE) proteins were characterized using the molecular docking method. Th
Externí odkaz:
https://doaj.org/article/f9ba9dc8fc3b4422b9813dec856015cd
Autor:
Yamunna Paramaswaran, Aswinprakash Subramanian, Nallupillai Paramakrishnan, Muthusamy Ramesh, Arunachalam Muthuraman
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 647 (2023)
Diabetic retinopathy (DR) primarily progresses into retinal degeneration caused by microvascular dysfunction. The pathophysiology of DR progression is still uncertain. This study investigates the function of beta-carotene (PBC) originating from palm
Externí odkaz:
https://doaj.org/article/aabf35f3823b47c19424a3d6ede1c8da
Autor:
Sumeet Kumar Singla, Arunachalam Muthuraman, Diksha Sahai, Naveen Mangal, Jagadeesh Dhamodharan
Publikováno v:
Frontiers in Bioscience-Elite, Vol 13, Iss 1, Pp 158-184 (2020)
Transdermal drug-delivery systems (TDDS) offer an attractive alternative to the oral route for delivery of biotherapeutics. Technological advancements in the past few decades have revolutionized the fabrication of micro-structured devices including c
Externí odkaz:
https://doaj.org/article/5933bd97e75d4616bcc61757eed03c42
Publikováno v:
Frontiers in Bioscience-Elite, Vol 12, Iss 1, Pp 79-94 (2020)
Vascular dementia (VaD) refers to the loss of reasoning, planning, judgment, and memory as a result of reduced blood flow, inflammation, activation of immune cells, and neurodegenerative processes. Here, we tested the preventive effects of alpha-naph
Externí odkaz:
https://doaj.org/article/64825c5b4366461abf336b1394b6a5ab
Autor:
Nallupillai Paramakrishnan, Laxmikant Chavan, Khian Giap Lim, Yamunna Paramaswaran, Arunachalam Muthuraman
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 157 (2023)
Beta carotene is a natural anti-oxidant agent, and it inhibits the matrix metalloprotease (MMP) activity. Diabetic neuropathic pain (DNP) is produced by cellular oxidative stress. The role of the beta carotene effect in diabetic neuropathic pain is n
Externí odkaz:
https://doaj.org/article/9de411cc221e4930ac9bc26646249134
Autor:
Satbir Kaur, Arunachalam Muthuraman
Publikováno v:
Toxicology Reports, Vol 6, Iss , Pp 505-513 (2019)
The present study has been investigated the role of gallic acid (GA) in paclitaxel-induced neuropathic pain. The neuropathic pain was developed with paclitaxel (PT: 2 mg/kg, i.p.) administration in mice. GA (20 and 40 mg/kg) and pregabalin (PreG: 5 m
Externí odkaz:
https://doaj.org/article/cbd021f696f0470d8928bb890eaf6cd1
Publikováno v:
Molecules, Vol 27, Iss 16, p 5182 (2022)
Alzheimer’s disease (AD) is one of the major neurodegenerative disorders, and its incidence increases globally every year. Currently, available AD drugs symptomatically treat AD with multiple adverse effects. Gefitinib (GE) is an epidermal growth f
Externí odkaz:
https://doaj.org/article/1c14904eaea84cc59438f3137a965a37