Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Artyom Grigorov"'
Autor:
Elena Kazakova, Olga Riabova, Júlia Zemanová, Stanislav Huszár, Arseny S. Kaprelyants, Jan S. Keruchenko, Tatyana L. Azhikina, Elena G. Salina, Vadim Makarov, Artyom Grigorov, Katarína Mikušová
Publikováno v:
Metallomics. 10:992-1002
With the emerging primary resistance of Mycobacterium tuberculosis to current drugs and wide distribution of latent tuberculosis infection, the need for new compounds with a novel mode of action is growing. Copper-mediated innate immunity and its ant
Autor:
Katarína Mikušová, Fabio Gosetti, Vadim Makarov, Giovanna Riccardi, Elena A. Salina, Giorgio Mori, Alexander Lepioshkin, Jan Madacki, Emilio Marengo, Martin Forbak, Jana Korduláková, Arianna Buzzi, Beatrice Silvia Orena, Olga Riabova, Tatyana L. Azhikina, Laurent R. Chiarelli, Artyom Grigorov, Maria Rosalia Pasca, Marcello Manfredi, Giulia Degiacomi
Publikováno v:
SSRN Electronic Journal.
The thienopyrimidine TP053 is an antitubercular prodrug active against both replicating and non-replicating Mycobacterium tuberculosis cells. Its mechanism of activation involves the reduction of a NO2 group by the mycothiol-dependent reductase Mrx2,