Chemokine signaling in cancer-stroma communications

Autor: Joe W. Gray, Arun J. Singh

Publikováno v: J Cell Commun Signal

Cancer is a multi-faceted disease in which spontaneous mutation(s) in a cell leads to the growth and development of a malignant new organ that if left undisturbed will grow in size and lead to eventual death of the organism. During this process, mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f296e257ac73198701525d17fe5ecc83
https://doi.org/10.1007/s12079-021-00621-7

To roll the eyes and snap a bite – function, development and evolution of craniofacial muscles

Autor: Susanne Dietrich, Arun J. Singh, Chrissa Kioussi, Frank Schubert, Oluwatomisin Afoyalan

Publikováno v: Schubert, F R, Singh, A J, Afoyalan, O, Kioussi, C & Dietrich, S 2018, ' To roll the eyes and snap a bite – function, development and evolution of craniofacial muscles ', Seminars in Cell and Developmental Biology . https://doi.org/10.1016/j.semcdb.2017.12.013

Craniofacial muscles, muscles that move the eyes, control facial expression and allow food uptake and speech, have long been regarded as a variation on the general body muscle scheme. However, evidence has accumulated that the function of head muscle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03fe6d281a124766e389172e72d5563
https://doi.org/10.1016/j.semcdb.2017.12.013

FACS-Seq analysis of Pax3-derived cells identifies non-myogenic lineages in the embryonic forelimb

Autor: Stephen A. Ramsey, Theresa M. Filtz, Arun J. Singh, Chrissa Kioussi, Chih-Ning Chang, Hsiao-Yen Ma

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports

Skeletal muscle in the forelimb develops during embryonic and fetal development and perinatally. While much is known regarding the molecules involved in forelimb myogenesis, little is known about the specific mechanisms and interactions. Migrating sk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db51aab61a24b60020787dc7931ea23d
http://link.springer.com/article/10.1038/s41598-018-25998-1

Expanding the Natural Products Heterologous Expression Repertoire in the Model Cyanobacterium

Autor: Patrick, Videau, Kaitlyn N, Wells, Arun J, Singh, Jessie, Eiting, Philip J, Proteau, Benjamin, Philmus

Publikováno v: ACS Synth Biol

Cyanobacteria are prolific producers of natural products and genome mining has shown that many orphan biosynthetic gene clusters can be found in sequenced cyanobacterial genomes. New tools and methodologies are required to investigate these biosynthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5277c2aa4311ecdafbbfea7a614a60e5
https://pubmed.ncbi.nlm.nih.gov/31846576

Phenotypic Screening of Drug Library in Actively Differentiating Mouse Embryonic Stem Cells

Autor: Arun J. Singh, Michael K. Gross, Chih-Ning Chang, Robert R Allen, Bénédicte Billard, Chrissa Kioussi

Publikováno v: SLAS Discovery. 21:399-407

Phenotypic screening enables the discovery of new drug leads with novel targets. ES cells differentiate into different lineages by successively making use of different subsets of the genome's possible macromolecular interactions. If a compound effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c896b23ea3993f4f56eedc4f3702438d
https://doi.org/10.1177/1087057115624093