Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aruna Koganti"'
Autor:
Michael K. McMillian, Cis Van Looveren, Paul M. Silber, Willem Meuldermans, Aruna Koganti, J. Brandon Parker, Mark D. Johnson, Ron A. H. J. Gilissen, Angelique Leone, Geert Mannens, Dirk Roymans
Publikováno v:
Biochemical Pharmacology. 67:427-437
Freshly prepared human hepatocytes are considered as the 'gold standard' for in vitro testing of drug candidates. However, several disadvantages are associated with the use of this model system. The availability of hepatocytes is often low and conseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97362dba061025ad0c1e1678858be8be
https://doi.org/10.1016/j.bcp.2003.09.022
https://doi.org/10.1016/j.bcp.2003.09.022
Autor:
Eric H. Weyand, Aruna Koganti, Kimberly Rozett, Nehal Modi, Renu Singh, Lawrence S. Goldstein, Fang Jie Zhang, Ronald G. Harvey, Tim A. Roy
Publikováno v:
Carcinogenesis. 21:1601-1609
Coal tar is a complex mixture that exhibits high carcinogenic potency in lungs of animals when administered in the diet. Studies have noted that lung tumor induction does not correlate with the benzo[a]pyrene content of coal tar, suggesting that othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced1321b5c66225fab8a05a5d80969ad
https://doi.org/10.1093/carcin/21.8.1601
https://doi.org/10.1093/carcin/21.8.1601
Autor:
Kimberly Rozett, David M. Mauro, Barbara B. Taylor, Aruna Koganti, Eric H. Weyand, Bing-Li Ma, Deborah A. Spina
Publikováno v:
Environmental Science & Technology. 32:3104-3112
The systemic bioavailability of polynuclear aromatic hydrocarbons (PAH) from ingested soils containing manufactured gas plant (MGP) tar was evaluated in mice. Soil and organic extract of each soil were incorporated into a diet and fed to mice for two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5ce339c5e8f5e7f76fc1bed44b2ccbf
https://doi.org/10.1021/es980082f
https://doi.org/10.1021/es980082f
Autor:
Erik A. Carlson, Thomas R. Sutter, Shirlean Goodwin, Aruna Koganti, Colin Craig McCulloch, Jay B. Silkworth
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 112(1)
Toxicogenomics has great potential for enhancing our understanding of environmental chemical toxicity, hopefully leading to better informed human health risk assessments. This study employed toxicogenomic technology to reveal species differences in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffce5db9359507872f9eccb82ee533f0
https://pubmed.ncbi.nlm.nih.gov/19692669
https://pubmed.ncbi.nlm.nih.gov/19692669
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 36(4)
On the basis of the ability of capsaicin to activate the transient receptor potential vanilloid 1 receptor (TRPV1) expressed in nociceptive sensory neurons, topical and injectable high-concentration formulations are being developed as potential treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21c3f14a9e0958b35c9f046f4563d79
https://pubmed.ncbi.nlm.nih.gov/18180272
https://pubmed.ncbi.nlm.nih.gov/18180272
Autor:
Suzie Chen, Pamela M. Pollock, Jeffrey J. Martino, Raman Sood, Karen J. Dunn, Kerine R. Mackason, James S. Goydos, Christiane M. Robbins, Kevin Ryan, William J. Pavan, Michael Eckhaus, Steven M. Crespo-Carbone, Christopher L. Graham, Yarí E. Marín, Jun Cheng, Daniel Sinsimer, Jin Namkoong, Arturo Incao, Kenneth R. Reuhl, Jeffrey M. Trent, Izabela Makalowska, Amy Chen, Kathleen G. Roberts, Laura M. Yudt, Aruna Koganti, Heather W. Pinkett, Paul S. Meltzer, Seung Shick Shin, Hua Zhu, Karine A. Cohen-Solal
Publikováno v:
Nature genetics. 34(1)
To gain insight into melanoma pathogenesis, we characterized an insertional mouse mutant, TG3, that is predisposed to develop multiple melanomas. Physical mapping identified multiple tandem insertions of the transgene into intron 3 of Grm1 (encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f92780953cdce9df58bcdf807a24c69
https://pubmed.ncbi.nlm.nih.gov/12704387
https://pubmed.ncbi.nlm.nih.gov/12704387
Publikováno v:
Environmental sciencetechnology. 35(13)
7H-Benzo[c]fluorene (benzo[c]fluorene) is a major DNA adduct forming component of coal tar in lung of mice. The present study evaluated the types of PAH:DNA adducts formed from different neat coal tar samples and soils contaminated with coal tar. Mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d265719ee4065e74c1e9e27d47bff7db
https://pubmed.ncbi.nlm.nih.gov/11452595
https://pubmed.ncbi.nlm.nih.gov/11452595
Autor:
Eric H. Weyand, Lewis V. Rodriguez, Yung-Cheng Chen, Yun Wu, Harold A. Dunsford, Aruna Koganti
Publikováno v:
Chemical research in toxicology. 8(7)
The tumorigenic activity of manufactured gas plant residue (MGP) was evaluated in female A/J mice using a F0927 basal gel diet system. Adulterated diets containing MGP (0.10% or 0.25%) or benzo[a]pyrene (B[alpha]P; 16 or 98 ppm) were fed for 260 days
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70775f4660c5038c1a9827ce093230ac
https://pubmed.ncbi.nlm.nih.gov/8555410
https://pubmed.ncbi.nlm.nih.gov/8555410