Zobrazeno 1 - 10
of 3 707
pro vyhledávání: '"Arul M"'
Autor:
Arul M. Mani, Victor Lamin, Ronan C. Peach, Eli H. Friesen, Thomas Wong, Madhu V. Singh, Ayotunde O. Dokun
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 23 (2024)
Background Peripheral arterial disease affects >200 million people worldwide and is characterized by impaired blood flow to the lower extremities. There are no effective medical treatments available. Using the mouse hind‐limb ischemia model and miR
Externí odkaz:
https://doaj.org/article/97219a33abd14408be23f06bfe1baf85
Autor:
Steven Kregel, Chao Wang, Xin Han, Lanbo Xiao, Ester Fernandez-Salas, Pushpinder Bawa, Brooke L. McCollum, Kari Wilder-Romans, Ingrid J. Apel, Xuhong Cao, Corey Speers, Shaomeng Wang, Arul M. Chinnaiyan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 57, Iss , Pp 101064- (2024)
Externí odkaz:
https://doaj.org/article/0862d758f7f1496994a5fd8a9d33c95b
Autor:
Jae Eun Choi, Yuanyuan Qiao, Ilona Kryczek, Jiali Yu, Jonathan Gurkan, Yi Bao, Mahnoor Gondal, Jean Ching-Yi Tien, Tomasz Maj, Sahr Yazdani, Abhijit Parolia, Houjun Xia, JiaJia Zhou, Shuang Wei, Sara Grove, Linda Vatan, Heng Lin, Gaopeng Li, Yang Zheng, Yuping Zhang, Xuhong Cao, Fengyun Su, Rui Wang, Tongchen He, Marcin Cieslik, Michael D. Green, Weiping Zou, Arul M. Chinnaiyan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cancer treatment continues to shift from utilizing traditional therapies to targeted ones, such as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other myeloid cells with antigen presenting and cancer cell k
Externí odkaz:
https://doaj.org/article/110a46dd843f458b99af5d4a3c335b08
Autor:
Udit Singhal, Srinivas Nallandhighal, Jeffrey J. Tosoian, Kevin Hu, Trinh M. Pham, Judith Stangl-Kremser, Chia-Jen Liu, Razeen Karim, Komal R. Plouffe, Todd M. Morgan, Marcin Cieslik, Roberta Lucianò, Shahrokh F. Shariat, Nadia Finocchio, Lucia Dambrosio, Claudio Doglioni, Arul M. Chinnaiyan, Scott A. Tomlins, Alberto Briganti, Ganesh S. Palapattu, Aaron M. Udager, Simpa S. Salami
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Localized prostate cancer is frequently composed of multiple spatially distinct tumors with significant inter- and intra-tumoral molecular heterogeneity. This genomic diversity gives rise to many competing clones that may drive the biologica
Externí odkaz:
https://doaj.org/article/62b4741b814f4ceeb89934d4333d96c5
Autor:
Jae Eun Choi, Monique E. Verhaegen, Sahr Yazdani, Rohit Malik, Paul W. Harms, Doris Mangelberger, Jean Tien, Xuhong Cao, Yuping Wang, Marcin Cieślik, Jonathan Gurkan, Mishaal Yazdani, Xiaojun Jing, Kristin Juckette, Fengyun Su, Rui Wang, Bing Zhou, Ingrid J. Apel, Shaomeng Wang, Andrzej A. Dlugosz, Arul M. Chinnaiyan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 55, Iss , Pp 101019- (2024)
Externí odkaz:
https://doaj.org/article/24f5817d471d45d98d05c47b12f71a02
Autor:
Muhammad Faisal, Aditya P. Sarnaik, Nandini Kannoju, Nima Hajinajaf, Muhammad Javaid Asad, Ryan W. Davis, Arul M. Varman
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the most abundant soluble protein in nature. Extensive studies have been conducted for improving its activity in photosynthesis through approaches like protein engineeri
Externí odkaz:
https://doaj.org/article/8d8e221318de49ac971d7f5487f5a65e
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Rapid advancements in high-throughput single-cell RNA-seq (scRNA-seq) technologies and experimental protocols have led to the generation of vast amounts of transcriptomic data that populates several online databases and repositories. Here, we systema
Externí odkaz:
https://doaj.org/article/43bc2c481c3141f5864cbec92ea63a55
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Diabetes worsens the outcomes of a number of vascular disorders including peripheral arterial disease (PAD) at least in part through induction of chronic inflammation. However, in experimental PAD, recovery requires the nuclear factor-kappa B (NF-κB
Externí odkaz:
https://doaj.org/article/a6c8b0312e0e463fb3713bd76006816a
Autor:
Reyaz ur Rasool, Caitlin M. O’Connor, Chandan Kanta Das, Mohammed Alhusayan, Brijesh Kumar Verma, Sehbanul Islam, Ingrid E. Frohner, Qu Deng, Erick Mitchell-Velasquez, Jaya Sangodkar, Aqila Ahmed, Sarah Linauer, Ingrid Mudrak, Jessica Rainey, Kaitlin P. Zawacki, Tahra K. Suhan, Catherine G. Callahan, Ryan Rebernick, Ramakrishnan Natesan, Javed Siddiqui, Guido Sauter, Dafydd Thomas, Shaomeng Wang, Derek J. Taylor, Ronald Simon, Marcin Cieslik, Arul M. Chinnaiyan, Luca Busino, Egon Ogris, Goutham Narla, Irfan A. Asangani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Loss of the tumor suppressive activity of the protein phosphatase 2A (PP2A) is associated with cancer, but the underlying molecular mechanisms are unclear. PP2A holoenzyme comprises a heterodimeric core, a scaffolding A subunit and a catalyt
Externí odkaz:
https://doaj.org/article/7ea3b219c8a941b89ece9e99f3bc0149
Autor:
Aditya P. Sarnaik, Somnath Shinde, Apurv Mhatre, Abigail Jansen, Amit Kumar Jha, Haley McKeown, Ryan Davis, Arul M. Varman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Microbial production of esters has recently garnered wide attention, but the current production metrics are low. Evidently, the ester precursors (organic acids and alcohols) can be accumulated at higher titers by microbes like Escherichia co
Externí odkaz:
https://doaj.org/article/78661650b77e4568b66b409efab85e45