Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Arun K Nalla"'
Autor:
Emily A Bruce, Meei-Li Huang, Garrett A Perchetti, Scott Tighe, Pheobe Laaguiby, Jessica J Hoffman, Diana L Gerrard, Arun K Nalla, Yulun Wei, Alexander L Greninger, Sean A Diehl, David J Shirley, Debra G B Leonard, Christopher D Huston, Beth D Kirkpatrick, Julie A Dragon, Jessica W Crothers, Keith R Jerome, Jason W Botten
Publikováno v:
PLoS Biology, Vol 18, Iss 10, p e3000896 (2020)
The ongoing COVID-19 pandemic has created an unprecedented need for rapid diagnostic testing. The World Health Organization (WHO) recommends a standard assay that includes an RNA extraction step from a nasopharyngeal (NP) swab followed by reverse tra
Externí odkaz:
https://doaj.org/article/54f6f0859c2e48d5a294bcb9407b675d
Autor:
Samuel S. Minot, Vikas Peddu, Alexander L. Greninger, Keith R. Jerome, Arun K. Nalla, Meei Li Huang, Lasata Shrestha, Pavitra Roychoudhury, Hong Xie, Garrett A. Perchetti, Quynh Phung, Adam Reinhardt, Ryan C. Shean, Shriya B. Reddy
Publikováno v:
Clinical Chemistry
Background More than 2 months separated the initial description of SARS-CoV-2 and discovery of its widespread dissemination in the United States. Despite this lengthy interval, implementation of specific quantitative reverse transcription (qRT)-PCR-b
Autor:
Sarah A. McGuffin, Vidya Atluri, Santiago Neme, Meei-Li Huang, Seth A Cohen, Helen Y. Chu, Frederick S. Buckner, H. Nina Kim, Denise J. McCulloch, Keith R. Jerome, Alexander L. Greninger, Arun K. Nalla, Michela Blain, Margaret L. Green
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases
Clinical Infectious Diseases
BackgroundWashington State served as the initial epicenter of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in the United States. An understanding of the risk factors and clinical outcomes of hospitalized patients with cor
Autor:
Alexander L. Greninger, Richard Kim, Keith R. Jerome, Patricia M Kritek, Bijan J Ghassemieh, Sudhakar Pipavath, Arun K. Nalla, Andrew M Luks, Jason D Goldman, Laura Evans, Pavan K. Bhatraju, Carmen Mikacenic, Michelle Nichols, T. Eoin West, Christopher R. Dale, Mark M Wurfel, D. Shane O’Mahony, Anthony Gerbino
Publikováno v:
New England Journal of Medicine
The New England Journal of Medicine
The New England Journal of Medicine
Background Community transmission of coronavirus 2019 (Covid-19) was detected in the state of Washington in February 2020. Methods We identified patients from nine Seattle-area hospitals who were admitted to the intensive care unit (ICU) with confirm
Autor:
Arun K. Nalla, Grant D. Trobridge
Publikováno v:
Biomedicines, Vol 4, Iss 2, p 8 (2016)
Stem cell gene therapy approaches for Human Immunodeficiency Virus (HIV) infection have been explored in clinical trials and several anti-HIV genes delivered by retroviral vectors were shown to block HIV replication. However, gammaretroviral and lent
Externí odkaz:
https://doaj.org/article/18f8ab41c0714a489719b6e337a5eb11
Publikováno v:
Journal of Clinical Virology
Highlights • Multiplexing three targets in a single-reaction maintains LDT assay performance. • Triplexing correctly identified SARS-CoV-2 in 98.4% positive or inconclusive samples. • Primers and probes used in multiplexed assays are virus spec
Autor:
Jay Shendure, Kirsten Lacombe, Xianding Deng, Suxiang Tong, Richard A. Neher, Scot Federman, Michael Famulare, Jover Lee, Melissa Truong, Caitlin R Wolf, Geoffrey S. Baird, Matthew Richardson, Amanda Adler, Charles Y. Chiu, Scott Lindquist, Thomas R. Sibley, Geoff Melly, Elisabeth Brandstetter, Deborah A. Nickerson, Duncan MacCannell, Anahita Kiavand, Krista Queen, Pavitra Roychoudhury, Janet A. Englund, Gregory Pepper, Wei Gu, Lasata Shrestha, Ying Tao, Emma B. Hodcroft, Trevor Bedford, Danielle Giroux, Nicola F. Müller, Kairsten Fay, Lea M. Starita, Misja Ilcisin, Philip Dykema, Jeffrey S. Duchin, Louise H. Moncla, Alexander L. Greninger, Shari Cho, Hong Xie, James Hadfield, Brian Hiatt, Keith R. Jerome, Peter D Han, Arun K. Nalla, Gregory L. Armstrong, Helen Y. Chu, Anna Uehara, Truong N. Nguyen, Romesh Gautom, John Huddleston, Adam Reinhardt, Meei-Li Huang, Mark J. Rieder, Chris D. Frazar
Publikováno v:
medRxiv
Science
Science (New York, N.y.)
Science
Science (New York, N.y.)
A series of unfortunate events The history of how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread around the planet has been far from clear. Several narratives have been propagated by social media and, in some cases, national poli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f3961b3a4ecca5e0a39aa9b8574e30
Autor:
Alexander L. Greninger, Amanda M. Casto, Arun K. Nalla, Keith R. Jerome, Garrett A. Perchetti, Lasata Shrestha, Haiying Zhu, Meei-Li Huang, Reigran Sampoleo, Yulun Wei
Publikováno v:
medRxiv
Journal of Clinical Microbiology
Journal of Clinical Microbiology
Nearly 400,000 people worldwide are known to have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) beginning in December 2019. The virus has now spread to over 168 countries including the United States, where the first
Autor:
Michael L. Jackson, Arun K. Nalla, Jane Kuypers, Helen Y. Chu, Emily E. Scott, Pavitra Roychoudury
Publikováno v:
The Journal of infectious diseases. 223(1)
BackgroundVaccines and novel prophylactics against respiratory syncytial virus (RSV) are in development. To provide a baseline for evaluating these interventions, we characterized the incidence and molecular epidemiology of RSV in persons aged ≥1 y
Autor:
Eileen J. Klein, Janet A. Englund, Bonnie Strelitz, Garrett A. Perchetti, Alpana Waghmare, Arun K. Nalla, Jane Kuypers, Joana Y Lively, Kirsten Lacombe, Brian Rha, Claire M Midgley
Publikováno v:
Open Forum Infectious Diseases
Background Rhinovirus (RV) quantitation by reverse transcription-quantitative PCR is limited by variable amplification efficiency across genotypes. We used a precise viral quantitation method, reverse transcription-digital PCR (RT-dPCR), to character