Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Arturo Urrutia"'
Autor:
Richard Kanyo, Shawn M Lamothe, Arturo Urrutia, Samuel J Goodchild, W Ted Allison, Richard Dean, Harley T Kurata
Publikováno v:
Function.
Kv7 (KCNQ) voltage-gated potassium channels are critical regulators of neuronal excitability and are candidate targets for development of anti-seizure medications. Drug discovery efforts have identified small molecules that modulate channel function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7793776fde45d65bbbdbf7f6364b0a57
https://doi.org/10.1093/function/zqad021
https://doi.org/10.1093/function/zqad021
Autor:
Arturo Urrutia
Publikováno v:
Realidad, Iss 25 (1992)
No hay resúmenes disponibles Realidad: Revista de Ciencias Sociales y Humanidades No. 25, 1992: 49-67
Externí odkaz:
https://doaj.org/article/f32aca360140416c800b823362fe40d2
Autor:
Laura E. Chavez-Noriega, Charles J. Cohen, Mark E. Williams, Bill Burton, Jayashree Aiyar, Arturo Urrutia, Anatoly Shcherbatko
Publikováno v:
Journal of Biological Chemistry. 280:1257-1263
Expression of functional, recombinant alpha7 nicotinic acetylcholine receptors in several mammalian cell types, including HEK293 cells, has been problematic. We have isolated the recently described human ric-3 cDNA and co-expressed it in Xenopus oocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3c8ff546682fda2f8903067b38086e
https://doi.org/10.1074/jbc.m410039200
https://doi.org/10.1074/jbc.m410039200
Autor:
Daniela Pietrobon, Siro Luvisetto, Angelita Tottene, Paul Brust, Mark E. Williams, Michele Spagnolo, Edwin C. Johnson, Michael Hans, Michael M. Harpold, Arturo Urrutia, Kenneth A. Stauderman
Publikováno v:
The Journal of Neuroscience. 19:1610-1619
Mutations in α1A, the pore-forming subunit of P/Q-type calcium channels, are linked to several human diseases, including familial hemiplegic migraine (FHM). We introduced the four missense mutations linked to FHM into human α1A-2subunits and invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93349b0d6ebacafbf074b9bb32275544
https://doi.org/10.1523/jneurosci.19-05-01610.1999
https://doi.org/10.1523/jneurosci.19-05-01610.1999
Autor:
Charles R. Deal, Steven B. Ellis, Michael Hans, Arturo Urrutia, Kenneth A. Stauderman, Mark E. Williams, Paul Brust, Edwin C. Johnson, Michael M. Harpold
Publikováno v:
Biophysical Journal. 76:1384-1400
We have cloned two splice variants of the human homolog of the alpha1A subunit of voltage-gated Ca2+ channels. The sequences of human alpha1A-1 and alpha1A-2 code for proteins of 2510 and 2662 amino acids, respectively. Human alpha1A-2alpha2bdeltabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0376539f1635b5f24ab60e09fbecda
https://doi.org/10.1016/s0006-3495(99)77300-5
https://doi.org/10.1016/s0006-3495(99)77300-5
Autor:
Kenneth A. Stauderman, Arturo Urrutia, Michael M. Harpold, Paul Brust, Mark E. Williams, Patricia Prodanovich, Michael Hans, Mark S. Washburn
Publikováno v:
Journal of Neurochemistry. 72:791-799
We have isolated and characterized overlapping cDNAs encoding a novel, voltage-gated Ca2+ channel alpha1 subunit, alpha1H, from a human medullary thyroid carcinoma cell line. The alpha1H subunit is structurally similar to previously described alpha1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ae0425322000fedbde2436f2353fbf
https://doi.org/10.1046/j.1471-4159.1999.0720791.x
https://doi.org/10.1046/j.1471-4159.1999.0720791.x
Autor:
Kathryn J. Elliott, Gonul Velicelebi, Steven B. Ellis, Michael M. Harpold, Arturo Urrutia, Edwin C. Johnson, Kelly J. Berckhan, Laura E. Chavez-Noriega
Publikováno v:
Journal of Molecular Neuroscience. 7:217-228
cDNA clones encoding human neuronal nicotinic acetylcholine receptor α2, α3, α4, α5, α6, α7, β2, β3, and β4 subunits were isolated from brainstem, hippocampus, prefrontal cortex, substantia nigra, thalamus, and IMR32 libraries. Human α2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff0c52832f5977a69509bbf43dc3689
https://doi.org/10.1007/bf02736842
https://doi.org/10.1007/bf02736842
Autor:
Arturo Urrutia, Donna L. Gruol
Publikováno v:
Brain Research. 569:26-37
Acute exposure to ethanol at 22 and 44 mM concentrations altered several features of the current-evoked voltage responses of cerebellar Purkinje neurons and hippocampal neurons studied in culture model systems. Whole cell current clamp techniques wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9992ea789077c69a6c7c63792d7167af
https://doi.org/10.1016/0006-8993(92)90365-g
https://doi.org/10.1016/0006-8993(92)90365-g
Autor:
Tadimeti S. Rao, G. Kenneth Lloyd, Jean-Michel Vernier, Nicholas D. P. Cosford, Laura E. Chavez-Noriega, Frédérique Menzaghi, Arturo Urrutia, Carla Suto, Heather Holsenback, Aida I. Sacaan, Ian A. McDonald, Mark S. Washburn, Jeffrey P. Whitten, R. T. Reid
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(16)
A series of conformationally restricted analogues of nicotine has been synthesized and evaluated as agonists of neuronal acetylcholine receptors. Compound 2 (SIB-1663), which selectively activated human recombinant alpha 2 beta 4 and alpha 4 beta 4 n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2178f568ace913b70d0f413355174731
https://pubmed.ncbi.nlm.nih.gov/9873508
https://pubmed.ncbi.nlm.nih.gov/9873508