Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Aru Balachandran"'
Autor:
Jifeng Bian, Sehun Kim, Sarah J Kane, Jenna Crowell, Julianna L Sun, Jeffrey Christiansen, Eri Saijo, Julie A Moreno, James DiLisio, Emily Burnett, Sandra Pritzkow, Damian Gorski, Claudio Soto, Terry J Kreeger, Aru Balachandran, Gordon Mitchell, Michael W Miller, Romolo Nonno, Turid Vikøren, Jørn Våge, Knut Madslien, Linh Tran, Tram Thu Vuong, Sylvie L Benestad, Glenn C Telling
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009748 (2021)
Prions are infectious proteins causing fatal, transmissible neurodegenerative diseases of animals and humans. Replication involves template-directed refolding of host encoded prion protein, PrPC, by its infectious conformation, PrPSc. Following its d
Externí odkaz:
https://doaj.org/article/bea6273ddd5944c1a6d5966be71ea6e1
Autor:
Laura Pirisinu, Linh Tran, Barbara Chiappini, Ilaria Vanni, Michele A. Di Bari, Gabriele Vaccari, Turid Vikøren, Knut Ivar Madslien, Jørn Våge, Terry Spraker, Gordon Mitchell, Aru Balachandran, Thierry Baron, Cristina Casalone, Christer M. Rolandsen, Knut H. Røed, Umberto Agrimi, Romolo Nonno, Sylvie L. Benestad
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 12, Pp 2210-2218 (2018)
Chronic wasting disease (CWD) persists in cervid populations of North America and in 2016 was detected for the first time in Europe in a wild reindeer in Norway. We report the detection of CWD in 3 moose (Alces alces) in Norway, identified through a
Externí odkaz:
https://doaj.org/article/cbedbb536e40440da7ec075137b07e66
Publikováno v:
Sensing and Bio-Sensing Research, Vol 11, Iss , Pp 94-98 (2016)
An acoustic prion assay has been demonstrated for sheep brain samples. Only five false positives and no false negatives were observed in a test of 45 positive and 45 negative samples. The acoustic prion sensor was constructed using a thickness shear
Externí odkaz:
https://doaj.org/article/206b5b92528c41c2a3fc68d8deb5e0b1
Autor:
Agnes Lau, Alex McDonald, Nathalie Daude, Charles E Mays, Eric D Walter, Robin Aglietti, Robert CC Mercer, Serene Wohlgemuth, Jacques van der Merwe, Jing Yang, Hristina Gapeshina, Chae Kim, Jennifer Grams, Beipei Shi, Holger Wille, Aru Balachandran, Gerold Schmitt‐Ulms, Jiri G Safar, Glenn L Millhauser, David Westaway
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 3, Pp 339-356 (2015)
Abstract The cellular prion protein (PrPC) comprises a natively unstructured N‐terminal domain, including a metal‐binding octarepeat region (OR) and a linker, followed by a C‐terminal domain that misfolds to form PrPSc in Creutzfeldt‐Jakob di
Externí odkaz:
https://doaj.org/article/5e77529f4279415d8aa0b5975d382b3d
Autor:
Marcelo A. Barria, Aru Balachandran, Masanori Morita, Tetsuyuki Kitamoto, Rona Barron, Jean Manson, Richard Knight, James W. Ironside, Mark W. Head
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 1, Pp 88-97 (2014)
The risks posed to human health by individual animal prion diseases cannot be determined a priori and are difficult to address empirically. The fundamental event in prion disease pathogenesis is thought to be the seeded conversion of normal prion pro
Externí odkaz:
https://doaj.org/article/1b6cc059690f4c69918ffde6ba9c2414
Autor:
Rachel C. Angers, Tanya S. Seward, Dana Napier, Michael Green, Edward Hoover, Terry Spraker, Katherine O’Rourke, Aru Balachandran, Glenn C. Telling
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 5, Pp 696-703 (2009)
Chronic wasting disease (CWD) is a contagious, fatal prion disease of deer and elk that continues to emerge in new locations. To explore the means by which prions are transmitted with high efficiency among cervids, we examined prion infectivity in th
Externí odkaz:
https://doaj.org/article/65a626abe3574b3dbc85f2fe6b1f6144
Autor:
Tracy A Nichols, Terry R Spraker, Tara D Rigg, Crystal Meyerett-Reid, Clare Hoover, Brady Michel, Jifeng Bian, Edward Hoover, Thomas Gidlewski, Aru Balachandran, Katherine O'Rourke, Glenn C Telling, Richard Bowen, Mark D Zabel, Kurt C VerCauteren
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62455 (2013)
Chronic wasting disease (CWD), the only known prion disease endemic in wildlife, is a persistent problem in both wild and captive North American cervid populations. This disease continues to spread and cases are found in new areas each year. Indirect
Externí odkaz:
https://doaj.org/article/519cd09084264ef8ab5eac16275fdefe
Autor:
Gordon B Mitchell, Christina J Sigurdson, Katherine I O'Rourke, James Algire, Noel P Harrington, Ines Walther, Terry R Spraker, Aru Balachandran
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39055 (2012)
Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of cervids, remains prevalent in North American elk, white-tailed deer and mule deer. A natural case of CWD in reindeer (Rangifer tarandus tarandus) has not been reported despit
Externí odkaz:
https://doaj.org/article/d724dbf07ef348f3893bf94d3d42abdc
Publikováno v:
PLoS Pathogens, Vol 2, Iss 3, p e26 (2006)
Prions cause fatal and transmissible neurodegenerative disease. These etiological infectious agents are formed in greater part from a misfolded cell-surface protein called PrP(C). Several mammalian species are affected by the diseases, and in the cas
Externí odkaz:
https://doaj.org/article/59f18930c6384907afb4139ff9044181
Autor:
Aru Balachandran, Ines Walther, Hyo-Jin Kim, Kyung-Je Park, Hyun-Joo Sohn, Andrei Soutyrine, Yoon Hee Lee, Antanas Staskevicus, Gordon Mitchell
Publikováno v:
Prion
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Chronic wasting disease (CWD) affects a broad array of cervid species and continues to be detected in an expanding geographic range. Initially introduced into the Republic of Korea through the importation of CWD-infected elk (Cervus canadensis), addi