Výsledky vyhledávání - "Aruna Barade"

Impact of donor telomere length on survival in patients undergoing matched sibling donor transplantation for aplastic anaemia

Autor: Eunice Sindhuvi Edison, Aruna Barade, Fouzia N. Aboobacker, Kavitha M Lakshmi, Anup J. Devasia, Aby Abraham, Anu Korula, Biju George, Vikram Mathews

Publikováno v: British journal of haematologyReferences. 196(3)

Although telomere shortening is seen frequently in patients with aplastic anaemia (AA), there are no data on its association in matched sibling donor (MSD) transplants. We evaluated the effect of pre-transplant telomere length of patients and donors,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f62943bdf5e6a8f90176c0a6e484f2
https://pubmed.ncbi.nlm.nih.gov/34605011

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Germline Variants Contribute Significantly to the Pathogenesis of Aplastic Anemia in India

Autor: Aruna Barade, Kavitha M Lakshmi, Biju George, Anu Korula, Arun Kumar Arunachalam, Aby Abraham, Deborah Arul, Vikram Mathews, Anup J. Devasia, Eunice Sindhuvi Edison, Fouzia Na

Publikováno v: Blood. 138:1105-1105

Introduction Aplastic anemia (AA) is characterized by a hypoplastic marrow and bone marrow failure (BMF), leading to peripheral pancytopenia. The treatment for AA currently consists of either hematopoietic stem cell transplant (HSCT) or immunosuppres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4920431f249fca1727dbfebf1ea1c31b
https://doi.org/10.1182/blood-2021-148348

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Dysregulated Neutrophil Iron Homeostasis in β-Thalassemia Impairs Phagocytosis and Reactive Oxygen Species Production

Autor: Sreenithi Santhakumar, Uday Kulkarni, Aruna Barade, Leo stephen.R, Biju George, Eunice Sindhuvi, Devi V.J

Publikováno v: Blood. 138:942-942

Introduction Beta thalassemia is an inherited disorder characterised by ineffective erythropoiesis leading to anemia and secondary iron overload. Neutrophils are the first line of innate immune defence against infection is dysfunctional in thalassemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b32e9e67c605208e894204a4d30df9b
https://doi.org/10.1182/blood-2021-154482

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Donor Telomere Length Influences Engraftment and Outcome in Aplastic Anemia Patients Undergoing Matched Related Stem Cell Transplantation

Autor: Aruna Barade, Aby Abraham, Biju George, Vikram Mathews, Eunice Sindhuvi, Nisham Pn, Kavitha M Lakshmi, Anu Korula, Alok Srivastava, Anup J. Devasia, Uday Kulkarni

Publikováno v: Biology of Blood and Marrow Transplantation. 24:S294-S295

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6cfea7f7aa4e2345459093ad8a80a66
https://doi.org/10.1016/j.bbmt.2017.12.335

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Decreased Iron Utilization Leads to Dysregulation of Iron Homeostasis in Aplastic Anemia

Autor: Eunice Sindhuvi Edison, Aruna Barade, Biju George, Sreenithi Santhakumar

Publikováno v: Blood. 132:3872-3872

Aplastic Anemia (AA) arises due to specific failure of bone marrow precursor cells or stem cells to produce adequate amount of mature hematopoietic cells. Erythropoiesis utilizes majority of iron in humans. Erythropoietic activity is fine-tuned with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee7c9cf7405e2e74b789a347885215e7
https://doi.org/10.1182/blood-2018-99-118010

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