Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Arun P. Pandurangan"'
Autor:
Matthew D. Johnson, Doulin C. Shepherd, Hiroyuki D. Sakai, Manasi Mudaliyar, Arun Prasad Pandurangan, Francesca L. Short, Paul D. Veith, Nichollas E. Scott, Norio Kurosawa, Debnath Ghosal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract DPANN is a widespread and diverse group of archaea characterized by their small size, reduced genome, limited metabolic pathways, and symbiotic existence. Known DPANN species are predominantly obligate ectosymbionts that depend on their host
Externí odkaz:
https://doaj.org/article/baf22a05adb34b09af0e6eaa62c2a712
Autor:
Christopher Ruis, Aaron Weimann, Gerry Tonkin-Hill, Arun Prasad Pandurangan, Marta Matuszewska, Gemma G. R. Murray, Roger C. Lévesque, Tom L. Blundell, R. Andres Floto, Julian Parkhill
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract As observed in cancers, individual mutagens and defects in DNA repair create distinctive mutational signatures that combine to form context-specific spectra within cells. We reasoned that similar processes must occur in bacterial lineages, p
Externí odkaz:
https://doaj.org/article/cc2a1f59c84346ceb130c517a1c473fa
Autor:
Chang Lu, Jan Zaucha, Rihab Gam, Hai Fang, Ben Smithers, Matt E. Oates, Miguel Bernabe-Rubio, James Williams, Natalie Zelenka, Arun Prasad Pandurangan, Himani Tandon, Hashem Shihab, Raju Kalaivani, Minkyung Sung, Adam J. Sardar, Bastian Greshake Tzovoras, Davide Danovi, Julian Gough
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Systematically predicting phenotypes or disease risks based on the information of an individual’s genetic variation remains an unsolved challenge. Here, the authors develop a knowledge-based approach for performing and evaluating hypothesis-free ph
Externí odkaz:
https://doaj.org/article/fe21f256cb6b4004bd97bf5b493f46e6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1874-1884 (2023)
Multi-drug resistant tuberculosis is categorised by the World Health Organisation (WHO) as a public health crisis. In silico techniques were used to probe the structural basis of Mycobacterium tuberculosis resistance to isoniazid and streptomycin. Is
Externí odkaz:
https://doaj.org/article/99937c29fff44dff802cd6af4f0c0608
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/2d2738565626488083509b2aadba85bb
Autor:
Christopher A. Beaudoin, Emmanouela Petsolari, Samir W. Hamaia, Sharif Hala, Fadwa S. Alofi, Arun P. Pandurangan, Tom L. Blundell, Sundeep Chaitanya Vedithi, Christopher L.-H. Huang, Antony P. Jackson
Publikováno v:
Biochemical and Biophysical Research Communications. 666:61-67
The RGD motif on the SARS-CoV-2 spike protein has been suggested to interact with RGD-binding integrins αVβ3 and α5β1 to enhance viral cell entry and alter downstream signaling cascades. The D405N mutation on the Omicron subvariant spike proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33106946ebb34dbf0d56168230eb7b09
https://doi.org/10.1016/j.bbrc.2023.04.088
https://doi.org/10.1016/j.bbrc.2023.04.088
Autor:
Typhaine Paysan-Lafosse, Matthias Blum, Sara Chuguransky, Tiago Grego, Beatriz Lázaro Pinto, Gustavo A Salazar, Maxwell L Bileschi, Peer Bork, Alan Bridge, Lucy Colwell, Julian Gough, Daniel H Haft, Ivica Letunić, Aron Marchler-Bauer, Huaiyu Mi, Darren A Natale, Christine A Orengo, Arun P Pandurangan, Catherine Rivoire, Christian J A Sigrist, Ian Sillitoe, Narmada Thanki, Paul D Thomas, Silvio C E Tosatto, Cathy H Wu, Alex Bateman
Publikováno v:
Nucleic Acids Research. 51:D418-D427
The InterPro database (https://www.ebi.ac.uk/interpro/) provides an integrative classification of protein sequences into families, and identifies functionally important domains and conserved sites. Here, we report recent developments with InterPro (v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153bbcbf1ab56d7f060b0d1aec9c1f19
https://doi.org/10.1093/nar/gkac993
https://doi.org/10.1093/nar/gkac993
Publikováno v:
Cells, Vol 8, Iss 10, p 1189 (2019)
The process of direct cell reprogramming, also named transdifferentiation, permits for the conversion of one mature cell type directly into another, without returning to a dedifferentiated state. This makes direct reprogramming a promising approach f
Externí odkaz:
https://doaj.org/article/a603ec5c6489454aafb3fe95f4ab6aaf
Autor:
Christopher A. Beaudoin, Arun P. Pandurangan, So Yeon Kim, Samir W. Hamaia, Christopher L.‐H. Huang, Tom L. Blundell, Sundeep Chaitanya Vedithi, Antony P. Jackson
Publikováno v:
Journal of medical virology. 94(9)
Funder: American Leprosy Missions; Id: http://dx.doi.org/10.13039/100016315
Funder: Antibiotic Research UK; Id: http://dx.doi.org/10.13039/100011694
Funder: Wellcome Trust
Cleavage of the severe respiratory syndrome coronavirus-2 (SARS
Funder: Antibiotic Research UK; Id: http://dx.doi.org/10.13039/100011694
Funder: Wellcome Trust
Cleavage of the severe respiratory syndrome coronavirus-2 (SARS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec9b1b0de21db24912d56c70e567b75
https://pubmed.ncbi.nlm.nih.gov/35575289
https://pubmed.ncbi.nlm.nih.gov/35575289
Autor:
Carl Leung, Natalya V Dudkina, Natalya Lukoyanova, Adrian W Hodel, Irene Farabella, Arun P Pandurangan, Nasrin Jahan, Mafalda Pires Damaso, Dino Osmanović, Cyril F Reboul, Michelle A Dunstone, Peter W Andrew, Rana Lonnen, Maya Topf, Helen R Saibil, Bart W Hoogenboom
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/3ccb4083d8e948e290b3b3a5965a0e9c