Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Arun, Sreekumar"'
Autor:
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J. H. Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J. Ellis, Andrea B. Apolo, Leomar Y. Ballester, Jianjun Gao, Donna E. Hansel, Yair Lotan, H. Courtney Hodges, Seth P. Lerner, Chad J. Creighton, Arun Sreekumar, W. Jim Zheng, Pavlos Msaouel, Shyam M. Kavuri, Nagireddy Putluri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract SMARCB1 loss has long been observed in many solid tumors. However, there is a need to elucidate targetable pathways driving growth and metastasis in SMARCB1-deficient tumors. Here, we demonstrate that SMARCB1 deficiency, defined as genomic S
Externí odkaz:
https://doaj.org/article/92dacc4a9b18472087b40b7343faadf4
Autor:
Thanh Nguyen, Dhivya Sridaran, Surbhi Chouhan, Cody Weimholt, Audrey Wilson, Jingqin Luo, Tiandao Li, John Koomen, Bin Fang, Nagireddy Putluri, Arun Sreekumar, Felix Y. Feng, Kiran Mahajan, Nupam P. Mahajan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The testicular androgen biosynthesis is well understood, however, how cancer cells gauge dwindling androgen to dexterously initiate its de novo synthesis remained elusive. We uncover dual-phosphorylated form of sterol regulatory element-bind
Externí odkaz:
https://doaj.org/article/6796f1304f8b4aaf971cec547d08d83d
Autor:
Thanh Nguyen, Dhivya Sridaran, Surbhi Chouhan, Cody Weimholt, Audrey Wilson, Jingqin Luo, Tiandao Li, John Koomen, Bin Fang, Nagireddy Putluri, Arun Sreekumar, Felix Y. Feng, Kiran Mahajan, Nupam P. Mahajan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/bd78901281fb43119a54924b66bf7d3f
Autor:
Anindita Ravindran, Kimiko L. Krieger, Akash K. Kaushik, Hélène Hovington, Sadia Mehdi, Danthasinghe Waduge Badrajee Piyarathna, Vasanta Putluri, Paul Basil, Uttam Rasaily, Franklin Gu, Truong Dang, Jong Min Choi, Rajni Sonavane, Sung Yun Jung, Lisha Wang, Rohit Mehra, Nancy L. Weigel, Nagireddy Putluri, David R. Rowley, Ganesh S. Palapattu, Chantal Guillemette, Louis Lacombe, Éric Lévesque, Arun Sreekumar
Publikováno v:
Cells, Vol 11, Iss 15, p 2329 (2022)
Prostate cancer (PCa) is the second most diagnosed cancer in the United States and is associated with metabolic reprogramming and significant disparities in clinical outcomes among African American (AA) men. While the cause is likely multi-factorial,
Externí odkaz:
https://doaj.org/article/21fa31e76e474fb6b719fbe7d3615cfd
Autor:
Saroj Chakraborty, Anju Lulla, Xi Cheng, Ji-Youn Yeo, Juthika Mandal, Tao Yang, Xue Mei, Piu Saha, Rachel M. Golonka, Beng San Yeoh, Blair Mell, Wei Jia, Vasanta Putluri, Danthasinghe Waduge Badrajee Piyarathna, Nagireddy Putluri, Arun Sreekumar, Katie Meyer, Matam Vijay-Kumar, Bina Joe
Publikováno v:
Journal of Hypertension. 41:979-994
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4e0b2c37b52d2e6a3e3248f84c9349f
https://doi.org/10.1097/hjh.0000000000003423
https://doi.org/10.1097/hjh.0000000000003423
Autor:
Leomar Y. Ballester, Guangrong Lu, Soheil Zorofchian, Venkatrao Vantaku, Vasanta Putluri, Yuanqing Yan, Octavio Arevalo, Ping Zhu, Roy F. Riascos, Arun Sreekumar, Yoshua Esquenazi, Nagireddy Putluri, Jay-Jiguang Zhu
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Cancer cells have altered cellular metabolism. Mutations in genes associated with key metabolic pathways (e.g., isocitrate dehydrogenase 1 and 2, IDH1/IDH2) are important drivers of cancer, including central nervous system (CNS) tumors. Ther
Externí odkaz:
https://doaj.org/article/a7f65a52f3034732b1f065a3ab16d1ce
Autor:
Andreas Martin Lisewski, Joel Patrick Quiros, Monica Mittal, Nagireddy Putluri, Arun Sreekumar, Jesper Z. Haeggström, Olivier Lichtarge
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 1, Pp 31-35 (2018)
In the human malaria parasite Plasmodium falciparum, membrane glutathione S-transferases (GST) have recently emerged as potential cellular detoxifying units and as drug target candidates with the artemisinin (ART) class of antimalarials inhibiting th
Externí odkaz:
https://doaj.org/article/b124a2fd467747e8b370b06737993dba
Autor:
Chen Dai, Jennifer Arceo, James Arnold, Arun Sreekumar, Norman J. Dovichi, Jun Li, Laurie E. Littlepage
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract Background The complex yet interrelated connections between cancer metabolism and oncogenic driver genes are relatively unexplored but have the potential to identify novel biomarkers and drug targets with prognostic and therapeutic value. Th
Externí odkaz:
https://doaj.org/article/db40a50f875644f6862eb794095e9a54
Publikováno v:
Journal of Teaching in International Business. 33:203-223
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3ed3fc58ef0e4b520a2193f5d7fcb7d
https://doi.org/10.1080/08975930.2022.2137276
https://doi.org/10.1080/08975930.2022.2137276
Autor:
Anindita Ravindran, Danthasinghe Waduge Badrajee Piyarathna, Jie Gohlke, Vasanta Putluri, Tanu Soni, Stacy Lloyd, Patricia Castro, Subramaniam Pennathur, Jeffrey A. Jones, Michael Ittmann, Nagireddy Putluri, George Michailidis, Thekkelnaycke M. Rajendiran, Arun Sreekumar
Publikováno v:
Metabolites, Vol 12, Iss 1, p 8 (2021)
African-American (AA) men are more than twice as likely to die of prostate cancer (PCa) than European American (EA) men. Previous in silico analysis revealed enrichment of altered lipid metabolic pathways in pan-cancer AA tumors. Here, we performed g
Externí odkaz:
https://doaj.org/article/d4b748a2eb2141c9a7c51357cc6c18e7