Zobrazeno 1 - 10 of 93 pro vyhledávání: '"Arun H.S. Kumar"'
1
Molecular Profiling of Neprilysin Expression and its Interactions with SARS-CoV-2 Spike Proteins to Develop Evidence Base Pharmacological Approaches for Therapeutic Intervention
Autor: Arun H.S. Kumar
Publikováno v: Biology, Engineering, Medicine and Science Reports. 7:15-20
Introduction: Neprilysin due to its peptidase activity is involved in several physiological and pathological processes. Recently our group has reported the association of neprilysin with angiotensin-converting enzyme 2 (ACE2) network proteins which f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd30f7f276461cc782f01f013c609f8e
https://doi.org/10.5530/bems.7.2.7
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2
Modelling the Efficacy of Neprilysin from Various Species in Degrading Different Amyloid-β peptides: Potential Application in Development of Therapeutics for Alzheimer’s Disease
Autor: Arun H.S. Kumar
Publikováno v: Biology, Engineering, Medicine and Science Reports. 7:25-28
Recombinant neprilysin due to its degradation potential against Amyloid-β (Aβ) peptides has been looked at as a potential therapeutic candidate for treating Alzheimer’s disease (AD). However the enzymatic activity of neprilysin against different
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7960edc23131ead1c860140cdce2133
https://doi.org/10.5530/bems.7.2.9
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4
Anatomical perspective on the loss of smell and taste sensation in SARS-CoV-2 infection
Autor: Arun H.S. Kumar, David Kilroy
Publikováno v: Anatomy. 14:145-149
The SARS-CoV-2 virus pandemic that originated from the Wuhan region of China continues to cause major disruptions globally. Loss of smell and taste sensation is reported to be an early indicators of SARS-CoV-2 infection. We provide here an anatomical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86740a1a903d8b2037f2a7480e0acf80
https://doi.org/10.2399/ana.20.049
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5
Efficacy of Natural Extract from Ocimum Species against Fungus Gnats Infesting Plant Saplings
Autor: Anya Kumar, Arun H.S. Kumar
Publikováno v: Biology, Engineering, Medicine and Science Reports. 6:19-21
Background: Fungus gnats around household plants besides being annoying can also compromise the growth the plant saplings. Hence effectively repelling them without compromising their ecological purpose is necessary. Materials and Methods: We tested h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59f7ff339bb03c41a927e3d39b86e661
https://doi.org/10.5530/bems.6.2.6
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6
Molecular Docking of Natural Compounds from Tulsi (Ocimum sanctum) and neem (Azadirachta indica) against SARS-CoV-2 Protein Targets
Autor: Arun H.S. Kumar
Publikováno v: Biology, Engineering, Medicine and Science Reports. 6:11-13
Background: Antiviral activity of tulsi and neem extracts are widely reported. Selected natural compounds from tulsi and neem were hence screened for their efficacy against SARS-CoV-2 targets. Materials and Methods: Using molecular docking tools, the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d56e33d0f5cf5c4ca1d18052f1950a6
https://doi.org/10.5530/bems.6.1.4
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7
Efficacy of Natural Compounds from Tinospora cordifolia Against SARS-CoV-2 Protease, Surface Glycoprotein and RNA Polymerase
Autor: Vasanthkumar Sagar, Arun H.S. Kumar
Publikováno v: Biology, Engineering, Medicine and Science Reports. 6:6-8
Background: Antiviral activity of natural compounds from Tinospora cordifolia (Amritaballi) were evaluated for their efficacy against SARS-CoV-2 targets involved in virus attachment and replication. Materials and Methods: The binding efficacy (bindin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d05f3a2bd73f53f929386732dd6d7a
https://doi.org/10.5530/bems.6.1.2
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8
A Pictogram on Pharmacological Management of Corona Viral Infection: What are the Available Options?
Autor: Arun H.S. Kumar
Publikováno v: Biology, Engineering, Medicine and Science Reports. 5:17-19
Corona virus are known to infect the respiratory and enteric system resulting in benign to several pathological outcomes.1,2 The human coronaviruses typically lead to upper respiratory tract infections resulting in the general common cold symptoms. I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa8ff85f33095d0d2662643a83f76972
https://doi.org/10.5530/bems.5.2.6
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9
Acetamido-propanoic Acid Derived Compounds as Protease Inhibitors to Target Coronaviruses
Autor: Arun H.S. Kumar, Vikram Sharma
Publikováno v: Biology, Engineering, Medicine and Science Reports. 5:20-22
Background: Coronavirus infection as evolved into a major pandemic and is currently being treated using established antiviral agents developed for other similar viruses. Considering the frequent mutations rate in this virus, novel drugs will be neces
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dbf8403b33492c49d004aa3a9de6d6
https://doi.org/10.5530/bems.5.2.7
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10
A Retrospective Analysis of the Merit of Iris-pupil Area Ratio as a Predictor of Risk of Myocardial Infarction
Autor: Arun H.S. Kumar, Ifechukwuamaka Chinaka
Publikováno v: Biology, Engineering, Medicine and Science Reports. 5:23-25
Background: We have recently reported the utility of iris-pupil area ratio as a sensitive index of borderline changes in sympathetic activity and the stress associated with it in primates and canines. As minimal increase in sympathetic activity can l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67360a860881af627875dc216ac85ce4
https://doi.org/10.5530/bems.5.2.8
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