A Review of Vaccine Approaches for West Nile Virus

Autor: Konstantin G. Kousoulas, Arun V. Iyer

Publikováno v: International Journal of Environmental Research and Public Health, Vol 10, Iss 9, Pp 4200-4223 (2013)
International Journal of Environmental Research and Public Health

The West Nile virus (WNC) first appeared in North America in 1999. The North American lineages of WNV were characterized by the presence of neuroinvasive and neurovirulent strains causing disease and death in humans, birds and horses. The 2012 WNV se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f58c829366b37be236bd88418c330c
http://www.mdpi.com/1660-4601/10/9/4200

The Herpes Simplex Virus Type 1 UL20 Protein and the Amino Terminus of Glycoprotein K (gK) Physically Interact with gB

Autor: Joohyun Kim, Sona Chowdhury, Vladimir N. Chouljenko, Konstantin G. Kousoulas, Arun V. Iyer

Publikováno v: Journal of Virology. 84:8596-8606

Herpes simplex virus type 1 (HSV-1) glycoprotein K (gK) and the UL20 protein (UL20p) are strictly required for virus-induced cell fusion, and mutations within either the gK or UL20 gene cause extensive cell fusion (syncytium formation). We have shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1115db7ba3c33b34c2cb26c1f54d9579
https://doi.org/10.1128/jvi.00298-10

Recombinant vesicular stomatitis virus-based west Nile vaccine elicits strong humoral and cellular immune responses and protects mice against lethal challenge with the virulent west Nile virus strain LSU-AR01

Autor: Vladimir N. Chouljenko, Preston A. Marx, Cristian Apetrei, Alma Roy, Arun V. Iyer, Nobuko Wakamatsu, Abolghasem Baghian, Marc J. Boudreaux, Bapi Pahar, Konstantin G. Kousoulas

Publikováno v: Vaccine

Vesicular stomatitis virus (VSV) has been extensively utilized as a viral vector system for the induction of protective immune responses against a variety of pathogens. We constructed recombinant VSVs specifying either the Indiana or Chandipura virus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d053e698292fc7d49bae6e84a395794
https://doi.org/10.1016/j.vaccine.2008.11.087

Clostridium taeniosporum is a close relative of the Clostridium botulinum Group II

Autor: Arun V. Iyer, Mark J. Jacobson, Mary Lou Harrison, Alexandra Blinkova, Eric A. Johnson, James R. Walker, William H. Tepp, Shing-Yi Yang, George N. Bennett

Publikováno v: Anaerobe. 14:318-324

Clostridium taeniosporum is a Gram-positive, anaerobic, rod-shaped non-toxigenic organism isolated from Crimean lake silt. It is unique in forming spores from which about twelve large, flat, ribbon-like appendages emanate. These ribbon-like structure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0e6b7fa5b0d2a9c2e11ba3b6319cca
https://doi.org/10.1016/j.anaerobe.2008.11.004

Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A (H1N1) virus infection

Autor: Arun V. Iyer, Mona H. Haron, Dan Edwall, Nirmal Pugh, K. Gus Kousoulas, David S. Pasco, Lars Lindmark

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 22(2)

A growing body of research indicates that oral administration of bacteria (such as probiotics) can exhibit a protective effect against influenza A (H1N1) viral infection in mice. In the present study, we used a mouse model to examine whether oral adm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6cccb755d4d3707bcaa7c2d64599b8d
https://pubmed.ncbi.nlm.nih.gov/25765832