Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Arun B. Agrawal"'
Autor:
Michele Richardson, Anna M. Gallegos, Francine E. Wincott, Arun B. Agrawal, Lori E. Andrews, Cynthia Cushman, Tom J. Parry, Victor Mokler, Pamela Pavco, Lara Maloney
Publikováno v:
Nucleic Acids Research. 27:2569-2577
Vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR play important roles in physiological and pathological angiogenesis. Ribozymes that target the VEGF receptor mRNAs were developed and their biological activities in cell cultur
Autor:
Mark A. Reynolds, Tom J. Parry, Susan Grimm, Francine E. Wincott, Jennifer A. Sandberg, Arun B. Agrawal, Karyn Bouhana, Anna M. Gallegos, Pamela Pavco
Publikováno v:
Antisensenucleic acid drug development. 9(3)
Vascular endothelial growth factor (VEGF) is a growth factor that contributes to the angiogenesis of developing tumors. To interfere with the action of VEGF, a nuclease-stabilized ribozyme, ANGIOZYME, has been developed against VEGF receptor subtype