Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Arulappu A"'
Autor:
Monypenny, James, Milewicz, Hanna, Flores-Borja, Fabian, Weitsman, Gregory, Cheung, Anthony, Chowdhury, Ruhe, Burgoyne, Thomas, Arulappu, Appitha, Lawler, Katherine, Barber, Paul R., Vicencio, Jose M., Keppler, Melanie, Wulaningsih, Wahyu, Davidson, Sean M., Fraternali, Franca, Woodman, Natalie, Turmaine, Mark, Gillett, Cheryl, Franz, Dafne, Quezada, Sergio A., Futter, Clare E., Von Kriegsheim, Alex, Kolch, Walter, Vojnovic, Borivoj, Carlton, Jeremy G., Ng, Tony
Publikováno v:
In Cell Reports 17 July 2018 24(3):630-641
Autor:
James Monypenny, Hanna Milewicz, Fabian Flores-Borja, Gregory Weitsman, Anthony Cheung, Ruhe Chowdhury, Thomas Burgoyne, Appitha Arulappu, Katherine Lawler, Paul R. Barber, Jose M. Vicencio, Melanie Keppler, Wahyu Wulaningsih, Sean M. Davidson, Franca Fraternali, Natalie Woodman, Mark Turmaine, Cheryl Gillett, Dafne Franz, Sergio A. Quezada, Clare E. Futter, Alex Von Kriegsheim, Walter Kolch, Borivoj Vojnovic, Jeremy G. Carlton, Tony Ng
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 630-641 (2018)
Summary: The immunosuppressive transmembrane protein PD-L1 was shown to traffic via the multivesicular body (MVB) and to be released on exosomes. A high-content siRNA screen identified the endosomal sorting complexes required for transport (ESCRT)-as
Externí odkaz:
https://doaj.org/article/271d76a1d4d644ff8f8a80c533ecdc3e
Autor:
Muliaditan, Tamara, Halim, Leena, Whilding, Lynsey M, Draper, Benjamin, Achkova, Daniela Y, Kausar, Fahima, Glover, Maya, Bechman, Natasha, Arulappu, Appitha, Sanchez, Jenifer, Flaherty, Katie R, Obajdin, Jana, Grigoriadis, Kristiana, Antoine, Pierre, Larcombe-Young, Daniel, Hull, Caroline M, Buus, Richard, Gordon, Peter, Grigoriadis, Anita, Davies, David M, Schurich, Anna, Maher, John, Afd Pharmacology, Pharmacology
Publikováno v:
Cell reports. Medicine, 2(12), 1. Cell Press
Cell Reports Medicine
Cell Reports Medicine
Summary Second generation (2G) chimeric antigen receptors (CARs) contain a CD28 or 41BB co-stimulatory endodomain and elicit remarkable efficacy in hematological malignancies. Third generation (3G) CARs extend this linear blueprint by fusing both co-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0423b8858f00d0de8f9e8ddf630d48d
https://dspace.library.uu.nl/handle/1874/416355
https://dspace.library.uu.nl/handle/1874/416355
Autor:
Richard Beatson, Gjertrud Maurstad, Gianfranco Picco, Appitha Arulappu, Julia Coleman, Hans H Wandell, Henrik Clausen, Ulla Mandel, Joyce Taylor-Papadimitriou, Marit Sletmoen, Joy M Burchell
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125994 (2015)
Aberrant glycosylation occurs in the majority of human cancers and changes in mucin-type O-glycosylation are key events that play a role in the induction of invasion and metastases. These changes generate novel cancer-specific glyco-antigens that can
Externí odkaz:
https://doaj.org/article/ba071af7f77445f1bf0b642c2efabb36
Autor:
Tamara Muliaditan, Leena Halim, Lynsey May Whilding, Benjamin Draper, Daniela Yordanova Achkova, Fahima Kausar, Maya Glover, Natasha Bechman, Appitha Arulappu, Jenifer Sanchez, Kristina Grigoriadis, Kushal Kumar Das, Andrea Candelli, Daniel Larcombe-Young, Caroline Malai Hull, Richard Buus, Peter Gordon, Anita Grigoriadis, David Marc Davies, Anna Schurich, John Maher
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9d66dd21d6672c6ba3c7bff8bdd4eaa
https://doi.org/10.2139/ssrn.3636567
https://doi.org/10.2139/ssrn.3636567
Autor:
Michel Eisenblaetter, Gregory Weitsman, Mark Battle, Imtiaz Khan, Grethe Tang Dalsgaard, Graeme McRobbie, Susan Hoppmann, James Monypenny, Patrycja Gazinska, Wulan Wulaningsih, Appitha Arulappu, Sven Macholl, Myria Galazi, Tony Ng
Publikováno v:
