Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Arun Kumar, Selvam"'
Autor:
Carlos Fernández Moro, Arun Kumar Selvam, Mehran Ghaderi, Ville N. Pimenoff, Marco Gerling, Béla Bozóky, Soledad Pouso Elduayen, Joakim Dillner, Mikael Björnstedt
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. PDAC has a dismal prognosis and an inherent resistance to cytostatic drugs. The lack of reliable experimental models is a severe limitation for drug development tar
Externí odkaz:
https://doaj.org/article/eb1992e46a424f3fbb7f5de9bc7d35fa
Autor:
Tímea Szekerczés, Arun Kumar Selvam, Carlos Fernández Moro, Soledad Pouso Elduayen, Joakim Dillner, Mikael Björnstedt, Mehran Ghaderi
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 167 (2023)
Patient-derived tissue culture models are valuable tools to investigate drug effects and targeted treatment approaches. Resected tumor slices cultured ex vivo have recently gained interest in precision medicine, since they reflect the complex microen
Externí odkaz:
https://doaj.org/article/c7ee6b00f8b6433d815adca6369bc29f
Autor:
Arun Kumar Selvam, Rim Jawad, Roberto Gramignoli, Adnane Achour, Hugh Salter, Mikael Björnstedt
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1094 (2021)
Despite progress in the treatment of non-visceral malignancies, the prognosis remains poor for malignancies of visceral organs and novel therapeutic approaches are urgently required. We evaluated a novel therapeutic regimen based on treatment with Se
Externí odkaz:
https://doaj.org/article/c8314138eecb46ac99b5607e3993ddf1
Autor:
Arun Kumar Selvam, Mikael Björnstedt
Publikováno v:
Antioxidants, Vol 9, Iss 2, p 139 (2020)
Kynurenine aminotransferase 1 (KYAT1 or CCBL1) plays a major role in Se-methylselenocysteine (MSC) metabolism. It is a bi-functional enzyme that catalyzes transamination and beta-elimination activity with a single substrate. KYAT1 produces methylsele
Externí odkaz:
https://doaj.org/article/3b5d6a1f98e64649a0fb8b89b7fe1cb6
Autor:
Tímea Szekerczés, Gábor Lendvai, Zsuzsa Schaff, Arun Kumar Selvam, Mikael Björnstedt, Endre Kontsek, Attila Szakos, András Kiss
Publikováno v:
Pathology Oncology Research
The unique character of selenium compounds, including sodium selenite and Se-methylselenocysteine (MSC), is that they exert cytotoxic effects on neoplastic cells, providing a great potential for treating cancer cells being highly resistant to cytosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85170488eac7380c3c6fb5e158f9d35
http://europepmc.org/articles/PMC7471166
http://europepmc.org/articles/PMC7471166
Publikováno v:
Methods in enzymology. 662
Selenium compounds have pronounced effects on cell growth and proliferation. Nutritional levels induce selenoproteins. However, the antineoplastic effects of supra-nutritional selenium levels are not mediated by selenoproteins. The most studied compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fd090008a5bfa3bacf4528fcf8da24c
https://pubmed.ncbi.nlm.nih.gov/35101213
https://pubmed.ncbi.nlm.nih.gov/35101213
Publikováno v:
Methods in Enzymology ISBN: 9780323907354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de64c5ef6bc141e5e0e49a57e25f0723
https://doi.org/10.1016/bs.mie.2021.10.019
https://doi.org/10.1016/bs.mie.2021.10.019
Autor:
Rim Jawad, Adnane Achour, Roberto Gramignoli, Arun Kumar Selvam, Hugh Salter, Mikael Björnstedt
Publikováno v:
Antioxidants
Volume 10
Issue 7
Antioxidants, Vol 10, Iss 1094, p 1094 (2021)
Volume 10
Issue 7
Antioxidants, Vol 10, Iss 1094, p 1094 (2021)
Despite progress in the treatment of non-visceral malignancies, the prognosis remains poor for malignancies of visceral organs and novel therapeutic approaches are urgently required. We evaluated a novel therapeutic regimen based on treatment with Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d35461c6997d209927d34f479155ce
Autor:
Sougat Misra, Aditya Ambati, András Matolcsy, Arun Kumar Selvam, Isabelle Magalhaes, Marita Wallenberg, Mikael Björnstedt, Gilbert Lauter
Publikováno v:
Oncotarget
// Sougat Misra 1 , Arun Kumar Selvam 1 , Marita Wallenberg 1 , Aditya Ambati 2,3 , Andras Matolcsy 4 , Isabelle Magalhaes 5 , Gilbert Lauter 6 and Mikael Bjornstedt 1 1 Department of Laboratory Medicine, Division of Pathology F46, Karolinska Institu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b698bab9fbd3fb59857f15b29cc3f7c8
http://europepmc.org/articles/PMC5342695
http://europepmc.org/articles/PMC5342695
Publikováno v:
Molecular and Integrative Toxicology ISBN: 9783319953892
The potential applications of different selenium compounds as cancer chemotherapeutic agents is an active area of research within the field of cancer drug discovery. The antineoplastic efficacies of many of these small molecules have been extensively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9083509b9ac0276592c5fd9569acec
https://doi.org/10.1007/978-3-319-95390-8_13
https://doi.org/10.1007/978-3-319-95390-8_13