Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Arturo SAN FELICIANO"'
Autor:
Pablo A. García, Ángela-Patricia Hernández, Mª Antonia Gómez-Zurita, José M. Miguel del Corral, Marina Gordaliza, Andrés Francesch, Arturo San Feliciano, Mª Ángeles Castro
Publikováno v:
Molecules, Vol 29, Iss 7, p 1442 (2024)
Podophyllotoxin, a cyclolignan natural product, has been the object of extensive chemomodulation to obtain better chemotherapeutic agents. Among the obtained podophyllotoxin derivatives, podophyllic aldehyde showed very interesting potency and select
Externí odkaz:
https://doaj.org/article/345d99c08e444b21b8677d7c59dcd9f1
Autor:
Elora Valderas-García, Nerea Escala, María Álvarez-Bardón, Verónica Castilla-Gómez de Agüero, Maria Cambra-Pellejà, Laura González del Palacio, Raquel Vallejo García, Jennifer de la Vega, Arturo San Feliciano, Esther del Olmo, María Martínez-Valladares, Rafael Balaña-Fouce
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract The control of gastrointestinal nematodes in livestock is becoming increasingly difficult due to the limited number of available drugs and the rapid development of anthelmintic resistance. Therefore, it is imperative to develop new anthelmin
Externí odkaz:
https://doaj.org/article/32ddcdb54a7d4167a2b40a76dd00975c
Autor:
Ángela-Patricia Hernández, Paula Díez, Pablo A. García, Martín Pérez-Andrés, Anzhela Veselinova, Pablo G. Jambrina, Arturo San Feliciano, David Díez, Manuel Fuentes, Mᵃ Ángeles Castro
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 886 (2023)
New lignohydroquinone conjugates (L-HQs) were designed and synthesized using the hybridization strategy, and evaluated as cytotoxics against several cancer cell lines. The L-HQs were obtained from the natural product podophyllotoxin and some semisynt
Externí odkaz:
https://doaj.org/article/c9850c81e4d943de8dcea844f62c72a5
Autor:
Helena Quintero-Pertuz, Ruben Veas-Albornoz, Ileana Carrillo, Fabiola González-Herrera, Michel Lapier, Eduino Carbonó-Delahoz, Esther del Olmo, Arturo San Feliciano, Ulrike Kemmerling, Claudio Olea-Azar, Carla Delporte, Juan D. Maya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112761- (2022)
The deficit of effective treatments for Chagas disease has led to searching for new substances with therapeutic potential. Natural products possess a wide variety of chemical structural motifs and are thus a valuable source of diverse lead compounds
Externí odkaz:
https://doaj.org/article/5c56be63178e474dbd6dd0fd11ac431e
Autor:
Yolanda Pérez-Pertejo, José M. Escudero-Martínez, Rosa M. Reguera, Rafael Balaña-Fouce, Pablo A. García, Pablo G. Jambrina, Arturo San Feliciano, María-Ángeles Castro
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss , Pp 70-79 (2019)
Leishmania is the aethiological agent responsible for the visceral leishmaniasis, a serious parasite-borne disease widely spread all over the World. The emergence of resistant strains makes classical treatments less effective; therefore, new and bett
Externí odkaz:
https://doaj.org/article/89a1aeed6c334008b744cdbeed6d6f6b
Autor:
Katia Peñuelas-Urquides, Mario Bermúdez de León, Beatriz Silva-Ramírez, Fabiola Castorena-Torres, Gloria María Molina-Salinas, Jorge Castro-Garza, Pola Becerril-Montes, Esther del Olmo, Arturo San Feliciano, Laura Adiene González-Escalante, Licet Villarreal-Treviño, Salvador Said-Fernández
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The emergence of multidrug-resistant (MDR) Mycobacterium tuberculosis strains threaten the control of tuberculosis. New antitubercular dihydrosphingosine analogs, named UCIs, have been evaluated in preclinical studies but their cellular and molecular
Externí odkaz:
https://doaj.org/article/8c71995d4a3f45baa47bf25076aaa18f
Publikováno v:
Vitae, Vol 27, Iss 2 (2020)
Background: Passiflora quadrangularis L. has antihypertensive and anxiolytic properties observed in experimental models. Objectives: The aim of this work was to establish the vascular effects exerted by two known monodesmosidic triterpene saponins, 3
Externí odkaz:
https://doaj.org/article/c9c04c1165df4bb29af447a2c930329f
Autor:
José Miguel Escudero-Martínez, Yolanda Pérez-Pertejo, Rosa M. Reguera, María Ángeles Castro, María Victoria Rojo, Carolina Santiago, Andrés Abad, Pablo Anselmo García, José Luis López-Pérez, Arturo San Feliciano, Rafael Balaña-Fouce
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 7, Iss 3, Pp 272-285 (2017)
Leishmania microtubules play an important role not only in cell division, but also in keeping the shape of the parasite and motility of its free-living stages. Microtubules result from the self-assembly of alpha and beta tubulins, two phylogeneticall
Externí odkaz:
https://doaj.org/article/bef44e16a2664ab8b749a9e00c6bf61c
Autor:
Ángela P. Hernández, Pablo Chamorro, Mª Lucena Rodríguez, José M. Miguel del Corral, Pablo A. García, Andrés Francesch, Arturo San Feliciano, Mª Ángeles Castro
Publikováno v:
Molecules, Vol 26, Iss 2, p 474 (2021)
Terpenylquinones are mixed biogenesis primary or secondary metabolites widespread in Nature with many biological activities, including the antineoplastic cytotoxicity, that have inspired this work. Here, we present a cytotoxic structure-activity rela
Externí odkaz:
https://doaj.org/article/ef7f16af347c4101b977ba1642e68503
Autor:
Aurora Molinari, Alfonso Oliva, Marlene Arismendi-Macuer, Leda Guzmán, Mauricio Fuentealba, Marcela Knox, Raúl Vinet, Arturo San Feliciano
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 21924-21938 (2015)
1H-Benzo[f]indazole-4,9-dione derivatives conjugated with C-protected amino acids (glycine, l-alanine, l-phenylalanine and l-glutamic acid) 6a–l were prepared by chemically modifying the prenyl substituent of 3-methyl-7-(4-methylpent-3-enyl)-1H-ben
Externí odkaz:
https://doaj.org/article/95f5f1d9ea0c41c4a36cd7c2dbc2c2fa