Elucidating osseointegration in vivo in 3D printed scaffolds eliciting different foreign body responses

Autor: Dewei Qiu, Chuanliang Cao, Aruna Prasopthum, Zhenchang Sun, Shan Zhang, Hanwen Yang, Zhiyong Xu, Jun Tao, Fanrong Ai, Jing Yang

Publikováno v: Materials Today Bio, Vol 22, Iss , Pp 100771- (2023)

Osseointegration between biomaterial and bone is critical for the clinical success of many orthopaedic and dental implants. However, the mechanisms of in vivo interfacial bonding formation and the role of immune cells in this process remain unclear.

Externí odkaz: https://doaj.org/article/ecbc9e26f1624f60b413a9bd9ebc57f7

Characterisation of bone regeneration in 3D printed ductile PCL/PEG/hydroxyapatite scaffolds with high ceramic microparticle concentrations

Autor: Aruna Prasopthum, Andrew J. Parsons, Chuanliang Cao, Fanrong Ai, Jing Yang, Pengren Huang

Publikováno v: Biomaterials Science. 10:138-152

3D printed bioactive glass or bioceramic particle reinforced composite scaffolds for bone tissue engineering currently suffer from low particle concentration (100% breaking strain) by adding poly(ethylene glycol) which is biocompatible and FDA approv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccaae512ff785165ce6e3837d0e4a627
https://doi.org/10.1039/d1bm01645h

Structure–activity relationship and in vitro inhibition of human cytochrome CYP2A6 and CYP2A13 by flavonoids

Autor: Khanistha Prakobsri, Aruna Prasopthum, Phisit Pouyfung, Supattra Boonruang, Songklod Sarapusit, Pornpimol Rongnoparut

Publikováno v: Xenobiotica. 50:630-639

Cigarette smoking is one of the major risk factors of various diseases including respiratory diseases and lung cancer. While the liver-specific CYP2A6 is associated with the nicotine clearance and ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed73a7e3afd5ab685d2bad2544725e2c
https://doi.org/10.1080/00498254.2019.1675101

Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea

Autor: Phisit Pouyfung, Khanistha Prakobsri, Supattra Boonruang, Ekaruth Srisook, Aruna Prasopthum, Songklod Sarapusit, Pornpimol Rongnoparut

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1136-1142 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry

The human liver cytochrome P450 (CYP) 2A6 and the respiratory CYP2A13 enzymes play role in nicotine metabolism and activation of tobacco-specific nitrosamine carcinogens. Inhibition of both enzymes could offer a strategy for smoking abstinence and de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb30893fd6f67dc691ceefa0234c053
https://doaj.org/article/75f09d2a437d4acba2d87cedfbba1e00

Three-Dimensional Printed Scaffolds with Controlled Micro-/Nanoporous Surface Topography Direct Chondrogenic and Osteogenic Differentiation of Mesenchymal Stem Cells

Autor: Kevin M. Shakesheff, Mick Cooper, Jing Yang, Aruna Prasopthum

Publikováno v: ACS applied materialsinterfaces. 11(21)

The effect of topography in three-dimensional (3D) printed polymer scaffolds on stem cell differentiation is a significantly underexplored area. Compared to two-dimensional (2D) biomaterials on which various well-defined topographies have been incorp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997cc07de09bfffa9671b3fee6b16228
https://pubmed.ncbi.nlm.nih.gov/31067023