Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Arun Mouli, Kolinjivadi"'
Autor:
Arun Mouli Kolinjivadi, Siao Ting Chong, Ramveer Choudhary, Haresh Sankar, Ee Ling Chew, Claresta Yeo, Sock Hoai Chan, Joanne Ngeow
Publikováno v:
Human Molecular Genetics. 32:1401-1409
Monoallelic or biallelic RAD51C germline mutations results in chromosome instability disorders such as fanconi anemia (FA) and cancers. The bona fide function of RAD51C is to assist RAD51 nucleoprotein filament onto single strand DNA to complete Homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9839c4262591a414bccfdee6e7bd58de
https://doi.org/10.1093/hmg/ddac281
https://doi.org/10.1093/hmg/ddac281
Autor:
Lavina Sierra Tay, Vaidehi Krishnan, Haresh Sankar, Yu Lin Chong, Linda Shyue Huey Chuang, Tuan Zea Tan, Arun Mouli Kolinjivadi, Dennis Kappei, Yoshiaki Ito
Publikováno v:
Cell Reports, Vol 24, Iss 7, Pp 1747-1755 (2018)
Summary: The Fanconi anemia (FA) pathway is a pivotal genome maintenance network that orchestrates the repair of DNA interstrand crosslinks (ICLs). The tumor suppressors RUNX1 and RUNX3 were shown to regulate the FA pathway independent of their canon
Externí odkaz:
https://doaj.org/article/b9a6916abb5a4fa58b6f939ea3d9f411
Publikováno v:
Human Molecular Genetics. 29:R158-R164
Germline mutations in Fanconi anemia (FA) genes predispose to chromosome instability syndromes, such as FA and cancers. FA gene products have traditionally been studied for their role in interstrand cross link (ICL) repair. A fraction of FA gene prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abb796f061cb9eace5c7d795ac63285
https://doi.org/10.1093/hmg/ddaa087
https://doi.org/10.1093/hmg/ddaa087
Autor:
Longjie Li, Arun Mouli Kolinjivadi, Kok Haur Ong, David M Young, Gabriel Pik Liang Marini, Sock Hoai Chan, Siao Ting Chong, Ee Ling Chew, Haoda Lu, Laurent Gole, Weimiao Yu, Joanne Ngeow
Motivation DNA fibre assay has a potential application in genomic medicine, cancer and stem cell research at the single-molecule level. A major challenge for the clinical and research implementation of DNA fibre assays is the slow speed in which manu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97942eadae10fcde42e271141a58020e
https://hdl.handle.net/10356/164980
https://hdl.handle.net/10356/164980
Autor:
Arun Mouli, Kolinjivadi, Haresh, Sankar, Ramveer, Choudhary, Lavina Sierra, Tay, Tuan Zea, Tan, Naoko, Murata-Kamiya, Dominic Chih-Cheng, Voon, Dennis, Kappei, Masanori, Hatakeyama, Vaidehi, Krishnan, Yoshiaki, Ito
Publikováno v:
International journal of molecular sciences. 23(3)
The proteins from the Fanconi Anemia (FA) pathway of DNA repair maintain DNA replication fork integrity by preventing the unscheduled degradation of nascent DNA at regions of stalled replication forks. Here, we ask if the bacterial pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66ca1e9ada10525036ceb7a12616092d
https://pubmed.ncbi.nlm.nih.gov/35163588
https://pubmed.ncbi.nlm.nih.gov/35163588
Publikováno v:
Journal of Molecular Cell Biology
RUNX genes belong to a three-membered family of transcription factors, which are well established as master regulators of development. Of them, aberrations in RUNX3 expression are frequently observed in human malignancies primarily due to epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38446087c9712dfc3fd3f4e07dc4b79b
https://doi.org/10.1093/jmcb/mjy076
https://doi.org/10.1093/jmcb/mjy076
Publikováno v:
Endocrine-related cancer. 28(2)
Co-ordinated oscillation of mammalian circadian clock and cell cycle is essential for cellular and organismal homeostasis. Existing preclinical, epidemiological, molecular and biochemical evidence reveals a robust interplay between circadian clock, g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170b2be0350aea7775db104de97d4d75
https://pubmed.ncbi.nlm.nih.gov/33300498
https://pubmed.ncbi.nlm.nih.gov/33300498
Multiple neoplasia in a patient with Gitelman syndrome harboring germline monoallelic MUTYH mutation
Autor:
Li Shao-Tzu, Joanne Ngeow, Sock Hoai Chan, Arnoud Boot, Min-Hoe Chew, Nur Diana Binte Ishak, Ming Ren Toh, Jason Yongsheng Chan, Arun Mouli Kolinjivadi, Siao Ting Chong, Elizabeth Lee
Publikováno v:
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-6 (2020)
Gitelman syndrome is a rare, recessively inherited disease characterized by chronic hypokalemia and hypomagnesemia as a result of defective electrolyte co-transport at the level of the distal convoluted tubule of the kidney. Here, we present the firs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841399aacef04945016eacc5ade5dbe6
https://doi.org/10.1038/s41525-020-00146-9
https://doi.org/10.1038/s41525-020-00146-9
Autor:
Soo-Chin Lee, Weng Khong Lim, Zoe Li Ting Ang, Arun Mouli Kolinjivadi, Diana Ishak, Jianbang Chiang, Sock Hoai Chan, Haresh Sankar, Tarryn Shaw, Jing Xian Teo, Eliza Courtney, Siao Ting Chong, Marie Loh, Hui-Yuan Yeh, Joanne Ngeow, Li Zhou, Shao-Tzu Li
Publikováno v:
International journal of cancerREFERENCES. 148(3)
Identification of ancestry-specific pathogenic variants is imperative for diagnostic, treatment, management and prevention strategies, and to understand penetrance/modifiers on risk. Our study aimed to determine the clinical significance of a recurre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3be04dd1005459d29088af2f0be4a9
https://pubmed.ncbi.nlm.nih.gov/32745242
https://pubmed.ncbi.nlm.nih.gov/32745242
Autor:
Jason Yongsheng, Chan, Ming Ren, Toh, Siao Ting, Chong, Nur Diana Binte, Ishak, Arun Mouli, Kolinjivadi, Sock Hoai, Chan, Elizabeth, Lee, Arnoud, Boot, Li, Shao-Tzu, Min-Hoe, Chew, Joanne, Ngeow
Publikováno v:
NPJ Genomic Medicine
Gitelman syndrome is a rare, recessively inherited disease characterized by chronic hypokalemia and hypomagnesemia as a result of defective electrolyte co-transport at the level of the distal convoluted tubule of the kidney. Here, we present the firs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c72f5d6a799e8e14c91428bbba15700
https://pubmed.ncbi.nlm.nih.gov/33024574
https://pubmed.ncbi.nlm.nih.gov/33024574