Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Arun K Haldar"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86684 (2014)
Cell-autonomous immunity to the bacterial pathogen Chlamydia trachomatis and the protozoan pathogen Toxoplasma gondii is controlled by two families of Interferon (IFN)-inducible GTPases: Immunity Related GTPases (IRGs) and Guanylate binding proteins
Externí odkaz:
https://doaj.org/article/1a759a43accc4ee5a2ed6d9d843cc547
Autor:
Arun K Haldar, Hector A Saka, Anthony S Piro, Joe Dan Dunn, Stanley C Henry, Gregory A Taylor, Eva M Frickel, Raphael H Valdivia, Jörn Coers
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003414 (2013)
Interferon-inducible GTPases of the Immunity Related GTPase (IRG) and Guanylate Binding Protein (GBP) families provide resistance to intracellular pathogenic microbes. IRGs and GBPs stably associate with pathogen-containing vacuoles (PVs) and elicit
Externí odkaz:
https://doaj.org/article/d850e28d862a44b7a4c21959a7baf791
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
mBio
mBio
The obligate intracellular parasite Leishmania causes the disease leishmaniasis, which is transmitted to mammalian hosts, including humans, via the sandfly vector. Following the bite-induced breach of the skin barrier, Leishmania is known to live and
Autor:
Nichole Orench-Rivera, Miriam Kutsch, Gregory A. Taylor, Seungmin Hwang, Ryan Finethy, Anthony S. Piro, Jennifer Martinez, Sarah Luoma, Arun K. Haldar, Jacob Dockterman, Graham D. Wallace, Meta J. Kuehn, Jörn Coers
Publikováno v:
EMBO Rep
Inflammation associated with gram-negative bacterial infections is often instigated by the bacterial cell wall component lipopolysaccharide (LPS). LPS-induced inflammation and resulting life-threatening sepsis are mediated by the two distinct LPS rec
Autor:
Arun K. Haldar, Seungmin Hwang, Jacob Dockterman, Gregory A. Taylor, Ryan Finethy, Anthony S. Piro, Graham D. Wallace, Miriam Kutsch, Meta J. Kuehn, Sarah Luoma, Jennifer Martinez, Nichole Orench-Rivera, Jörn Coers
Inflammation associated with gram-negative bacterial infections is often instigated by the bacterial cell wall component lipopolysaccharide (LPS). LPS-induced inflammation and resulting life-threatening sepsis are mediated by the two distinct LPS rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6bb6465931ca1fedb488a20934f6df
Autor:
Md. Arafat Hussain, Namita Chauhan, Shibnath Mazumder, Arun K. Haldar, Shagun Sharma, Ruchi Bharti, Amit Kumar Sahu, Tanmay Majumdar, Agam P. Singh, Vipin Singh Rana, Inderjeet Kalia, Manmohan Kumar
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 3, Pp 1-19 (2019)
Cell Death and Disease, Vol 10, Iss 3, Pp 1-19 (2019)
Recent studies have documented the diverse role of host immunity in infection by the protozoan parasite, Toxoplasma gondii. However, the contribution of the β-catenin pathway in this process has not been explored. Here, we show that AKT-mediated pho
Autor:
Ryan Finethy, Sarah Luoma, Nichole Orench-Rivera, Eric M. Feeley, Arun K. Haldar, Masahiro Yamamoto, Thirumala-Devi Kanneganti, Meta J. Kuehn, Jorn Coers, David S. Weiss, Eric J. Rubin
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
mBio
mBio, Vol 8, Iss 5, p e01188-17 (2017)
mBio
mBio, Vol 8, Iss 5, p e01188-17 (2017)
The Gram-negative bacterial cell wall component lipopolysaccharide (LPS) is recognized by the noncanonical inflammasome protein caspase-11 in the cytosol of infected host cells and thereby prompts an inflammatory immune response linked to sepsis. Hos
Autor:
Jörn Coers, Danielle M. Pilla, Jon A. Hagar, Ashley K. Mason, Edward A. Miao, Arun K. Haldar, Daniel Degrandi, Robert K. Ernst, Klaus Pfeffer, Masahiro Yamamoto
Publikováno v:
Proceedings of the National Academy of Sciences. 111:6046-6051
IFN receptor signaling induces cell-autonomous immunity to infections with intracellular bacterial pathogens. Here, we demonstrate that IFN-inducible guanylate binding protein (Gbp) proteins stimulate caspase-11-dependent, cell-autonomous immunity in
Autor:
Hannah E. Brown, David E. Nelson, Jörn Coers, Anthony S. Piro, Arun K. Haldar, Ryan Finethy, Eva-Maria Frickel, Scott T. Espenschied, Amanda M. Giebel
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
mBio
mBio, Vol 7, Iss 6, p e01417-16 (2016)
mBio
mBio, Vol 7, Iss 6, p e01417-16 (2016)
The cytokine gamma interferon (IFN-γ) induces cell-autonomous immunity to combat infections with intracellular pathogens, such as the bacterium Chlamydia trachomatis. The present study demonstrates that IFN-γ-primed human cells ubiquitinate and eli
Autor:
Arun K. Haldar, Rupchand Adak, Syamal Roy, Anindita Chakraborty, Sanchita Datta, Surajit Bhattacharjee, Priyanka Chakraborty, Madhumita Manna
Publikováno v:
Experimental Parasitology. 130:39-47
The present study intends to evaluate the role of radio-attenuated leishmania parasites as immunoprophylactic agents for experimental murine visceral leishmaniasis. BALB/c mice were immunized with gamma (γ)-irradiated Leishmania donovani. A second i