Arulappu, A, Battle, M, Eisenblaetter, M, McRobbie, G, Khan, I, Monypenny, J, Weitsman, G, Galazi, M, Hoppmann, S, Gazinska, P, Wulaningsih, W, Dalsgaard, G T, Macholl, S & Ng, T 2016, ' c-Met PET Imaging Detects Early-Stage Locoregional Recurrence of Basal-Like Breast Cancer ', Journal of Nuclear Medicine, vol. 57, no. 5, pp. 765-70 . https://doi.org/10.2967/jnumed.115.164384
Locoregional recurrence of breast cancer poses significant clinical problems because of frequent inoperability once the chest wall is involved. Early detection of recurrence by molecular imaging agents against therapeutically targetable receptors, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ba65608d2f30e0dcba5b0259331c0a
https://doi.org/10.2967/jnumed.115.164384
https://doi.org/10.2967/jnumed.115.164384
Autor:
Muliaditan T; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Halim L; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Whilding LM; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Draper B; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Achkova DY; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Kausar F; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Glover M; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Bechman N; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Arulappu A; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Sanchez J; King's College London, Department of Infectious Diseases, School of Immunology and Microbial Sciences, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Flaherty KR; King's College London, Department of Infectious Diseases, School of Immunology and Microbial Sciences, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Obajdin J; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Grigoriadis K; King's College London, School of Cancer and Pharmaceutical Sciences, Cancer Bioinformatics, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Antoine P; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Larcombe-Young D; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Hull CM; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Buus R; The Breast Cancer Now Toby Robins Research Centre at The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.; Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK., Gordon P; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Grigoriadis A; King's College London, School of Cancer and Pharmaceutical Sciences, Cancer Bioinformatics, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Davies DM; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK., Schurich A; King's College London, Department of Infectious Diseases, School of Immunology and Microbial Sciences, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK., Maher J; Leucid Bio Ltd., Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.; King's College London, School of Cancer and Pharmaceutical Sciences, CAR Mechanics Lab, Guy's Cancer Centre, Great Maze Pond, London SE1 9RT, UK.; Department of Clinical Immunology and Allergy, King's College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK.; Department of Immunology, Eastbourne Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD, UK.
Publikováno v:
Cell reports. Medicine [Cell Rep Med] 2021 Dec 21; Vol. 2 (12), pp. 100457. Date of Electronic Publication: 2021 Dec 21 (Print Publication: 2021).
Autor:
Arulappu, Appitha
Basal-like subtypes of breast cancer (BLBC) account for about 15-20% of all breast cancer, affecting younger women
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700783
Autor:
Colaço, Mariana1,2,3 (AUTHOR) mariana.colaco@cnc.uc.pt, Cruz, Maria T.1,2,3 (AUTHOR) trosete@ff.uc.pt, Almeida, Luís Pereira de1,2,3 (AUTHOR) luispa@cnc.uc.pt, Borges, Olga1,2,3 (AUTHOR) olga@ci.uc.pt
Publikováno v:
Pharmaceutics. Oct2024, Vol. 16 Issue 10, p1308. 46p.